| scholarly article | Q13442814 |
| P356 | DOI | 10.1152/JN.00728.2004 |
| P8608 | Fatcat ID | release_awf5zaravja6tkdvropfyzokya |
| P698 | PubMed publication ID | 15774713 |
| P5875 | ResearchGate publication ID | 7959656 |
| P50 | author | John R. Huguenard | Q41662452 |
| P2093 | author name string | Xiaoming Jin | |
| David A Prince | |||
| P2860 | cites work | Hippocampal GABA transporter function in temporal-lobe epilepsy | Q59093542 |
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| Decreased hippocampal inhibition and a selective loss of interneurons in experimental epilepsy | Q28282728 | ||
| The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation | Q28296169 | ||
| Differential regulation of GABA release and neuronal excitability mediated by neuropeptide Y1 and Y2 receptors in rat thalamic neurons | Q28349234 | ||
| Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition | Q28513477 | ||
| Cl- uptake promoting depolarizing GABA actions in immature rat neocortical neurones is mediated by NKCC1 | Q28566006 | ||
| Sodium-potassium-chloride cotransport | Q33807206 | ||
| What is GABAergic inhibition? How is it modified in epilepsy? | Q34041405 | ||
| K-Cl cotransport: properties and molecular mechanism | Q34110131 | ||
| Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain | Q34224419 | ||
| Cation-chloride co-transporters in neuronal communication, development and trauma | Q35104788 | ||
| Regulation and Modulation of pH in the Brain | Q35541864 | ||
| Volume-sensitive K(+)/Cl(-) cotransport in rabbit erythrocytes. Analysis of the rate-limiting activation and inactivation events | Q36439008 | ||
| Long-lasting reduction of inhibitory function and gamma-aminobutyric acid type A receptor subunit mRNA expression in a model of temporal lobe epilepsy | Q37359532 | ||
| Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones | Q38179385 | ||
| Ionic basis of GABAA receptor channel function in the nervous system | Q40392683 | ||
| Bridging the cleft at GABA synapses in the brain | Q40397848 | ||
| gamma-Aminobutyric acid (GABA): a fast excitatory transmitter which may regulate the development of hippocampal neurones in early postnatal life | Q40556176 | ||
| Potassium channels in cultured bovine adrenal chromaffin cells | Q42034237 | ||
| Two different responses of hippocampal pyramidal cells to application of gamma-amino butyric acid | Q42473758 | ||
| GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain. | Q42497057 | ||
| Structural and functional alterations in rat corticospinal neurons after axotomy | Q42523826 | ||
| Enhanced but fragile inhibition in the dentate gyrus in vivo in the kainic acid model of temporal lobe epilepsy: a study using current source density analysis | Q43621043 | ||
| Cell-type-specific GABA responses and chloride homeostasis in the cortex and amygdala | Q43814489 | ||
| Postnatal maturation of Na+, K+, 2Cl- cotransporter expression and inhibitory synaptogenesis in the rat hippocampus: an immunocytochemical analysis | Q43889417 | ||
| Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene | Q43986241 | ||
| Synaptic activity in chronically injured, epileptogenic sensory-motor neocortex | Q44046124 | ||
| Amygdala kindling induces upregulation of mRNA for NKCC1, a Na(+), K(+)-2Cl(-) cotransporter, in the rat piriform cortex | Q44158914 | ||
| Regulation of Cl--HCO3- exchangers by cAMP-dependent protein kinase in adult rat hippocampal CA1 neurons | Q44249837 | ||
| Induction of NMDA and GABAA receptor-mediated Ca2+ oscillations with KCC2 mRNA downregulation in injured facial motoneurons | Q44336844 | ||
| Loss of interneurons innervating pyramidal cell dendrites and axon initial segments in the CA1 region of the hippocampus following pilocarpine-induced seizures. | Q44398501 | ||
| Relative contributions of passive equilibrium and active transport to the distribution of chloride in mammalian cortical neurons | Q46019939 | ||
