Chromogranin A, the major lumenal protein in chromaffin granules, controls fusion pore expansion

scientific article published on 30 November 2018

Chromogranin A, the major lumenal protein in chromaffin granules, controls fusion pore expansion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1085/JGP.201812182
P932PMC publication ID6363410
P698PubMed publication ID30504267

P50authorDaniel AxelrodQ88473018
Prabhodh S AbbineniQ90028773
Ronald W HolzQ90028777
P2093author name stringMary A Bittner
P2860cites workThe chromogranin-secretogranin familyQ28185052
A palette of fluorescent proteins optimized for diverse cellular environmentsQ28647200
How proteins produce cellular membrane curvatureQ29618016
Membrane curvature controls dynamin polymerizationQ30493714
Localized topological changes of the plasma membrane upon exocytosis visualized by polarized TIRFM.Q33643745
Lumenal protein within secretory granules affects fusion pore expansionQ33990912
The fusion pores of Ca2+ -triggered exocytosisQ34037133
Distinct fusion properties of synaptotagmin-1 and synaptotagmin-7 bearing dense core granulesQ34081432
Fluorescent cargo proteins in pancreatic beta-cells: design determines secretion kinetics at exocytosisQ34188253
Carbocyanine dye orientation in red cell membrane studied by microscopic fluorescence polarizationQ34254410
Role of the synaptobrevin C terminus in fusion pore formationQ34276398
Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis.Q34305380
Currents through the fusion pore that forms during exocytosis of a secretory vesicleQ34397957
A structural role for the synaptobrevin 2 transmembrane domain in dense-core vesicle fusion poresQ34470858
Simultaneous electrical and optical measurements show that membrane fusion precedes secretory granule swelling during exocytosis of beige mouse mast cellsQ34605300
Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells.Q34763388
A new role for the dynamin GTPase in the regulation of fusion pore expansionQ35011226
Exocytotic fusion pores are composed of both lipids and proteinsQ36589148
The extended granin family: structure, function, and biomedical implicationsQ36666413
A nibbling mechanism for clathrin-mediated retrieval of secretory granule membrane after exocytosisQ36725018
The mystery of the fusion poreQ37013086
The molecular function of adrenal chromaffin granules: established facts and unresolved topicsQ39479340
Mechanisms of dense core vesicle recapture following "kiss and run" ("cavicapture") exocytosis in insulin-secreting cellsQ40522071
The disulfide-bonded loop of chromogranin B mediates membrane binding and directs sorting from the trans-Golgi network to secretory granulesQ41786528
Polarized TIRFM reveals changes in plasma membrane topology before and during granule fusionQ42201429
Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesiclesQ43787533
Identification of a novel sorting determinant for the regulated pathway in the secretory protein chromogranin A.Q44216719
Chromogranins A and B are key proteins in amine accumulation, but the catecholamine secretory pathway is conserved without themQ44482157
Slow fusion pore expansion creates a unique reaction chamber for co-packaged cargoQ46310573
The crucial role of chromogranins in storage and exocytosis revealed using chromaffin cells from chromogranin A null mouse.Q46681537
Chromogranin A, the major catecholamine storage vesicle soluble protein. Multiple size forms, subcellular storage, and regional distribution in chromaffin and nervous tissue elucidated by radioimmunoassay.Q47241345
Recapture after exocytosis causes differential retention of protein in granules of bovine chromaffin cells.Q50796308
Visualization of Membrane Pore in Live Cells Reveals a Dynamic-Pore Theory Governing Fusion and Endocytosis.Q53833435
Membrane curvature in synaptic vesicle fusion and beyond.Q55052659
The synaptotagmin C2B domain calcium-binding loops modulate the rate of fusion pore expansion.Q55239707
The composition of adrenal chromaffin granules: an assessment of controversial resultsQ67499091
Processing of chromogranin A within chromaffin granules starts at C- and N-terminal cleavage sitesQ68325569
Flux of catecholamines through chromaffin vesicles in cultured bovine adrenal medullary cellsQ71357649
Intracellular and extracellular processing of chromogranin A. Determination of cleavage sitesQ72563888
pH-dependent association of chromogranin A with secretory vesicle membrane and a putative membrane binding region of chromogranin AQ72871525
The fusion pore, 60 years after the first cartoonQ89110786
P4510describes a project that usesImageJQ1659584
P433issue2
P304page(s)118-130
P577publication date2018-11-30
P1433published inThe Journal of General PhysiologyQ1092259
P1476titleChromogranin A, the major lumenal protein in chromaffin granules, controls fusion pore expansion
P478volume151

Reverse relations

cites work (P2860)
Q89715497Synaptotagmin-7 enhances calcium-sensing of chromaffin cell granules and slows discharge of granule cargos
Q92659614Vesicle Shrinking and Enlargement Play Opposing Roles in the Release of Exocytotic Contents

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