Adiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed rats

scientific article

Adiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPREGU.90774.2008
P698PubMed publication ID19073900
P5875ResearchGate publication ID23654798

P50authorAdrian ChabowskiQ30902432
David C. WrightQ89459465
Arend BonenQ123180159
P2093author name stringDavid J Dyck
Laelie A Snook
Janet Pritchard
Ian Ritchie
Kerry L Mullen
P2860cites workAdiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinaseQ24309462
AKT/PKB signaling: navigating downstreamQ24657857
Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndromeQ28205305
Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytesQ28275582
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30Q28511676
Insulin-mediated phosphorylation of the proline-rich Akt substrate PRAS40 is impaired in insulin target tissues of high-fat diet-fed ratsQ28568487
Fatty acid transport and FAT/CD36 are increased in red but not in white skeletal muscle of ZDF ratsQ28573303
Expression of the adiponectin receptors AdipoR1 and AdipoR2 in lean rats and in obese Zucker ratsQ28578146
Metformin and exercise reduce muscle FAT/CD36 and lipid accumulation and blunt the progression of high-fat diet-induced hyperglycemiaQ28581219
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesityQ29616103
DAG accumulation from saturated fatty acids desensitizes insulin stimulation of glucose uptake in muscle cellsQ31833471
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activationQ34416242
Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolitesQ34476883
Changes in adiponectin, its receptors and AMPK activity in tissues of diet-induced diabetic miceQ34742098
Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitusQ35824553
High-fat diets cause insulin resistance despite an increase in muscle mitochondriaQ36693972
Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivityQ38341759
Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells.Q40477131
Globular adiponectin resistance develops independently of impaired insulin-stimulated glucose transport in soleus muscle from high-fat-fed ratsQ42170113
Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitateQ42476162
Increased efficiency of fatty acid uptake contributes to lipid accumulation in skeletal muscle of high fat-fed insulin-resistant ratsQ42520654
A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acidsQ44276635
Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabeticsQ46381308
AMP kinase activation with AICAR simultaneously increases fatty acid and glucose oxidation in resting rat soleus muscleQ46387224
Decreasing intramuscular phosphagen content simultaneously increases plasma membrane FAT/CD36 and GLUT4 transporter abundanceQ46466578
The stimulatory effect of globular adiponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjectsQ46774709
Acute physical exercise reverses S-nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet-induced obese Wistar rats.Q46921006
Endurance training in obese humans improves glucose tolerance and mitochondrial fatty acid oxidation and alters muscle lipid contentQ46933158
Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in MuscleQ54986901
Regulation of adiponectin and its receptors in response to development of diet-induced obesity in miceQ58390488
P433issue2
P921main subjectinsulin resistanceQ1053470
lipidQ11367
P304page(s)R243-51
P577publication date2008-12-10
P1433published inAmerican Journal of Physiology - Regulatory, Integrative and Comparative PhysiologyQ2201819
P1476titleAdiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed rats
P478volume296