| Postnatal maturation of the GABAergic system in rat neocortex | Q46084392 | ||
| Epileptogenesis in chronically injured cortex: in vitro studies | Q46094785 | ||
| Horizontal spread of synchronized activity in neocortex and its control by GABA-mediated inhibition | Q46227789 | ||
| Cellular and field potential properties of epileptogenic hippocampal slices | Q46917804 | ||
| Two inhibitory postsynaptic potentials, and GABAA and GABAB receptor-mediated responses in neocortex of rat and cat. | Q47944039 | ||
| Modulation of mammalian dendritic GABA(A) receptor function by the kinetics of Cl- and HCO3- transport | Q48129794 | ||
| Chronic neocortical epileptogenesis in vitro | Q48130343 | ||
| Tetrodotoxin prevents posttraumatic epileptogenesis in rats | Q48138876 | ||
| Separate activation of fast and slow inhibitory postsynaptic potentials in rat neocortex in vitro | Q48139972 | ||
| Cl-/HCO3- exchange function differs in adult and fetal rat hippocampal neurons | Q48266046 | ||
| On the mechanism of GABA-induced currents in cultured rat cortical neurons | Q48293510 | ||
| The role of bicarbonate in GABAA receptor-mediated IPSPs of rat neocortical neurones. | Q48297623 | ||
| Whole-cell voltage-clamp study of the fading of GABA-activated currents in acutely dissociated hippocampal neurons | Q48324702 | ||
| Ontogeny of cation-Cl- cotransporter expression in rat neocortex | Q48399352 | ||
| Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex. | Q48450597 | ||
| Use-dependent depression of IPSPs in rat hippocampal pyramidal cells in vitro. | Q48531550 | ||
| Developmental changes in KCC1, KCC2 and NKCC1 mRNAs in the rat cerebellum. | Q48558868 | ||
| Extracellular potassium activity during epileptogenesis. | Q48581275 | ||
| Expression of the Na-K-2Cl cotransporter is developmentally regulated in postnatal rat brains: a possible mechanism underlying GABA's excitatory role in immature brain. | Q48593744 | ||
| Differential impact of miniature synaptic potentials on the soma and dendrites of pyramidal neurons in vivo. | Q48622886 | ||
| Chronic focal neocortical epileptogenesis: does disinhibition play a role? | Q48710625 | ||
| The effects of kindling on GABA-Mediated inhibition in the dentate gyrus of the rat. I. Paired-pulse depression | Q48724013 | ||
| Disinhibited in vitro neocortical slices containing experimentally induced cortical dysplasia demonstrate hyperexcitability. | Q48775040 | ||
| Localizing 3H-GABA in Nerve Terminals of Rat Cerebral Cortex by Electron Microscopic Autoradiography | Q48846486 | ||
| Electrophysiological properties of neocortical neurons in vitro. | Q48869909 | ||
| EPILEPTIFORM SEIZURES FROM CHRONIC ISOLATED CORTEX. | Q51284820 | ||
| The electrical excitability of chronically isolated cortex studied by means of permanently implanted electrodes. | Q51295743 | ||
| Posttetanic excitation mediated by GABA(A) receptors in rat CA1 pyramidal neurons. | Q51545464 | ||
| Activity-dependent disinhibition. I. Repetitive stimulation reduces IPSP driving force and conductance in the hippocampus in vitro. | Q52425649 | ||
| Changes in the distribution and connectivity of interneurons in the epileptic human dentate gyrus | Q57500194 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2117-2126 | |
| P577 | publication date | 2005-04-01 | |
| P1433 | published in | Journal of Neurophysiology | Q1709863 |
| P1476 | title | Impaired Cl- extrusion in layer V pyramidal neurons of chronically injured epileptogenic neocortex | |
| P478 | volume | 93 |
| Q34468152 | A C-terminal domain in KCC2 confers constitutive K+-Cl- cotransport |
| Q48153979 | Activity-dependent intracellular chloride accumulation and diffusion controls GABA(A) receptor-mediated synaptic transmission |
| Q35335945 | Acute and chronic efficacy of bumetanide in an in vitro model of posttraumatic epileptogenesis |
| Q48170667 | Adenosine release during seizures attenuates GABAA receptor-mediated depolarization |
| Q26864916 | Adult cortical plasticity following injury: Recapitulation of critical period mechanisms? |
