scholarly article | Q13442814 |
P50 | author | Wenjun Zhang | Q56428183 |
P2093 | author name string | Wenlong Cai | |
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Substrate structure-activity relationships guide rational engineering of modular polyketide synthase ketoreductases | Q41968771 | ||
Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry | Q42126323 | ||
Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis | Q42139318 | ||
Elucidation of the Stereospecificity of C-Methyltransferases from trans-AT Polyketide Synthases | Q44182561 | ||
Broad substrate specificity of the loading didomain of the lipomycin polyketide synthase | Q44734237 | ||
Mutant malonyl-CoA synthetases with altered specificity for polyketide synthase extender unit generation | Q44866313 | ||
Comprehensive in Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production. | Q45951684 | ||
Alteration of Polyketide Stereochemistry from anti to syn by a Ketoreductase Domain Exchange in a Type I Modular Polyketide Synthase Subunit. | Q45971460 | ||
In vitro analysis of carboxyacyl substrate tolerance in the loading and first extension modules of borrelidin polyketide synthase. | Q46120822 | ||
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Divergent mechanistic routes for the formation of gem-dimethyl groups in the biosynthesis of complex polyketides. | Q46175180 | ||
Engineering a Polyketide Synthase for In Vitro Production of Adipic Acid. | Q46557528 | ||
Mechanism and Stereochemistry of Polyketide Chain Elongation and Methyl Group Epimerization in Polyether Biosynthesis. | Q46858188 | ||
Broadening substrate specificity of a chain-extending ketosynthase through a single active-site mutation | Q48509192 | ||
Evaluating Ketoreductase Exchanges as a Means of Rationally Altering Polyketide Stereochemistry | Q48514837 | ||
Engineering an iterative polyketide pathway in Escherichia coli results in single-form alkene and alkane overproduction. | Q54276172 | ||
Recent Advances in Understanding and Engineering Polyketide Synthesis | Q26766621 | ||
Structural Basis for Binding Specificity between Subclasses of Modular Polyketide Synthase Docking Domains | Q27653436 | ||
Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase | Q27728317 | ||
Microbial engineering for the production of advanced biofuels | Q28273134 | ||
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Architectures of whole-module and bimodular proteins from the 6-deoxyerythronolide B synthase | Q34824345 | ||
Fuelling the future: microbial engineering for the production of sustainable biofuels | Q35973390 | ||
Protein-Protein Interactions, Not Substrate Recognition, Dominate the Turnover of Chimeric Assembly Line Polyketide Synthases | Q36035795 | ||
Bacterial Genome Mining of Enzymatic Tools for Alkyne Biosynthesis. | Q36386312 | ||
Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis. | Q36607621 | ||
Epimerase and Reductase Activities of Polyketide Synthase Ketoreductase Domains Utilize the Same Conserved Tyrosine and Serine Residues | Q36642490 | ||
α-Methylation follows condensation in the gephyronic acid modular polyketide synthase | Q37102010 | ||
Methyltransferases excised from trans-AT polyketide synthases operate on N-acetylcysteamine-bound substrates | Q37131565 | ||
In vitro reconstitution and analysis of the 6-deoxyerythronolide B synthase | Q37382344 | ||
Engineering the acyltransferase substrate specificity of assembly line polyketide synthases | Q37677554 | ||
PKS and NRPS release mechanisms | Q37683524 | ||
Beyond ethylmalonyl-CoA: the functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity | Q37962381 | ||
Assembly line polyketide synthases: mechanistic insights and unsolved problems | Q38208037 | ||
Stereocontrol within polyketide assembly lines | Q38264057 | ||
Recent advances in the biosynthesis of unusual polyketide synthase substrates | Q38264066 | ||
Decoding and reprogramming complex polyketide assembly lines: prospects for synthetic biology | Q38372217 | ||
Creating pathways towards aromatic building blocks and fine chemicals | Q38564831 | ||
Engineering of oleaginous organisms for lipid production. | Q38576412 | ||
Engineering Biosynthesis of Non-ribosomal Peptides and Polyketides by Directed Evolution | Q38604504 | ||
Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology | Q38629855 | ||
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Engineered fatty acid catabolism for fuel and chemical production. | Q38956371 | ||
Bio-based production of fuels and industrial chemicals by repurposing antibiotic-producing type I modular polyketide synthases: opportunities and challenges | Q39009631 | ||
Type III Polyketide Synthases: Functional Classification and Phylogenomics. | Q39013122 | ||
New insights into bacterial type II polyketide biosynthesis. | Q39181168 | ||
P921 | main subject | biofuel | Q128991 |
P304 | page(s) | 32-38 | |
P577 | publication date | 2017-09-22 | |
P1433 | published in | Current Opinion in Biotechnology | Q15763085 |
P1476 | title | Engineering modular polyketide synthases for production of biofuels and industrial chemicals | |
P478 | volume | 50 |
Q98282975 | A bimodular PKS platform that expands the biological design space |
Q64897732 | Acyltransferases as Tools for Polyketide Synthase Engineering. |
Q90417487 | Development of a cyanobacterial heterologous polyketide production platform |
Q64887003 | Marine Spirotetronates: Biosynthetic Edifices That Inspire Drug Discovery. |
Q64263635 | Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold |
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