Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs.

scientific article published in June 2005

Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1211/0022357056118
P698PubMed publication ID15969931

P50authorTsutomu NakamuraQ57023886
P2093author name stringToshiro Niwa
Katsuhiko Okumura
Toshiyuki Sakaeda
Kohshi Nishiguchi
Noboru Okamura
Mikio Kakumoto
Koichi Iwaki
Jiang-shu Jin
Mika Nishikawa
P2860cites workIn vitro activation of 7-benzyloxyresorufin O-debenzylation and nifedipine oxidation in human liver microsomesQ44534145
Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover studyQ44832013
In vitro evaluation of cytochrome P450-mediated drug interactions between cytarabine, idarubicin, itraconazole and caspofunginQ44941953
Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimeticsQ46055776
Interaction between fluconazole and midazolam in intensive care patients.Q51458169
Effect of route of administration of fluconazole on the interaction between fluconazole and midazolam.Q51553057
Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents.Q51562990
Echinocandin antifungal drugsQ29398696
Prediction of drug-drug interactions of zonisamide metabolism in humans from in vitro dataQ32061089
Transporter-Enzyme Interactions: Implications for Predicting Drug-Drug Interactions from In Vitro DataQ33193683
Effects of the antifungal agents on oxidative drug metabolism: clinical relevanceQ33858325
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitorsQ34065800
Active secretion and enterocytic drug metabolism barriers to drug absorptionQ34190323
Antifungal agents: mechanisms of actionQ34208354
Comparative effects of the antimycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporin by human liver microsomesQ34359090
Genetic polymorphisms of the human MDR1 drug transporterQ34931160
Role of P-glycoprotein in pharmacokinetics: clinical implicationsQ35029495
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.Q35048738
Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugsQ35164664
Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevanceQ35642041
Fluconazole, but not terbinafine, enhances the effects of triazolam by inhibiting its metabolismQ36093518
Natural history of opportunistic disease in an HIV-infected urban clinical cohortQ39420529
Voriconazole inhibition of the metabolism of tacrolimus in a liver transplant recipient and in human liver microsomesQ39652863
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.Q40449494
Rapid assessment of P-glycoprotein inhibition and induction in vitroQ40639122
Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expressionQ40716924
Simvastatin and lovastatin, but not pravastatin, interact with MDR1.Q40743825
HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.Q42060921
Interaction of triazolam and ketoconazole in P-glycoprotein-deficient miceQ42464794
Interaction of digoxin with antihypertensive drugs via MDR1.Q42518658
Microsomal protein concentration modifies the apparent inhibitory potency of CYP3A inhibitorsQ44217892
P433issue6
P921main subjectmultiple drug resistanceQ643839
P304page(s)759-764
P577publication date2005-06-01
P1433published inJournal of Pharmacy and PharmacologyQ10532762
P1476titleEffect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs
P478volume57

Reverse relations

cites work (P2860)
Q36290698A review of clinical experience with newer antifungals in children
Q48238550Analysis of the variable factors influencing tacrolimus blood concentration during the switch from continuous intravenous infusion to oral administration after allogeneic hematopoietic stem cell transplantation.
Q53544619Azole antifungal inhibition of buprenorphine, methadone and oxycodone in vitro metabolism.
Q38015710Azole interactions with multidrug therapy in pediatric oncology
Q28273738Comparison of echinocandin antifungals
Q59285092Design and Antimicrobial Evaluation of 1-Methylimidazole Derivatives as New Antifungal and Antibacterial Agents
Q33390377Drug interaction between itraconazole and bortezomib: exacerbation of peripheral neuropathy and thrombocytopenia induced by bortezomib
Q43108275Effects of multiple oral dosing of itraconazole on the pharmacokinetics of cyclosporine in cats
Q36458402Emerging echinocandins for treatment of invasive fungal infections
Q38825266Evaluation of the effect of fluconazole on the pharmacokinetics of cyclosporin A in healthy dogs after a single dose and at steady-state
Q40164902Haloperidol is an inhibitor but not substrate for MDR1/P-glycoprotein
Q37904672Has the era of individualised medicine arrived for antifungals? A review of antifungal pharmacogenomics.
Q42038812Homology modeling and docking studies on oxidosqualene cyclases associated with primary and secondary metabolism of Centella asiatica
Q38462784Impact of special patient populations on the pharmacokinetics of echinocandins.
Q34058209In vitro and in vivo evidence for amphotericin B as a P-glycoprotein substrate on the blood-brain barrier
Q34211108In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats
Q40746038Inhibitory Potential of Antifungal Drugs on ATP-Binding Cassette Transporters P-Glycoprotein, MRP1 to MRP5, BCRP, and BSEP.
Q64131246Interacciones farmacológicas en el paciente crítico. ¿Un factor relevante para usar micafungina?
Q90645513Kinetics of Cyclophosphamide Metabolism in Humans, Dogs, Cats, and Mice and Relationship to Cytotoxic Activity and Pharmacokinetics
Q35026516Micafungin in the treatment of invasive candidiasis and invasive aspergillosis
Q36895679Micafungin sodium, the second of the echinocandin class of antifungals: theory and practice
Q37288766Micafungin: a review of its use in adults for the treatment of invasive and oesophageal candidiasis, and as prophylaxis against Candida infections
Q38053482Micafungin: a review of its use in the prophylaxis and treatment of invasive Candida infections
Q37535957Micafungin: a review of its use in the prophylaxis and treatment of invasive Candida infections in pediatric patients
Q34197425Modeling chemical interaction profiles: II. Molecular docking, spectral data-activity relationship, and structure-activity relationship models for potent and weak inhibitors of cytochrome P450 CYP3A4 isozyme
Q37377752Recent approaches to antifungal therapy for invasive mycoses.
Q42111914Role of plasma proteins in pharmacokinetics of micafungin, an antifungal antibiotic, in analbuminemic rats
Q37827883Safety of micafungin in infants: insights into optimal dosing
Q42868963Systemic uptake of miconazole during vaginal suppository use and effect on CYP1A2 and CYP3A4 associated enzyme activities in women
Q36828156The echinocandin micafungin: a review of the pharmacology, spectrum of activity, clinical efficacy and safety
Q36626518The echinocandins: comparison of their pharmacokinetics, pharmacodynamics and clinical applications
Q37331953The enzymatic basis of drug-drug interactions with systemic triazole antifungals.
Q46224687Use of micafungin versus fluconazole for antifungal prophylaxis in neutropenic patients receiving hematopoietic stem cell transplantation
Q52780226Vincristine toxicity with co-administration of fluconazole during induction therapy for pediatric acute lymphoblastic leukemia.
Q46000239[Micafungin for therapy of invasive candidiasis in solid organ transplant recipients].

Search more.