| Q35043611 | Alcohol abuse promotes changes in non-synaptic epileptiform activity with concomitant expression changes in cotransporters and glial cells |
| Q35147300 | Altered GABA signaling in early life epilepsies |
| Q45131461 | Altered chloride homeostasis removes synaptic inhibitory constraint of the stress axis |
| Q35242333 | Brain injury impairs dentate gyrus inhibitory efficacy |
| Q34016647 | Bumetanide, an NKCC1 antagonist, does not prevent formation of epileptogenic focus but blocks epileptic focus seizures in immature rat hippocampus |
| Q48287749 | CLC-3 chloride channels moderate long-term potentiation at Schaffer collateral-CA1 synapses |
| Q34959293 | Cation-chloride cotransporters in neuronal development, plasticity and disease |
| Q55265914 | Chloride Homeostasis in Neurons With Special Emphasis on the Olivocerebellar System: Differential Roles for Transporters and Channels. |
| Q37131793 | Chloride accumulation drives volume dynamics underlying cell proliferation and migration. |
| Q33991375 | Chloride regulation in the pain pathway |
| Q27335980 | Chronic Posttraumatic Epilepsy following Neocortical Undercut Lesion in Mice |
| Q39851821 | Chronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons through NKCC1 Upregulation |
| Q40579058 | Chronic cortical injury and epileptogensis: a possible role for intracellular chloride homeostasis |
| Q52899342 | Components of neuronal chloride transport in rat and human neocortex. |
| Q37680726 | Compromising KCC2 transporter activity enhances the development of continuous seizure activity. |
| Q34448117 | Computational modeling reveals dendritic origins of GABA(A)-mediated excitation in CA1 pyramidal neurons |
| Q38034465 | Cortical inhibition, pH and cell excitability in epilepsy: what are optimal targets for antiepileptic interventions? |
| Q36957940 | Developmental patterns in the regulation of chloride homeostasis and GABA(A) receptor signaling by seizures |
| Q30481101 | Disrupted dentate granule cell chloride regulation enhances synaptic excitability during development of temporal lobe epilepsy |
| Q48272472 | Early changes in KCC2 phosphorylation in response to neuronal stress result in functional downregulation. |
| Q33242164 | Enhanced excitatory synaptic connectivity in layer v pyramidal neurons of chronically injured epileptogenic neocortex in rats. |
| Q37383521 | Epilepsy following cortical injury: cellular and molecular mechanisms as targets for potential prophylaxis |
| Q31170860 | Excitatory and inhibitory synaptic connectivity to layer V fast-spiking interneurons in the freeze lesion model of cortical microgyria |
| Q35367801 | Focal cortical lesions induce bidirectional changes in the excitability of fast spiking and non fast spiking cortical interneurons |
| Q36157004 | Functional alterations in GABAergic fast-spiking interneurons in chronically injured epileptogenic neocortex |
| Q37902083 | Functional consequences of the disturbances in the GABA-mediated inhibition induced by injuries in the cerebral cortex |
| Q30484438 | GABA(A) receptor-mediated excitation in dissociated neurons from human hypothalamic hamartomas |
| Q48032757 | Gabapentin Prevents Progressive Increases in Excitatory Connectivity and Epileptogenesis Following Neocortical Trauma |
| Q59791349 | Giant Depolarizing Potentials Trigger Transient Changes in the Intracellular Cl Concentration in CA3 Pyramidal Neurons of the Immature Mouse Hippocampus |
| Q37173250 | How do seizures stop? |
| Q46092408 | Immature neurons and GABA networks may contribute to epileptogenesis in pediatric cortical dysplasia |
| Q34141541 | Increased excitatory synaptic input to granule cells from hilar and CA3 regions in a rat model of temporal lobe epilepsy |
| Q47126109 | Inhibitory or excitatory? Optogenetic interrogation of the functional roles of GABAergic interneurons in epileptogenesis |
| Q36133211 | Interneuronal calcium channel abnormalities in posttraumatic epileptogenic neocortex |
