Sustained Intermittent Hypoxemia Induces Adiponectin Oligomers Redistribution and a Tissue-Specific Modulation of Adiponectin Receptor in Mice

Sustained Intermittent Hypoxemia Induces Adiponectin Oligomers Redistribution and a Tissue-Specific Modulation of Adiponectin Receptor in Mice is …
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scholarly articleQ13442814

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P356DOI10.3389/FPHYS.2019.00068
P932PMC publication ID6376175
P698PubMed publication ID30800074

P2093author name stringAlexandre Legrand
Karim Zouaoui Boudjeltia
Alexandra Tassin
Mélany Pierard
Stéphanie Conotte
P2860cites workDevelopment of insulin resistance through sprouting of inflammatory markers during hypoxia in 3T3-L1 adipocytes and amelioration with curcumin.Q50904357
Endocytosis of adiponectin receptor 1 through a clathrin- and Rab5-dependent pathway.Q53873686
Loss of HIF-1α impairs GLUT4 translocation and glucose uptake by the skeletal muscle cells.Q54369425
MicroRNA-218 targets adiponectin receptor 2 to regulate adiponectin signaling.Q55068344
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actionsQ57249776
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Adiponectin oligomerization state and adiponectin receptors airway expression in chronic obstructive pulmonary diseaseQ61041501
Effect of chronic hypoxia on leptin, insulin, adiponectin, and ghrelinQ81668799
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Sialic acid modification of adiponectin is not required for multimerization or secretion but determines half-life in circulationQ24310524
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Adiponectin resistance in skeletal muscle: pathophysiological implications in chronic heart failureQ26745026
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Diaphragm Muscle Adaptation to Sustained Hypoxia: Lessons from Animal Models with Relevance to High Altitude and Chronic Respiratory DiseasesQ28066535
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A new device to mimic intermittent hypoxia in miceQ30455636
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Chronic hypoxia increases insulin-stimulated glucose uptake in mouse soleus muscleQ34502139
Intermittent hypoxemia and OSA: implications for comorbiditiesQ34840423
Hypoxemia in patients with COPD: cause, effects, and disease progressionQ35023212
Adiponectin-AdipoR1/2-APPL1 signaling axis suppresses human foam cell formation: differential ability of AdipoR1 and AdipoR2 to regulate inflammatory cytokine responsesQ35785437
Adiponectin receptors form homomers and heteromers exhibiting distinct ligand binding and intracellular signaling propertiesQ36579485
Hypoxia-inducible factor 1α regulates a SOCS3-STAT3-adiponectin signal transduction pathway in adipocytes.Q36596160
Effect of chronic intermittent hypoxia on triglyceride uptake in different tissues.Q36709586
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Chronic intermittent hypoxia induces atherosclerosis via activation of adipose angiopoietin-like 4.Q37186987
Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseasesQ37366361
Interactions of exercise training and high-fat diet on adiponectin forms and muscle receptors in miceQ37390991
Effects of varying degrees of intermittent hypoxia on proinflammatory cytokines and adipokines in rats and 3T3-L1 adipocytesQ37500257
Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function.Q37573701
Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasisQ37662940
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Adiponectin receptors: a review of their structure, function and how they workQ38177918
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Molecular mechanism of moderate insulin resistance in adiponectin-knockout miceQ38291409
Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese miceQ38299555
Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulationQ38303256
Obesity hypoventilation syndrome: current theories of pathogenesisQ38590371
Intermittent hypoxia training in prediabetes patients: Beneficial effects on glucose homeostasis, hypoxia tolerance and gene expressionQ38652332
Cardiovascular Adiponectin Resistance: The Critical Role of Adiponectin Receptor Modification.Q38687619
Hypoxia and the modulation of the actin cytoskeleton - emerging interrelationsQ38989120
An Emerging Role for Tubulin Isotypes in Modulating Cancer Biology and Chemotherapy ResistanceQ39414846
Hypoxia up-regulates glyceraldehyde-3-phosphate dehydrogenase in mouse brain capillary endothelial cells: involvement of Na+/Ca2+ exchangerQ40671269
Reference genes for expression studies in hypoxia and hyperglycemia models in human umbilical vein endothelial cellsQ41996061
Globular adiponectin resistance develops independently of impaired insulin-stimulated glucose transport in soleus muscle from high-fat-fed ratsQ42170113
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxiaQ42512319
Characterization of the inflammatory and metabolic profile of adipose tissue in a mouse model of chronic hypoxiaQ42712221
Hypoxia in 3T3-L1 adipocytes suppresses adiponectin expression via the PERK and IRE1 unfolded protein responseQ42797735
Intermittent hypoxia suppresses adiponectin secretion by adipocytesQ42811612
Prevalence and prediction of exercise-induced oxygen desaturation in patients with chronic obstructive pulmonary diseaseQ45216717
Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapyQ45729224
Adiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed ratsQ46202689
Inhibition of microRNA-218 reduces HIF-1α by targeting on Robo1 in mice aortic endothelial cells under intermittent hypoxiaQ47111060
Chronic Intermittent Hypoxia Impairs Insulin Sensitivity but Improves Whole-Body Glucose Tolerance by Activating Skeletal Muscle AMPK.Q47688256
Intermittent hypoxia in obese Zucker rats: cardiometabolic and inflammatory effects.Q47799206
Oxidative stress and nerve function after cardiopulmonary bypass in patients with diabetesQ47808355
Chronic intermittent hypoxia leads to insulin resistance and impaired glucose tolerance through dysregulation of adipokines in non-obese ratsQ47991092
Isolated nocturnal desaturation in COPD: prevalence and impact on quality of life and sleepQ48438342
Chronic intermittent hypoxia predisposes to liver injuryQ48473495
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectanimal modelQ264024
oligomerQ726004
hypoxemiaQ1479485
AdiponectinQ58809294
COPDQ20764290
P304page(s)68
P577publication date2019-01-01
P1433published inFrontiers in PhysiologyQ2434141
P1476titleSustained Intermittent Hypoxemia Induces Adiponectin Oligomers Redistribution and a Tissue-Specific Modulation of Adiponectin Receptor in Mice
P478volume10

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