| scholarly article | Q13442814 |
| P2093 | author name string | Zhang Y | |
| Wu R | |||
| Fahy JV | |||
| Hyde DM | |||
| Hotchkiss JA | |||
| Ferrando R | |||
| Wong HH | |||
| Novikov A | |||
| Ordoñez CL | |||
| Dolganov G | |||
| Khashayar R | |||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | asthma | Q35869 |
| P304 | page(s) | 517-523 | |
| P577 | publication date | 2001-02-01 | |
| P1433 | published in | American Journal of Respiratory and Critical Care Medicine | Q4744267 |
| P1476 | title | Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression | |
| P478 | volume | 163 |
| Q40302231 | A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma. |
| Q54565102 | A deficient TLR2 signaling promotes airway mucin production in Mycoplasma pneumoniae-infected allergic mice. |
| Q36203213 | A morphometric study of mucins and small airway plugging in cystic fibrosis. |
| Q28590394 | ADAM8: a new therapeutic target for asthma |
| Q36176909 | AGR2 is induced in asthma and promotes allergen-induced mucin overproduction. |
| Q37250330 | Abr, a negative regulator of Rac, attenuates cockroach allergen-induced asthma in a mouse model |
| Q57966293 | Acute Allergen-Induced Airway Remodeling in Atopic Asthma |
| Q36539588 | Acute inflammation induces insulin-like growth factor-1 to mediate Bcl-2 and Muc5ac expression in airway epithelial cells. |
| Q37516982 | Advances in mucous cell metaplasia: a plug for mucus as a therapeutic focus in chronic airway disease |
| Q88090665 | Aerosolized montelukast polymeric particles-an alternative to oral montelukast-alleviate symptoms of asthma in a rodent model |
| Q90644701 | Airway Epithelial Cell Peroxisome Proliferator-Activated Receptor γ Regulates Inflammation and Mucin Expression in Allergic Airway Disease |
| Q28082284 | Airway Gland Structure and Function |
| Q48217556 | Airway Mucus and Asthma: The Role of MUC5AC and MUC5B. |
| Q37256057 | Airway epithelial cells: current concepts and challenges. |
| Q36488742 | Airway epithelial miRNA expression is altered in asthma. |
| Q35219741 | Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation |
| Q36858419 | Airway epithelium in atopic and nonatopic asthma: similarities and differences |
| Q46861382 | Airway goblet cell hyperplasia in asthma: hypersecretory and anti-inflammatory? |
| Q34442431 | Airway mucus obstruction: mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia |
| Q36369409 | Airway mucus: From production to secretion. |
| Q47845487 | Airway remodelling in asthma: models and supermodels? |
| Q38048279 | Airway smooth muscle as a target in asthma and the beneficial effects of bronchial thermoplasty |
| Q42622139 | Allelic association and recombination hotspots in the mucin gene (MUC) complex on chromosome 11p15.5. |
| Q37447096 | Allergic asthma biomarkers using systems approaches |
| Q33588011 | Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation |
| Q33757070 | An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure |
| Q36001230 | Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics |
| Q34449739 | Anti-inflammatory effects of the R2 peptide, an inhibitor of transglutaminase 2, in a mouse model of allergic asthma, induced by ovalbumin |
| Q36282984 | Are mouse models of asthma appropriate for investigating the pathogenesis of airway hyper-responsiveness? |
| Q35183809 | Asthma deaths; persistent and preventable mortality |
| Q34550135 | Asthma, airway biology, and nasal disorders in AJRCCM 2001. |
| Q94564218 | Asthma: A Loss of Post-natal Homeostatic Control of Airways Smooth Muscle With Regression Toward a Pre-natal State |
| Q90277597 | BMS‑345541 inhibits airway inflammation and epithelial‑mesenchymal transition in airway remodeling of asthmatic mice |
| Q93120112 | Bitter Taste Receptors: an Answer to Comprehensive Asthma Control? |
| Q94076955 | Brg1通过STAT6促进哮喘气道黏液高分泌 |
| Q38170952 | Bronchial thermoplasty: interventional therapy in asthma |
