| P50 | author | Julie D Atkin | Q62470182 |
| P2093 | author name string | Manal A Farg | |
| | Chew L Lau | |
| | Philip M Beart | |
| | Nicole Wallis | |
| | Ross D O'Shea | |
| P2860 | cites work | Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis | Q24299487 |
| | Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease | Q24621854 |
| | Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model | Q24631645 |
| | Misfolded CuZnSOD and amyotrophic lateral sclerosis | Q24683677 |
| | Primary glia expressing the G93A-SOD1 mutation present a neuroinflammatory phenotype and provide a cellular system for studies of glial inflammation | Q25256714 |
| | Astrocytes: biology and pathology | Q27490746 |
| | Overloading of stable and exclusion of unstable human superoxide dismutase-1 variants in mitochondria of murine amyotrophic lateral sclerosis models | Q28235353 |
| | Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants | Q28245736 |
| | Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons | Q28298056 |
| | Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis | Q28303406 |
| | Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis | Q28592161 |
| | ALS: a disease of motor neurons and their nonneuronal neighbors | Q29618000 |
| | Unraveling the mechanisms involved in motor neuron degeneration in ALS | Q29619073 |
| | Onset and progression in inherited ALS determined by motor neurons and microglia | Q29619515 |
| | Astrocytic dysfunction: insights on the role in neurodegeneration | Q33486844 |
| | Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1. | Q33723622 |
| | Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. | Q33768246 |
| | From Charcot to SOD1: mechanisms of selective motor neuron death in ALS. | Q33792977 |
| | Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). | Q34010341 |
| | Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis | Q48177170 |
| | Rapid activation of astrocyte-specific expression of GFAP-lacZ transgene by focal injury | Q48730215 |
| | Localization of a mutant SOD1 protein in E40K-heterozygous dogs: Implications for non-cell-autonomous pathogenesis of degenerative myelopathy. | Q51330585 |
| | Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosis. | Q51751501 |
| | SnapShot: Astrocytes in Health and Disease. | Q52150360 |
| | Advantages and Pitfalls in Experimental Models Of ALS | Q57661626 |
| | Lack of apoptosis in mice with ALS | Q60618606 |
| | Glutamate transporter gene expression in amyotrophic lateral sclerosis motor cortex | Q71053694 |
| | Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite | Q73829106 |
| | Excitatory amino acid transporter 1 and 2 immunoreactivity in the spinal cord in amyotrophic lateral sclerosis | Q74237337 |
| | Aggregates of mutant protein appear progressively in dendrites, in periaxonal processes of oligodendrocytes, and in neuronal and astrocytic perikarya of mice expressing the SOD1(G93A) mutation of familial amyotrophic lateral sclerosis | Q74297193 |
| | Low expression of GluR2 AMPA receptor subunit protein by human motor neurons | Q77324803 |
| | A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis | Q81078641 |
| | Motor neuron disease in vitro: the use of cultured motor neurons to study amyotrophic lateral sclerosis | Q34061059 |
| | Superoxide dismutase and the death of motoneurons in ALS. | Q34553806 |
| | Fragmentation of the Golgi apparatus induced by the overexpression of wild-type and mutant human tau forms in neurons | Q35087803 |
| | Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis | Q35094527 |
| | Astrocytes from familial and sporadic ALS patients are toxic to motor neurons | Q35206666 |
| | Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis | Q35518293 |
| | Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis | Q35617722 |
| | TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions | Q35928153 |
| | Transporters for L-glutamate: an update on their molecular pharmacology and pathological involvement | Q36052481 |
| | Genomic analysis of reactive astrogliosis | Q36344611 |
| | CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure | Q36499527 |
