Neuronal acetylcholine receptors with alpha7 subunits are concentrated on somatic spines for synaptic signaling in embryonic chick ciliary ganglia

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Neuronal acetylcholine receptors with alpha7 subunits are concentrated on somatic spines for synaptic signaling in embryonic chick ciliary ganglia is …
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scholarly articleQ13442814

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P698PubMed publication ID9880590

P2093author name stringYamada N
Ellisman MH
Berg DK
Martone ME
Shoop RD
P2860cites workDevelopmental changes in the structure of the synapse on the myelinated cell bodies of the chicken ciliary ganglionQ30494637
Quantitation of junctional and extrajunctional acetylcholine receptors by electron microscope autoradiography after 125I-alpha-bungarotoxin binding at mouse neuromuscular junctionsQ31126900
The function of dendritic spines: devices subserving biochemical rather than electrical compartmentalization.Q34359750
Shared antigenic determinant between the Electrophorus acetylcholine receptor and a synaptic component on chicken ciliary ganglion neuronsQ36261816
Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptorQ36443394
The ultrastructural localization of alpha-bungarotoxin binding sites in relation to synapses on chick ciliary ganglion neurons.Q36631925
Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calciumQ36695036
Perisynaptic surface distribution of multiple classes of nicotinic acetylcholine receptors on neurons in the chicken ciliary ganglion.Q36797210
Morphology of synapses in the autonomic nervous systemQ39564701
Functional development of the parasympathetic neurons of the avian ciliary ganglion: a classic model system for the study of neuronal differentiation and developmentQ40566529
Dendritic spines: cellular specializations imparting both stability and flexibility to synaptic functionQ40766021
The ultrastructural distribution of putative nicotinic receptors on cultured neurons from the rat superior cervical ganglionQ41437793
Characterization of a component in chick ciliary ganglia that cross-reacts with monoclonal antibodies to muscle and electric organ acetylcholine receptorQ42116157
Novel subpopulation of neuronal acetylcholine receptors among those binding alpha-bungarotoxin.Q43831783
Neurons in culture maintain acetylcholine receptor levels with far fewer transcripts than in vivoQ43913114
Direct recording of nicotinic responses in presynaptic nerve terminalsQ44776051
Neuronal acetylcholine receptors that bind alpha-bungarotoxin with high affinity function as ligand-gated ion channels.Q45946124
Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes.Q45973399
Nicotinic receptor subtypes in the developing chick brain: appearance of a species containing the alpha4, beta2, and alpha5 gene productsQ46075688
Synaptic currents generated by neuronal acetylcholine receptors sensitive to alpha-bungarotoxinQ46097771
Brain alpha-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamilyQ46132373
Electron tomography of large, multicomponent biological structuresQ46184320
Programs for visualization in three-dimensional microscopyQ46307109
Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositionsQ46358868
Serial section electron tomography: a method for three-dimensional reconstruction of large structuresQ46408343
Coexpression of multiple acetylcholine receptor genes in neurons: quantification of transcripts during developmentQ46470129
Rapid synaptic transmission in the avian ciliary ganglion is mediated by two distinct classes of nicotinic receptors.Q46580714
Homomeric and native alpha 7 acetylcholine receptors exhibit remarkably similar but non-identical pharmacological properties, suggesting that the native receptor is a heteromeric protein complexQ48246773
Glutamate and GABA release are enhanced by different subtypes of presynaptic nicotinic receptors in the lateral geniculate nucleus.Q48489795
Presynaptic nicotinic receptors facilitate monoaminergic transmission.Q48519580
The alpha-bungarotoxin-binding nicotinic acetylcholine receptor from rat brain contains only the alpha7 subunitQ48628440
A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTXQ48856964
Hippocampal synaptic transmission enhanced by low concentrations of nicotine.Q48887721
Neuronal nicotinic alpha 7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitineQ49019546
Synapse formation during embryogenesis on ganglion cells lacking a periphery.Q52315580
The structure of the autonomic interneuronal synapseQ56565656
Time course of appearance of alpha-bungarotoxin binding sites during development of chick ciliary ganglion and irisQ67444029
Adrenergic nerve elements in the hypogastric ganglion of the guinea pigQ68623362
The onset and development of transmission in the chick ciliary ganglionQ68642833
Ultrastructural distribution of 125I-toxin F binding sites on chick ciliary neurons: synaptic localization of a toxin that blocks ganglionic nicotinic receptorsQ69146278
Localization of alpha-bungarotoxin binding sites in the ciliary ganglion of the embryonic chick: an autoradiographic study at the light and electron microscopic levelQ70094159
Differential regulation of acetylcholine sensitivity and alpha-bungarotoxin-binding sites on ciliary ganglion neurons in cell cultureQ71073632
Transmitter timecourse in the synaptic cleft: its role in central synaptic functionQ71301302
Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptorsQ71768164
Special somatic spine synapses in the ciliary ganglion of the chickQ71963441
Studies on the pararenal ganglion of the toad Bufo arenarum Hensel. I. Its normal fine structure and histochemical characteristicsQ72294475
Axosomatic synapses of the rat ciliary ganglionQ73301648
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)692-704
P577publication date1999-01-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleNeuronal acetylcholine receptors with alpha7 subunits are concentrated on somatic spines for synaptic signaling in embryonic chick ciliary ganglia
P478volume19