| Q36342946 | Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction |
| Q38085109 | Cellular and molecular biology of airway mucins |
| Q36013719 | Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 5' elements |
| Q24298786 | Characterization of ciliated bronchial epithelium 1, a ciliated cell-associated gene induced during mucociliary differentiation |
| Q55155504 | Chemokine expression in the early response to injury in human airway epithelial cells. |
| Q36482653 | Chronic exposure to beta-blockers attenuates inflammation and mucin content in a murine asthma model |
| Q38791607 | Chronic inflammatory airway diseases: the central role of the epithelium revisited |
| Q42560001 | Chronic intermittent mechanical stress increases MUC5AC protein expression |
| Q54542221 | Cigarette smoke induces growth differentiation factor 15 production in human lung epithelial cells: implication in mucin over-expression. |
| Q41537548 | Clarithromycin Suppresses Chloride Channel Accessory 1 and Inhibits Interleukin-13-Induced Goblet Cell Hyperplasia in Human Bronchial Epithelial Cells |
| Q44966446 | Clarithromycin inhibits interleukin-13-induced goblet cell hyperplasia in human airway cells |
| Q44486010 | Clarithromycin inhibits overproduction of muc5ac core protein in murine model of diffuse panbronchiolitis |
| Q35603132 | Clinical and laboratory studies of the fate of intranasal allergen |
| Q36330548 | Complement C3a regulates Muc5ac expression by airway Clara cells independently of Th2 responses |
| Q42108234 | Composition of the immunoglobulin classic antigen-binding site regulates allergic airway inflammation in a murine model of experimental asthma. |
| Q89339031 | Conjunctival cytologic features in patients with unilateral primary acquired nasolacrimal duct obstruction |
| Q37431918 | Control of lung defence by mucins and macrophages: ancient defence mechanisms with modern functions |
| Q47818177 | Corticosteroid and long-acting ß-agonist therapy reduces epithelial goblet cell metaplasia. |
| Q41960313 | Cough and Asthma |
| Q42451048 | DNA synthesis and Bcl-2 expression during development of mucous cell metaplasia in airway epithelium of rats exposed to LPS. |
| Q47106615 | Death Receptor 3 regulates distinct pathological attributes of acute versus chronic murine allergic lung inflammation. |
| Q36207811 | Decrease in airway mucous gene expression caused by treatment with anti-tumor necrosis factor alpha in a murine model of allergic asthma |
| Q54528175 | Depletion of CD8+ T cells enhances airway remodelling in a rodent model of asthma. |
| Q38319656 | Dexamethasone-mediated repression of MUC5AC gene expression in human lung epithelial cells |
| Q35855718 | Dietary n-3 fatty acids have suppressive effects on mucin upregulation in mice infected with Pseudomonas aeruginosa |
| Q42289045 | Differences in respiratory syncytial virus and influenza infection in a house-dust-mite-induced asthma mouse model: consequences for steroid sensitivity |
| Q43757287 | Differential properties of mucous glycoproteins in rat nasal epithelium. A comparison between allergic inflammation and lipopolysaccharide stimulation |
| Q46413344 | Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma |
| Q36482627 | Disease-specific gene expression profiling in multiple models of lung disease |
| Q95301626 | Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium |
| Q34658887 | Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma. |
| Q33808911 | Does Inhalation of Virgin Coconut Oil Accelerate Reversal of Airway Remodelling in an Allergic Model of Asthma? |
| Q35012026 | Does remodelling of the airway wall precede asthma? |
| Q90053659 | EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice |
| Q48786886 | Early life allergen-induced mucus overproduction requires augmented neural stimulation of pulmonary neuroendocrine cell secretion. |
| Q45122329 | Effect of MMP/ADAM inhibitors on goblet cell hyperplasia in cultured human bronchial epithelial cells |
