Phosphorylation and degradation of αB-crystallin during enterovirus infection facilitates viral replication and induces viral pathogenesis

scientific article published on 19 August 2017

Phosphorylation and degradation of αB-crystallin during enterovirus infection facilitates viral replication and induces viral pathogenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.20366
P932PMC publication ID5650377
P698PubMed publication ID29088822

P2093author name stringGabriel Fung
Honglin Luo
Yasir Mohamud
Jerry Wong
Yuan Chao Xue
Feaven Berhe
P2860cites workalphaB-crystallin: a novel p53-target gene required for p53-dependent apoptosisQ39792344
Proteasome inhibition attenuates coxsackievirus-induced myocardial damage in miceQ39976598
Dysferlin deficiency confers increased susceptibility to coxsackievirus-induced cardiomyopathyQ41161957
Biochemical and mechanical dysfunction in a mouse model of desmin-related myopathyQ41826353
Dominant-negative function of the C-terminal fragments of NBR1 and SQSTM1 generated during enteroviral infectionQ42221994
Cleavage of sequestosome 1/p62 by an enteroviral protease results in disrupted selective autophagy and impaired NFKB signalingQ42273359
AlphaB-crystallin interacts with intermediate filaments in response to stressQ42833212
The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturationQ43556597
Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosisQ44306740
Roles for αB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse modelQ44639137
Phosphorylation of alphaB-crystallin alters chaperone function through loss of dimeric substructureQ44875494
Phosphorylation and translocation of heat shock protein 27 and alphaB-crystallin in human myocardium after cardioplegia and cardiopulmonary bypassQ46892971
Small heat shock proteins and protection against ischemic injury in cardiac myocytesQ46972878
Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and diseaseQ47756415
Ischemia-induced phosphorylation and translocation of stress protein alpha B-crystallin to Z lines of myocardium.Q48014059
Phosphorylation of alphaB-crystallin in mitotic cells and identification of enzymatic activities responsible for phosphorylation.Q52183272
Phosphorylation of alphaB-crystallin in response to various types of stress.Q52191790
CRYAB and HSPB2 deficiency increases myocyte mitochondrial permeability transition and mitochondrial calcium uptake.Q53624149
Restrictive Cardiomyopathy, Atrioventricular Block and Mild to Subclinical Myopathy in Patients With Desmin-Immunoreactive Material DepositsQ58911267
Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arraysQ73306462
Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in miceQ74147604
AlphaB-crystallin modulates protein aggregation of abnormal desminQ79203032
MyocarditisQ87230906
A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathyQ24311671
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activityQ27860643
Alpha B-crystallin suppresses pressure overload cardiac hypertrophyQ28571805
Abundance and location of the small heat shock proteins HSP25 and alphaB-crystallin in rat and human heartQ28573782
Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failureQ28579532
Ischemia-induced association of the stress protein alpha B-crystallin with I-band portion of cardiac titinQ28583343
Production of a dominant-negative fragment due to G3BP1 cleavage contributes to the disruption of mitochondria-associated protective stress granules during CVB3 infectionQ30009523
Transgene overexpression of alphaB crystallin confers simultaneous protection against cardiomyocyte apoptosis and necrosis during myocardial ischemia and reperfusionQ31825986
A genome-based resource for molecular cardiovascular medicine: toward a compendium of cardiovascular genes.Q32161221
Dystrophin deficiency markedly increases enterovirus-induced cardiomyopathy: a genetic predisposition to viral heart diseaseQ34138862
Proteasome activator REGgamma enhances coxsackieviral infection by facilitating p53 degradationQ34190751
Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in miceQ34231667
Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathyQ34442070
Alpha B-crystallin in cardiac tissue. Association with actin and desmin filamentsQ34466918
Cleavage of serum response factor mediated by enteroviral protease 2A contributes to impaired cardiac functionQ35732935
Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosisQ35971521
Antiapoptotic properties of α-crystallin-derived peptide chaperones and characterization of their uptake transporters in human RPE cellsQ36784092
Protein quality control and degradation in cardiomyocytesQ36952213
Kinetics of the translocation and phosphorylation of alphaB-crystallin in mouse heart mitochondria during ex vivo ischemiaQ37200174
Build it up-Tear it down: protein quality control in the cardiac sarcomereQ37313697
Protein degradation systems in viral myocarditis leading to dilated cardiomyopathyQ37541537
Proteotoxicity and cardiac dysfunction--Alzheimer's disease of the heart?Q38077849
Proteotoxicity and cardiac dysfunctionQ38497014
Cardiomyocyte expression of a polyglutamine preamyloid oligomer causes heart failure.Q38846039
Ubiquitin-dependent proteolysis of cyclin D1 is associated with coxsackievirus-induced cell growth arrestQ39698538
Cytoplasmic translocation, aggregation, and cleavage of TDP-43 by enteroviral proteases modulate viral pathogenesisQ39743300
P4510describes a project that usesImageJQ1659584
P433issue43
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)74767-74780
P577publication date2017-08-19
P1433published inOncotargetQ1573155
P1476titlePhosphorylation and degradation of αB-crystallin during enterovirus infection facilitates viral replication and induces viral pathogenesis
P478volume8

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Q93087198Small heat shock protein CRYAB inhibits intestinal mucosal inflammatory responses and protects barrier integrity through suppressing IKKβ activitycites workP2860

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