Activation of cord blood myeloid dendritic cells by Trypanosoma cruzi and parasite-specific antibodies, proliferation of CD8+ T cells, and production of IFN-γ.

scientific article

Activation of cord blood myeloid dendritic cells by Trypanosoma cruzi and parasite-specific antibodies, proliferation of CD8+ T cells, and production of IFN-γ. is …
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scholarly articleQ13442814

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P356DOI10.1007/S00430-011-0217-Y
P698PubMed publication ID22037700
P5875ResearchGate publication ID51752410

P50authorYves CarlierQ90922594
Carine TruyensQ97085191
P2093author name stringPatricia Rodriguez
P2860cites workCD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cellsQ24528149
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Maternal infection with Trypanosoma cruzi and congenital Chagas disease induce a trend to a type 1 polarization of infant immune responses to vaccinesQ33521186
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Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily.Q34307897
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Neonatal dendritic cells are intrinsically biased against Th-1 immune responsesQ78024334
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Cord blood dendritic cells prevent the differentiation of naïve T-helper cells towards Th1 irrespective of their subtypeQ79774513
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A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI.Q37660962
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Trypanosoma cruzi infects human dendritic cells and prevents their maturation: inhibition of cytokines, HLA-DR, and costimulatory molecules.Q39511343
Glycoinositolphospholipids from Trypanosoma cruzi interfere with macrophages and dendritic cell responses.Q39655557
Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi.Q39964182
CD83 expression on dendritic cells and T cells: correlation with effective immune responsesQ40170841
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Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificityQ41843310
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Neu1 desialylation of sialyl alpha-2,3-linked beta-galactosyl residues of TOLL-like receptor 4 is essential for receptor activation and cellular signalingQ43268535
Decreased yield, phenotypic expression and function of immature monocyte-derived dendritic cells in cord bloodQ43591864
The Trypanosoma cruzi Tc52-released protein induces human dendritic cell maturation, signals via Toll-like receptor 2, and confers protection against lethal infectionQ44021528
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Impaired responses to toll-like receptor 4 and toll-like receptor 3 ligands in human cord bloodQ44806367
Type I IFN substitutes for T cell help during viral infectionsQ45309998
Absolute values of dendritic cell subsets in bone marrow, cord blood, and peripheral blood enumerated by a novel methodQ47918331
Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi.Q51822633
Bystander activation of CD4+ T cells.Q51886353
Deficient IL-12(p35) gene expression by dendritic cells derived from neonatal monocytes.Q52141588
Preferential production of the IL-12(p40)/IL-23(p19) heterodimer by dendritic cells from human newborns.Q54627231
Mycobacterium bovis bacillus Calmette-Guerin treated human cord blood monocyte-derived dendritic cells polarize naïve T cells into a tolerogenic phenotype in newbornsQ56899626
Activation of human peripheral blood dendritic cells induces the CD86 co-stimulatory moleculeQ56909409
Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cellsQ57158204
Trypanosoma cruzi infection in mice induces a polyisotypic hypergammaglobulinaemia and parasite-specific response involving high IgG2a concentrations and highly avid IgG1 antibodiesQ58844032
Monocyte-derived dendritic cells from chagasic patients vs healthy donors secrete differential levels of IL-10 and IL-12 when stimulated with a protein fragment of Trypanosoma cruzi heat-shock protein-70Q58844735
Congenital infection with Trypanosoma cruzi: from mechanisms of transmission to strategies for diagnosis and controlQ58845891
Identification of both myeloid CD11c+ and lymphoid CD11c- dendritic cell subsets in cord bloodQ61656639
Cross-Linking of CD32 Induces Maturation of Human Monocyte-Derived Dendritic Cells Via NF- B Signaling PathwayQ61771039
Stochastic Model of T Cell Proliferation: A Calculus Revealing IL-2 Regulation of Precursor Frequencies, Cell Cycle Time, and SurvivalQ61853706
Human blood contains two subsets of dendritic cells, one immunologically mature and the other immatureQ71656310
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Studies of human cord blood dendritic cells: evidence for functional immaturityQ72891642
Human fetuses are able to mount an adultlike CD8 T-cell responseQ74676091
P433issue2
P921main subjectTrypanosoma cruziQ150162
dendritic cellQ506253
antibodyQ79460
P1104number of pages13
P304page(s)157-169
P577publication date2011-10-29
P1433published inMedical Microbiology and ImmunologyQ15760239
P1476titleActivation of cord blood myeloid dendritic cells by Trypanosoma cruzi and parasite-specific antibodies, proliferation of CD8+ T cells, and production of IFN-γ.
P478volume201

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cites work (P2860)
Q35810759Congenital Chagas disease: an update
Q93047539Congenital Transmission of Trypanosoma cruzi: A Review About the Interactions Between the Parasite, the Placenta, the Maternal and the Fetal/Neonatal Immune Responses
Q26740647Dendritic Cells: A Double-Edged Sword in Immune Responses during Chagas Disease
Q36054091Molecular Characterization and Immune Protection of a New Conserved Hypothetical Protein of Eimeria tenella
Q34789819Monocytes play an IL-12-dependent crucial role in driving cord blood NK cells to produce IFN-g in response to Trypanosoma cruzi
Q34181705Mother-to-Child Transmission of Trypanosoma cruzi
Q44174009Response to Trypanosoma cruzi by Human Blood Cells Enriched with Dentritic Cells Is Controlled by Cyclooxygenase-2 Pathway
Q58843474Trypanosoma cruzi activates cord blood myeloid dendritic cells independently of cell infection