| | Molecular biology of amyotrophic lateral sclerosis: insights from genetics | Q36573336 |
| | Mechanisms of Disease: astrocytes in neurodegenerative disease | Q36658874 |
| | Amyotrophic lateral sclerosis models and human neuropathology: similarities and differences | Q37008443 |
| | Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS. | Q37087752 |
| | The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease | Q37589418 |
| | Multifaceted deaths orchestrated by mitochondria in neurones. | Q37596650 |
| | Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond | Q37642283 |
| | Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology | Q37959310 |
| | Cellular mechanisms of protein aggregate propagation | Q38056356 |
| | Significance of aberrant glial cell phenotypes in pathophysiology of amyotrophic lateral sclerosis | Q38913010 |
| | G37R SOD1 mutant alters mitochondrial complex I activity, Ca(2+) uptake and ATP production. | Q39578873 |
| | Recruitment of mitochondria into apoptotic signaling correlates with the presence of inclusions formed by amyotrophic lateral sclerosis-associated SOD1 mutations. | Q39910561 |
| | Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1. | Q40254780 |
| | Aberrantly increased hydrophobicity shared by mutants of Cu,Zn-superoxide dismutase in familial amyotrophic lateral sclerosis. | Q40409233 |
| | Astrocytes in amyotrophic lateral sclerosis: direct effects on motor neuron survival. | Q41874406 |
| | A Golgi fragmentation pathway in neurodegeneration | Q41918712 |
| | Regulation of glutamate transporters in astrocytes: evidence for a relationship between transporter expression and astrocytic phenotype | Q42472658 |
| | Transportable and non-transportable inhibitors of L-glutamate uptake produce astrocytic stellation and increase EAAT2 cell surface expression | Q43167771 |
| | Early excitability changes in lumbar motoneurons of transgenic SOD1G85R and SOD1G(93A-Low) mice | Q43261428 |
| | Astrocyte mGlu(2/3)-mediated cAMP potentiation is calcium sensitive: studies in murine neuronal and astrocyte cultures | Q44126398 |
| | Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice. | Q44605286 |
| | Expression of SOD1 G93A or wild-type SOD1 in primary cultures of astrocytes down-regulates the glutamate transporter GLT-1: lack of involvement of oxidative stress | Q44702930 |
| | Binding and transport of [3H](2S,4R)- 4-methylglutamate, a new ligand for glutamate transporters, demonstrate labeling of EAAT1 in cultured murine astrocytes | Q44782707 |
| | Absence of glial fibrillary acidic protein and vimentin prevents hypertrophy of astrocytic processes and improves post-traumatic regeneration. | Q44911153 |
| | The VPAC2 agonist peptide histidine isoleucine (PHI) up-regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1G93A) by inhibiting caspase-3 mediated inactivation of GLT-1a | Q45170678 |
| | Combined excitotoxic-oxidative stress and the concept of non-cell autonomous pathology of ALS: insights into motoneuron axonopathy and astrogliosis. | Q45998148 |
| | ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. | Q46135324 |
| | Oxidative and excitotoxic insults exert differential effects on spinal motoneurons and astrocytic glutamate transporters: Implications for the role of astrogliosis in amyotrophic lateral sclerosis | Q46459537 |
| | Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis | Q46980730 |
| | Effects of lipopolysaccharide on glial phenotype and activity of glutamate transporters: Evidence for delayed up-regulation and redistribution of GLT-1. | Q46985610 |
| | Altered excitability of motor neurons in a transgenic mouse model of familial amyotrophic lateral sclerosis. | Q47874345 |
| P433 | issue | 1 | |
| P921 | main subject | amyotrophic lateral sclerosis | Q206901 |
| | astrocyte | Q502961 |
| P304 | page(s) | 166-179 | |
| P577 | publication date | 2017-08-31 | |
| P1433 | published in | Neurochemical Research | Q15716728 |
| P1476 | title | SOD1 Mutations Causing Familial Amyotrophic Lateral Sclerosis Induce Toxicity in Astrocytes: Evidence for Bystander Effects in a Continuum of Astrogliosis | |
| P478 | volume | 43 | |