Long-term consumption of saponins derived from Platycodi radix (22 years old) enhances hepatic insulin sensitivity and glucose-stimulated insulin secretion in 90 % pancreatectomized diabetic rats fed a high-fat diet

scientific article published on 25 June 2008

Long-term consumption of saponins derived from Platycodi radix (22 years old) enhances hepatic insulin sensitivity and glucose-stimulated insulin secretion in 90 % pancreatectomized diabetic rats fed a high-fat diet is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1017/S000711450801218X
P698PubMed publication ID18577298

P2093author name stringSunmin Park
Young Seob Kim
Sang Mee Hong
Dae Yeon Kwon
P2860cites workPrevention of fat-induced insulin resistance by salicylateQ28345600
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Mechanism of impaired glucose-potentiated insulin secretion in diabetic 90% pancreatectomy rats. Study using glucagonlike peptide-1 (7-37).Q37351295
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Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistanceQ41785858
Platycodin D and D3 increase airway mucin release in vivo and in vitro in rats and hamstersQ43933822
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Decrease in glucose-stimulated insulin secretion with aging is independent of insulin action.Q44745161
Estrogen and exercise may enhance beta-cell function and mass via insulin receptor substrate 2 induction in ovariectomized diabetic ratsQ46613276
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Prolonged decrease of adipocyte size after rosiglitazone treatment in high- and low-fat-fed ratsQ46857137
SREBPs suppress IRS-2-mediated insulin signalling in the liverQ47868873
Effect of dietary Platycodon grandiflorum on the improvement of insulin resistance in obese Zucker rats.Q51552538
Long-term consumption of fermented soybean-derived Chungkookjang enhances insulinotropic action unlike soybeans in 90% pancreatectomized diabetic rats.Q53581551
IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes.Q53878797
In vivo insulin resistance induced by amylin primarily through inhibition of insulin-stimulated glycogen synthesis in skeletal muscle.Q54296728
Muscle GLUT 4 protein levels and impaired triglyceride metabolism in streptozotocin diabetic rats. Effect of a high sucrose diet and fish oil supplementationQ72228697
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Platycodi radix affects lipid metabolism in mice with high fat diet-induced obesityQ73128490
Aqueous extract isolated from Platycodon grandiflorum elicits the release of nitric oxide and tumor necrosis factor-alpha from murine macrophagesQ74022724
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunctionQ74191142
Saponins from platycodi radix ameliorate high fat diet-induced obesity in miceQ74578841
P433issue3
P304page(s)358-366
P577publication date2008-06-25
P1433published inBritish Journal of NutritionQ4970206
P1476titleLong-term consumption of saponins derived from Platycodi radix (22 years old) enhances hepatic insulin sensitivity and glucose-stimulated insulin secretion in 90 % pancreatectomized diabetic rats fed a high-fat diet
P478volume101

Reverse relations

cites work (P2860)
Q47141031Codonopsis lanceolata Water Extract Increases Hepatic Insulin Sensitivity in Rats with Experimentally-Induced Type 2 Diabetes
Q92503910Enzymatic Biotransformation of Balloon Flower Root Saponins into Bioactive Platycodin D by Deglucosylation with Caldicellulosiruptor bescii β-Glucosidase
Q38102732Plant-based foods as a source of lipotropes for human nutrition: a survey of in vivo studies
Q42806768Platyconic acid, a saponin from Platycodi radix, improves glucose homeostasis by enhancing insulin sensitivity in vitro and in vivo
Q46955366Protective effect of the roots extract of Platycodon grandiflorum on bile duct ligation-induced hepatic fibrosis in rats.

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