Slow fusion pore expansion creates a unique reaction chamber for co-packaged cargo

scientific article

Slow fusion pore expansion creates a unique reaction chamber for co-packaged cargo is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1085/JGP.201711842
P932PMC publication ID5694939
P698PubMed publication ID28882880

P50authorDaniel AxelrodQ88473018
Ronald W HolzQ90028777
Kevin P BohannonQ96235786
Daniel A. LawrenceQ39600113
P2093author name stringMary A Bittner
P2860cites workProcessing of chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretionQ40735839
Tissue plasminogen activator (t-PA) is targeted to the regulated secretory pathway. Catecholamine storage vesicles as a reservoir for the rapid release of t-PA.Q41133880
Transient transfection studies of secretion in bovine chromaffin cells and PC12 cells. Generation of kainate-sensitive chromaffin cells.Q41552954
Polarized TIRFM reveals changes in plasma membrane topology before and during granule fusionQ42201429
Localization and regulation of the tissue plasminogen activator-plasmin system in the hippocampus.Q43918819
Protonation state of a single histidine residue contributes significantly to the kinetics of the reaction of plasminogen activator inhibitor-1 with tissue-type plasminogen activatorQ44807445
Matrix-degrading enzymes tissue plasminogen activator and matrix metalloprotease-3 in the hypothalamo-neurohypophysial systemQ46693077
Influence of the Alu-repeat I/D polymorphism in t-PA gene intron 8 on the stimulated t-PA release after venous occlusionQ48028278
Recapture after exocytosis causes differential retention of protein in granules of bovine chromaffin cells.Q50796308
Increased plasminogen activator inhibitor results in a hypofibrinolytic state in adolescents with obesity: in vivo and ex vivo evidence.Q51630897
Evidence that the H+ electrochemical gradient across membranes of chromaffin granules is not involved in exocytosisQ71766795
Serpin-protease complexes are trapped as stable acyl-enzyme intermediatesQ71823584
Identification of eight novel single-nucleotide polymorphisms at human tissue-type plasminogen activator (t-PA) locus: association with vascular t-PA release in vivoQ74225970
Plasminogen activator inhibitor-1 contains a cryptic high affinity binding site for the low density lipoprotein receptor-related proteinQ74299355
Resolution of Michaelis complex, acylation, and conformational change steps in the reactions of the serpin, plasminogen activator inhibitor-1, with tissue plasminogen activator and trypsinQ74552310
Selective recapture of secretory granule components after full collapse exocytosis in neuroendocrine chromaffin cellsQ85109926
A cost-effective approach to microporate mammalian cells with the Neon Transfection SystemQ85216644
NIH Image to ImageJ: 25 years of image analysisQ23319322
Patterns of synaptic activity in neural networks recorded by light emission from synaptolucinsQ28307290
The anti-fibrinolytic SERPIN, plasminogen activator inhibitor 1 (PAI-1), is targeted to and released from catecholamine storage vesiclesQ28579043
Proteomics. Tissue-based map of the human proteomeQ29617248
Localized topological changes of the plasma membrane upon exocytosis visualized by polarized TIRFM.Q33643745
Lumenal protein within secretory granules affects fusion pore expansionQ33990912
Carbocyanine dye orientation in red cell membrane studied by microscopic fluorescence polarizationQ34254410
Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeabilityQ34443186
Structure-function relationships of plasminogen activator inhibitor-1 and its potential as a therapeutic agentQ34693493
Post-fusion structural changes and their roles in exocytosis and endocytosis of dense-core vesicles.Q34713448
Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells.Q34763388
A new role for the dynamin GTPase in the regulation of fusion pore expansionQ35011226
Protein mobility within secretory granulesQ35775194
A nibbling mechanism for clathrin-mediated retrieval of secretory granule membrane after exocytosisQ36725018
LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.Q37333802
Update on intravenous recombinant tissue plasminogen activator for acute ischemic strokeQ38207776
Structure-function studies of the SERPIN plasminogen activator inhibitor type 1. Analysis of chimeric strained loop mutantsQ38338256
Tissue plasminogen activatorQ39605345
Unique secretory dynamics of tissue plasminogen activator and its modulation by plasminogen activator inhibitor-1 in vascular endothelial cellsQ39929087
Mechanisms of dense core vesicle recapture following "kiss and run" ("cavicapture") exocytosis in insulin-secreting cellsQ40522071
Stability characterization and formulation development of alteplase, a recombinant tissue plasminogen activatorQ40665888
P4510describes a project that usesImageJQ1659584
P433issue10
P304page(s)921-934
P577publication date2017-09-07
P1433published inThe Journal of General PhysiologyQ1092259
P1476titleSlow fusion pore expansion creates a unique reaction chamber for co-packaged cargo
P478volume149

Reverse relations

cites work (P2860)
Q48359379Chemistry in a vesicle.
Q90028784Chromogranin A, the major lumenal protein in chromaffin granules, controls fusion pore expansion
Q89715497Synaptotagmin-7 enhances calcium-sensing of chromaffin cell granules and slows discharge of granule cargos
Q89110786The fusion pore, 60 years after the first cartoon
Q55239707The synaptotagmin C2B domain calcium-binding loops modulate the rate of fusion pore expansion.
Q91723384Unraveling the mechanisms of calcium-dependent secretion

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