| Q48094985 | KCC2 Gates Activity-Driven AMPA Receptor Traffic through Cofilin Phosphorylation. |
| Q40094027 | KCC2 knockdown impairs glycinergic synapse maturation in cultured spinal cord neurons |
| Q45331093 | Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival |
| Q35190435 | Loss of cation-chloride cotransporter expression in preterm infants with white matter lesions: implications for the pathogenesis of epilepsy |
| Q58698270 | Mechanism of BDNF Modulation in GABAergic Synaptic Transmission in Healthy and Disease Brains |
| Q38286262 | Mechanisms of intrinsic epileptogenesis in human gelastic seizures with hypothalamic hamartoma |
| Q41826853 | Mild KCC2 Hypofunction Causes Inconspicuous Chloride Dysregulation that Degrades Neural Coding |
| Q42422779 | Modulation of chloride homeostasis by inflammatory mediators in dorsal root ganglion neurons |
| Q26829362 | Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2 |
| Q28277258 | NKCC1 transporter facilitates seizures in the developing brain |
| Q24630525 | NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents |
| Q34026277 | Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital. |
| Q35648474 | Neuronal plasticity and thalamocortical sleep and waking oscillations |
| Q47830941 | Neuroprotection by Propofol Post-Conditioning: Focus on PKMζ/KCC2 Pathway Activity. |
| Q40868967 | Neurosteroidogenesis is required for the physiological response to stress: role of neurosteroid-sensitive GABAA receptors |
| Q48428795 | Non-synaptic mechanisms that could be responsible for potential antiepileptic effects of omega-3 fatty acids |
| Q27005895 | Novel determinants of the neuronal Cl(-) concentration |
| Q42321485 | Optogenetic silencing strategies differ in their effects on inhibitory synaptic transmission |
| Q34547895 | Ovariectomy modulation of morphine analgesia of neuropathic pain is associated with the change of K(+)-Cl(-) cotransporter 2 protein level in spinal dorsal horn. |
| Q33788071 | Potassium dynamics in the epileptic cortex: new insights on an old topic |
| Q48438986 | Potentiation of cortical inhibition by visual deprivation. |
| Q33995360 | Presynaptic inhibitory terminals are functionally abnormal in a rat model of posttraumatic epilepsy |
| Q48408039 | Pro-Brain-Derived Neurotrophic Factor (proBDNF)-Mediated p75NTR Activation Promotes Depolarizing Actions of GABA and Increases Susceptibility to Epileptic Seizures |
| Q34758978 | Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures. |
| Q41991712 | Pyramidal cells accumulate chloride at seizure onset |
| Q24620659 | Raising cytosolic Cl- in cerebellar granule cells affects their excitability and vestibulo-ocular learning |
| Q33696859 | Reorganization of inhibitory synaptic circuits in rodent chronically injured epileptogenic neocortex. |
| Q41978151 | Selective changes in inhibition as determinants for limited hyperexcitability in the insular cortex of epileptic rats. |
| Q41810874 | Short-term ionic plasticity at GABAergic synapses |
| Q33315041 | Slow GABA(A) mediated synaptic transmission in rat visual cortex |
| Q47843109 | Synaptic basis for intense thalamocortical activation of feedforward inhibitory cells in neocortex |
| Q44440843 | Synaptic strength modulation after cortical trauma: a role in epileptogenesis |
| Q47560551 | Tenuous Inhibitory GABAergic Signaling in the Reticular Thalamus |
| Q38458935 | The K(+)-Cl(-) Cotransporter KCC2 and Chloride Homeostasis: Potential Therapeutic Target in Acute Central Nervous System Injury. |
| Q43138216 | The K+-Cl cotransporter KCC2 promotes GABAergic excitation in the mature rat hippocampus |
| Q28511194 | The RCC1 domain of protein associated with Myc (PAM) interacts with and regulates KCC2 |
| Q36601929 | Transition from Initial Hypoactivity to Hyperactivity in Cortical Layer V Pyramidal Neurons after Traumatic Brain Injury In Vivo |
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