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cites work (P2860)
Q41704311Actin filaments and the opposing actions of CaM kinase II and calcineurin in regulating alpha7-containing nicotinic receptors on chick ciliary ganglion neurons
Q34560210Clustering of nicotinic acetylcholine receptors: from the neuromuscular junction to interneuronal synapses
Q41736771Cytoskeletal links of neuronal acetylcholine receptors containing alpha 7 subunits.
Q33598688Differential regulation of alpha7 nicotinic receptor gene (CHRNA7) expression in schizophrenic smokers
Q92856626Distribution of α7 Nicotinic Acetylcholine Receptor Subunit mRNA in the Developing Mouse
Q36761685EphB receptors co-distribute with a nicotinic receptor subtype and regulate nicotinic downstream signaling in neurons
Q24597022Evidence for ectopic neurotransmission at a neuronal synapse
Q44132604Extrasynaptic alpha 7-nicotinic acetylcholine receptor expression in developing neurons is regulated by inputs, targets, and activity.
Q52712570Fast synaptic transmission in the goldfish CNS mediated by multiple nicotinic receptors.
Q48887869Functional nicotinic acetylcholine receptors that mediate ganglionic transmission in cardiac parasympathetic neurons.
Q42609381Lateral mobility of nicotinic acetylcholine receptors on neurons is determined by receptor composition, local domain, and cell type
Q31841028Membrane lipid rafts are necessary for the maintenance of the (alpha)7 nicotinic acetylcholine receptor in somatic spines of ciliary neurons.
Q37009891Multiple cell adhesion molecules shaping a complex nicotinic synapse on neurons
Q44999257Neuronal nicotinic synapse assembly requires the adenomatous polyposis coli tumor suppressor protein.
Q41650642Nicotinic acetylcholine receptors containing alpha7 subunits are required for reliable synaptic transmission in situ
Q47739924Nicotinic acetylcholine receptors in neuropathic and inflammatory pain.
Q41481122Nicotinic receptors concentrated in the subsynaptic membrane do not contribute significantly to synaptic currents at an embryonic synapse in the chicken ciliary ganglion
Q46079943Nicotinic signal transduction machinery
Q35848221PICK1 interacts with alpha7 neuronal nicotinic acetylcholine receptors and controls their clustering.
Q30493937Prostate stem cell antigen is an endogenous lynx1-like prototoxin that antagonizes alpha7-containing nicotinic receptors and prevents programmed cell death of parasympathetic neurons
Q45249983Rapid activity-driven SNARE-dependent trafficking of nicotinic receptors on somatic spines.
Q33919096Receptor targeting and heterogeneity at interneuronal nicotinic cholinergic synapses in vivo
Q46058018Reversible inhibition of GABAA receptors by alpha7-containing nicotinic receptors on the vertebrate postsynaptic neurons
Q30491841Smoking, Genetics and Schizophrenia: Evidence for Self Medication
Q31826715Synaptically driven calcium transients via nicotinic receptors on somatic spines.
Q33747790Synchronous and asynchronous transmitter release at nicotinic synapses are differentially regulated by postsynaptic PSD-95 proteins
Q24794830The pro-apoptotic Bcl-2 family member tBid localizes to mitochondrial contact sites
Q40490738The role of palmitoylation in functional expression of nicotinic alpha7 receptors.
Q38560778The therapeutic potential of α7 nicotinic acetylcholine receptor (α7 nAChR) agonists for the treatment of the cognitive deficits associated with schizophrenia
Q30492632Transient expression of acetylcholinesterase in the posterior ventral cochlear nucleus of rat brain.
Q73900899Two distinct classes of functional 7-containing nicotinic receptor on rat superior cervical ganglion neurons
Q46072770Ultrastructure of a somatic spine mat for nicotinic signaling in neurons.
Q35929504α7-Containing and non-α7-containing nicotinic receptors respond differently to spillover of acetylcholine

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