| Q44179176 | Effect of combining salmeterol and fluticasone on the progression of airway remodeling |
| Q46736177 | Effect of disodium cromoglycate on airway mucus secretion during antigen-induced late asthmatic responses in a murine model of asthma |
| Q47718384 | Effect of suplatast tosilate on goblet cell metaplasia in patients with asthma |
| Q40271861 | Effects of corticosteroid-induced apoptosis on airway epithelial wound closure in vitro |
| Q89610629 | Effects of dexamethasone on VEGF-induced MUC5AC expression in human primary bronchial epithelial cells: Implications for asthma |
| Q51689613 | Effects of regular treatment with combination of salmeterol/fluticasone propionate and salmeterol alone in cough variant asthma. |
| Q58049795 | Effects of the Histone Deacetylase Inhibitor, Trichostatin A, in a Chronic Allergic Airways Disease Model in Mice |
| Q64277586 | Emerging Regulatory Roles of Dual-Specificity Phosphatases in Inflammatory Airway Disease |
| Q44493348 | Endobronchial biopsy: a guide for asthma therapy selection in the era of bronchial thermoplasty |
| Q57966296 | Eosinophils in repair and remodelling |
| Q42066750 | Epidermal growth factor receptor activation by epidermal growth factor mediates oxidant-induced goblet cell metaplasia in human airway epithelium |
| Q35688187 | Epinephrine Activation of the β2-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells |
| Q26799074 | Epithelial Sodium and Chloride Channels and Asthma |
| Q30441389 | Epithelial cell proliferation contributes to airway remodeling in severe asthma |
| Q57705949 | Erythromycin attenuates MUC5AC synthesis and secretion in cultured human tracheal cells infected with RV14 |
| Q91823466 | Escalating Mucus Inhibition to the Top of Our Priorities |
| Q50435670 | Etiology of epithelial barrier dysfunction in patients with type 2 inflammatory diseases |
| Q53556182 | Evaluation of cytokine mRNA in induced sputum from patients with allergic rhinitis: relationship to airway hyperresponsiveness. |
| Q51721201 | Expression of respiratory mucins in fatal status asthmaticus and mild asthma. |
| Q50639647 | Expression of the proapoptotic protein Bax is reduced in bronchial mucous cells of asthmatic subjects. |
| Q93091835 | Fungi in Mucoobstructive Airway Diseases |
| Q34960273 | Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways |
| Q34479395 | Genetics and early detection in idiopathic pulmonary fibrosis |
| Q35219883 | Glandular gene expression of sinus mucosa in chronic rhinosinusitis with and without cystic fibrosis |
| Q36539631 | Glucocorticoid receptor and histone deacetylase-2 mediate dexamethasone-induced repression of MUC5AC gene expression |
| Q64229892 | HSP90 inhibitor geldanamycin reverts IL-13- and IL-17-induced airway goblet cell metaplasia |
| Q93120623 | Heterogeneity of Pulmonary Stem Cells |
| Q40108954 | Histamine induces MUC5AC expression via a hCLCA1 pathway |
| Q39343736 | Histamine regulates mucin expression through H1 receptor in airway epithelial cells |
| Q48098566 | Horses With Pasture Asthma Have Airway Remodeling That Is Characteristic of Human Asthma. |
| Q35830069 | How can microarrays unlock asthma? |
| Q40633405 | Human Airway Trypsin-Like Protease Increases Mucin Gene Expression in Airway Epithelial Cells |
| Q39149977 | Human airway trypsin-like protease, a serine protease involved in respiratory diseases |
| Q43177938 | Hyaluronan fragments/CD44 mediate oxidative stress-induced MUC5B up-regulation in airway epithelium. |
| Q24683878 | IL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin production |
| Q36537810 | IL-13 induces a bronchial epithelial phenotype that is profibrotic |
| Q37707600 | IL-1β induction of MUC5AC gene expression is mediated by CREB and NF-κB and repressed by dexamethasone |
| Q37695423 | IL-33 stimulates CXCL8/IL-8 secretion in goblet cells but not normally differentiated airway cells |
