Mismatch repair regulates homologous recombination, but has little influence on antigenic variation, in Trypanosoma brucei

scientific article

Mismatch repair regulates homologous recombination, but has little influence on antigenic variation, in Trypanosoma brucei is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M308123200
P698PubMed publication ID12933800

P2093author name stringRichard McCulloch
Joanna S Bell
P2860cites workA phylogenomic study of the MutS family of proteinsQ24548238
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The Saccharomyces cerevisiae Msh2 mismatch repair protein localizes to recombination intermediates in vivo.Q27935147
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Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cellsQ28209896
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MSH2 deficient mice are viable and susceptible to lymphoid tumoursQ28508486
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Mismatch repair in replication fidelity, genetic recombination, and cancer biologyQ29616483
Molecular cloning and characterization of the DNA mismatch repair gene class 2 from the Trypanosoma cruziQ30996863
DNA double-strand break repairQ33757109
Homeologous recombination and mismatch repair during transformation in Streptococcus pneumoniae: saturation of the Hex mismatch repair systemQ33883002
Trypanosoma brucei variant surface glycoprotein regulation involves coupled activation/inactivation and chromatin remodeling of expression sitesQ33890790
Suppression of gene amplification and chromosomal DNA integration by the DNA mismatch repair systemQ33941481
Control and function of the bloodstream variant surface glycoprotein expression sites in Trypanosoma brucei.Q33945337
Predominance of duplicative VSG gene conversion in antigenic variation in African trypanosomesQ33959039
Roles for mismatch repair factors in regulating genetic recombinationQ34057743
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DNA mismatch repair and genetic instabilityQ34090778
An update on antigenic variation in African trypanosomesQ34292113
Molecular mechanisms of DNA mismatch repairQ34293069
The Mre11 complex: at the crossroads of dna repair and checkpoint signallingQ34623788
Antigenic variation and the African trypanosome genomeQ35093072
Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAsQ35163740
Inactivation of mismatch repair overcomes the barrier to transduction between Salmonella typhimurium and Salmonella typhiQ36105804
Altered replication and inverted repeats induce mismatch repair-independent recombination between highly diverged DNAs in yeast.Q36565513
Dual roles for DNA sequence identity and the mismatch repair system in the regulation of mitotic crossing-over in yeastQ36574453
Mismatch repair and the fidelity of genetic recombinationQ38730984
Parameters controlling the rate of gene targeting frequency in the protozoan parasite LeishmaniaQ39721568
Gene conversions mediating antigenic variation in Trypanosoma brucei can occur in variant surface glycoprotein expression sites lacking 70-base-pair repeat sequencesQ40020905
Molecular basis for trypanosome antigenic variationQ40265766
A role for RAD51 and homologous recombination in Trypanosoma brucei antigenic variationQ40445788
Regulation of vsg expression site transcription and switching in Trypanosoma bruceiQ41758638
Control of variant surface glycoprotein gene-expression sites in Trypanosoma bruceiQ42680578
Mismatch repair and the regulation of phase variation in Neisseria meningitidisQ43612705
Ku is important for telomere maintenance, but not for differential expression of telomeric VSG genes, in African trypanosomesQ43937107
Inactivation of Mre11 does not affect VSG gene duplication mediated by homologous recombination in Trypanosoma brucei.Q43993843
Surface epitope variation via mosaic gene formation is potential key to long-term survival of Trypanosoma bruceiQ45178379
Two pathways of homologous recombination in Trypanosoma bruceiQ46247501
Homologous recombination between the tuf genes of Salmonella typhimurium.Q47826625
Targeting of exogenous DNA into Trypanosoma brucei requires a high degree of homology between donor and target DNA.Q48066413
The identification of circular extrachromosomal DNA in the nuclear genome of Trypanosoma bruceiQ48266263
Genetic analysis of the mouse brain proteomeQ48651123
The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutantsQ50192890
Dependence on RAD52 and RAD1 for anticancer drug resistance mediated by inactivation of mismatch repair genes.Q54108643
Dual recognition–incision enzymes might be involved in mismatch repair and meiosisQ57272811
A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma bruceiQ58846342
Insertions, deletions and mismatches in heteroduplex DNA made by recA proteinQ70179308
Polymerase chain reaction-based gene disruption in Trypanosoma bruceiQ73535928
In vivo epitope tagging of Trypanosoma brucei genes using a one step PCR-based strategyQ73630950
Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma bruceiQ73739230
Arabidopsis MutS homologs-AtMSH2, AtMSH3, AtMSH6, and a novel AtMSH7-form three distinct protein heterodimers with different specificities for mismatched DNAQ73893732
Non-homologous end joining as a mechanism of DNA repairQ74185601
Mismatch repair: praying for genome stabilityQ74387016
P433issue46
P407language of work or nameEnglishQ1860
P921main subjectTrypanosoma bruceiQ33244
DNA mismatch repairQ2984243
P304page(s)45182-45188
P577publication date2003-08-21
P1433published inJournal of Biological ChemistryQ867727
P1476titleMismatch repair regulates homologous recombination, but has little influence on antigenic variation, in Trypanosoma brucei
P478volume278

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cites work (P2860)
Q30506471Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species
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Q59805089Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes
Q33273750From silent genes to noisy populations-dialogue between the genotype and phenotypes of antigenic variation
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Q24535964MSH2 is essential for the preservation of genome integrity and prevents homeologous recombination in the moss Physcomitrella patens
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Q34189677Overview of DNA Repair in Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major
Q38870864RNA polymerase I transcription stimulates homologous recombination in Trypanosoma brucei.
Q37603116Recombinant protein expression in Leishmania tarentolae
Q33632168TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei
Q36158447Targeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategy
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Q24646998Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination
Q94564173Trypanosoma brucei and Trypanosoma cruzi DNA Mismatch Repair Proteins Act Differently in the Response to DNA Damage Caused by Oxidative Stress
Q28757482Trypanosoma brucei homologous recombination is dependent on substrate length and homology, though displays a differential dependence on mismatch repair as substrate length decreases
Q35124994Trypanosoma cruzi MSH2: Functional analyses on different parasite strains provide evidences for a role on the oxidative stress response.

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