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cites work (P2860)
Q42852208A decreased n-6/n-3 ratio in the fat-1 mouse is associated with improved glucose tolerance.
Q37692552Adipokines and insulin action: A sensitive issue
Q37486025Adipokines as regulators of muscle metabolism and insulin sensitivity
Q37801870Adiponectin action from head to toe.
Q50475289Adiponectin is sufficient, but not required, for exercise-induced increases in the expression of skeletal muscle mitochondrial enzymes.
Q33577630Adiponectin resistance and vascular dysfunction in the hyperlipidemic state
Q26745026Adiponectin resistance in skeletal muscle: pathophysiological implications in chronic heart failure
Q50957771Adiponectin-Resistance in Obesity.
Q38054603Adiponectin: key role and potential target to reverse energy wasting in chronic heart failure
Q36496035Adipose tissue biology and cardiomyopathy: translational implications
Q34539256Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet
Q40693150Alterations in skeletal muscle fatty acid handling predisposes middle-aged mice to diet-induced insulin resistance
Q64231858BuShenKangShuai Tablet Alleviates Hepatic Steatosis via Improving Liver Adiponectin Resistance in ApoE Mice
Q38687619Cardiovascular Adiponectin Resistance: The Critical Role of Adiponectin Receptor Modification.
Q50210199Development of metabolic syndrome in high-sucrose diet fed rats is not associated with decrease in adiponectin levels
Q34947370Differential regulation of dihydroceramide desaturase by palmitate versus monounsaturated fatty acids: implications for insulin resistance
Q34101886Effects of Endurance Exercise and High-Fat Diet on Insulin Resistance and Ceramide Contents of Skeletal Muscle in Sprague-Dawley Rats
Q37424332Effects of acute exercise and chronic exercise on the liver leptin-AMPK-ACC signaling pathway in rats with type 2 diabetes
Q34448732Enhanced Energy Expenditure, Glucose Utilization, and Insulin Sensitivity in VAMP8 Null Mice
Q92537528Examining the Potential of Developing and Implementing Use of Adiponectin-Targeted Therapeutics for Metabolic and Cardiovascular Diseases
Q42480029Extremely rapid increase in fatty acid transport and intramyocellular lipid accumulation but markedly delayed insulin resistance after high fat feeding in rats
Q33851439Feeding butter with elevated content of trans-10, cis-12 conjugated linoleic acid to lean rats does not impair glucose tolerance or muscle insulin response
Q54540132Fish oil prevents high-saturated fat diet-induced impairments in adiponectin and insulin response in rodent soleus muscle.
Q37855653Functional adiponectin resistance and exercise intolerance in heart failure.
Q35528402G-protein-coupled receptor kinase 2-mediated desensitization of adiponectin receptor 1 in failing heart
Q30279123Globular adiponectin ameliorates metabolic insulin resistance via AMPK-mediated restoration of microvascular insulin responses
Q35947412Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging
Q35181153Hydrogen sulfide attenuates high fat diet-induced cardiac dysfunction via the suppression of endoplasmic reticulum stress.
Q37390991Interactions of exercise training and high-fat diet on adiponectin forms and muscle receptors in mice
Q54688685Is adiponectin a bystander or a mediator in heart failure? The tangled thread of a good-natured adipokine in aging and cardiovascular disease.
Q34167803Lack of association between body mass index and plasma adiponectin levels in healthy adults
Q35927659Long-term high-fat-diet feeding induces skeletal muscle mitochondrial biogenesis in rats in a sex-dependent and muscle-type specific manner.
Q42938078Maternal deprivation has sexually dimorphic long-term effects on hypothalamic cell-turnover, body weight and circulating hormone levels.
Q54378773Modulation of visceral fat adipokine secretion by dietary fatty acids and ensuing changes in skeletal muscle inflammation.
Q57587385Muscle ceramide content is similar after 3 weeks’ consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes
Q37618124Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects
Q28081152Obesity and cancer progression: is there a role of fatty acid metabolism?
Q52348579Plasma adiponectin levels are correlated with body composition, metabolic profiles, and mitochondrial markers in individuals with chronic spinal cord injury.
Q34533290Rapid loss of adiponectin-stimulated fatty acid oxidation in skeletal muscle of rats fed a high fat diet is not due to altered muscle redox state
Q35173617Reduced cardioprotective action of adiponectin in high-fat diet-induced type II diabetic mice and its underlying mechanisms.
Q43504116Reduced high-molecular-weight adiponectin is an independent risk factor for cardiovascular lesions in hypercholesterolaemic patients
Q33998524Reduced vascular responsiveness to adiponectin in hyperlipidemic rats--mechanisms and significance
Q35683960Regulation of glucose and lipid homeostasis by adiponectin: effects on hepatocytes, pancreatic β cells and adipocytes
Q52605177Restoration of skeletal muscle leptin response does not precede the exercise-induced recovery of insulin-stimulated glucose uptake in high-fat-fed rats.
Q48308518Sex differences in the regulation of porcine coronary artery tone by perivascular adipose tissue: a role of adiponectin?
Q38261195Skeletal muscle glucose metabolism and inflammation in the development of the metabolic syndrome.
Q43016757Skeletal muscle inflammation is not responsible for the rapid impairment in adiponectin response with high-fat feeding in rats
Q36953873Skeletal muscle insulin resistance in hamsters with diabetes developed from obesity is involved in abnormal skeletal muscle LXR, PPAR and SREBP expression
Q64244635Sustained Intermittent Hypoxemia Induces Adiponectin Oligomers Redistribution and a Tissue-Specific Modulation of Adiponectin Receptor in Mice
Q35173604Systemic adiponectin malfunction as a risk factor for cardiovascular disease
Q37798716Systemic effects of white adipose tissue dysregulation and obesity-related inflammation
Q34947724The MRC1/CD68 ratio is positively associated with adipose tissue lipogenesis and with muscle mitochondrial gene expression in humans
Q35043710The adaptor protein APPL1 increases glycogen accumulation in rat skeletal muscle through activation of the PI3-kinase signalling pathway
Q34921325The evolution of insulin resistance in muscle of the glucose infused rat
Q91260359Total adiponectin is associated with incident cardiovascular and renal events in treated hypertensive patients: subanalysis of the ATTEMPT-CVD randomized trial
Q33553662Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells

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