| Q34538145 | IL-4 induced MUC4 enhancement in respiratory epithelial cells in vitro is mediated through JAK-3 selective signaling |
| Q41696575 | IL-4-induced caveolin-1-containing lipid rafts aggregation contributes to MUC5AC synthesis in bronchial epithelial cells |
| Q33350176 | Identification of a common gene expression response in different lung inflammatory diseases in rodents and macaques. |
| Q47887170 | Identification of trans Protein QTL for Secreted Airway Mucins in Mice and a Causal Role for Bpifb1. |
| Q38821078 | Idiopathic Pulmonary Fibrosis: A Genetic Disease That Involves Mucociliary Dysfunction of the Peripheral Airways |
| Q47652881 | Immunohistochemical analyses of MUC5AC mucin expression in sinus mucosa of children with sinusitis and controls |
| Q33350872 | Immunological and genetic aspects of asthma and allergy. |
| Q37084506 | Immunology of asthma and chronic obstructive pulmonary disease |
| Q30399215 | Impacts of allergic airway inflammation on lung pathology in a mouse model of influenza A virus infection |
| Q35670429 | In vivo uptake of inhaled particles by airway phagocytes is enhanced in patients with mild asthma compared with normal volunteers |
| Q54579894 | Induced trefoil factor family 1 expression by trans-differentiating Clara cells in a murine asthma model. |
| Q38887480 | Induction of MUC5AC mucin expression by histamine through the activation of its core promoter region |
| Q34588958 | Inhibiting pollen reduced nicotinamide adenine dinucleotide phosphate oxidase-induced signal by intrapulmonary administration of antioxidants blocks allergic airway inflammation |
| Q42498010 | Inhibition of IL-13-induced periostin in airway epithelium attenuates cellular protein expression of MUC5AC. |
| Q37793998 | Innate immune responses of the airway epithelium. |
| Q54390453 | Interleukin-13 induces mucin 5AC production involving STAT6/SPDEF in human airway epithelial cells. |
| Q46634305 | Interleukin-9 induces mucous cell metaplasia independent of inflammation |
| Q46703569 | Involvement of the p38 MAPK pathway in IL-13-induced mucous cell metaplasia in mouse tracheal epithelial cells |
| Q57795389 | Localization of Secretory Mucins MUC5AC and MUC5B in Normal/Healthy Human Airways |
| Q37651351 | Low-molecular-weight heparin (LMWH)-loaded large porous PEG-PLGA particles for the treatment of asthma |
| Q33699462 | Lung epithelial stem cells and their niches: Fgf10 takes center stage |
| Q37232960 | Luteolin Attenuates Airway Mucus Overproduction via Inhibition of the GABAergic System |
| Q34180777 | MARCKS-related peptide modulates in vivo the secretion of airway Muc5ac |
| Q40131321 | MUC5AC and a Glycosylated Variant of MUC5B Alter Mucin Composition in Children With Acute Asthma. |
| Q83576311 | Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells |
| Q37247147 | Mechanisms of airway hyperresponsiveness in asthma |
| Q39655373 | Mechanisms of remodeling in asthmatic airways |
| Q35557799 | Methods for the assessment of endobronchial biopsies in clinical research: application to studies of pathogenesis and the effects of treatment |
| Q36385668 | Methylomic markers of persistent childhood asthma: a longitudinal study of asthma-discordant monozygotic twins |
| Q37424310 | Modulation of conjunctival goblet cell function by inflammatory cytokines |
| Q45985404 | Modulation of the allergic asthma transcriptome following resiquimod treatment. |
| Q94921992 | More Than Just a Barrier: The Immune Functions of the Airway Epithelium in Asthma Pathogenesis |
| Q28589969 | Muc5b is required for airway defence |
| Q50487696 | Mucin expression in peripheral airways of patients with chronic obstructive pulmonary disease. |
| Q36437203 | Mucin gene expression in rhinitis syndromes. |
| Q35103876 | Mucin production during prenatal and postnatal murine lung development |
| Q58696935 | Mucins: the frontline defence of the lung |
| Q34481949 | Mucoactive drugs for asthma and COPD: any place in therapy? |
| Q46680643 | Mucociliary clearance in patients with chronic asthma: effects of beta agonists |
| Q37259129 | Mucus hypersecretion in asthma: causes and effects |
| Q36482261 | Murine cytomegalovirus influences Foxj1 expression, ciliogenesis, and mucus plugging in mice with allergic airway disease |
| Q36178176 | NAD(P)H quinone oxidoreductase 1 regulates neutrophil elastase-induced mucous cell metaplasia |
| Q47684437 | NO2 inhalation enhances asthma susceptibility in a rat model |
| Q58798935 | Neuropeptides in asthma, chronic obstructive pulmonary disease and cystic fibrosis |
| Q47951767 | Neutrophil elastase induces mucus cell metaplasia in mouse lung |
| Q94526044 | Nicotine-Free e-Cigarette Vapor Exposure Stimulates IL6 and Mucin Production in Human Primary Small Airway Epithelial Cells |
| Q39240987 | PMA stimulates MUC5B gene expression through an Sp1-based mechanism in airway epithelial cells |
| Q41925077 | Pathogenesis of mucous cell metaplasia in a murine asthma model |
| Q47791593 | Physicochemical properties of mucus and their impact on transmucosal drug delivery |
| Q36202835 | Protein kinase C delta regulates airway mucin secretion via phosphorylation of MARCKS protein |
| Q44942929 | Reduced airway inflammation and remodeling in parallel with mucin 5AC protein expression decreased by s-carboxymethylcysteine, a mucoregulant, in the airways of rats exposed to sulfur dioxide |
| Q44982131 | Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs |
| Q24200353 | Regular treatment with formoterol for chronic asthma: serious adverse events |
| Q24241250 | Regular treatment with formoterol for chronic asthma: serious adverse events |
| Q24241960 | Regular treatment with salmeterol for chronic asthma: serious adverse events |
| Q51650555 | Regulation of MUC5AC mucin secretion and airway surface liquid metabolism by IL-1β in human bronchial epithelia |
| Q36216587 | Regulation of airway mucin gene expression |
| Q40428482 | Regulation of sialyl-Lewis x epitope expression by TNF-alpha and EGF in an airway carcinoma cell line |
| Q34457559 | Remodeling of the airway epithelium in asthma |
| Q45642387 | Respiratory syncytial virus in allergic lung inflammation increases Muc5ac and gob-5. |
| Q38030757 | Response to infections in patients with asthma and atopic disease: an epiphenomenon or reflection of host susceptibility? |
| Q47895692 | Reversibility of airway inflammation and remodelling following cessation of antigenic challenge in a model of chronic asthma. |
| Q36103376 | Role of MUC5AC in the pathogenesis of exercise-induced bronchoconstriction |
| Q40007869 | Role of epidermal growth factor receptor in maintaining airway goblet cell hyperplasia in rats sensitized to allergen |
| Q26829473 | Role of epithelial mucins during airway infection |
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| Q51338556 | Runx2, a novel regulator for goblet cell differentiation and asthma development. |
| Q38979965 | S100A8, S100A9 and S100A12 activate airway epithelial cells to produce MUC5AC via extracellular signal-regulated kinase and nuclear factor-κB pathways |
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| Q58574008 | Sex-specific airway hyperreactivity and sex-specific transcriptome remodeling in neonatal piglets challenged with intra-airway acid |
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| Q64122230 | Sialylation of MUC4β N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with type-2 inflammation |
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| Q90229721 | Stem cell-based Lung-on-Chips: The best of both worlds? |
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| Q46476974 | Submucosal gland cells in human lower airways produce MUC5AC protein |
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| Q38055384 | The pharmacological modulation of allergen-induced asthma. |
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