A novel in vivo role for osteoprotegerin ligand in activation of monocyte effector function and inflammatory response

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A novel in vivo role for osteoprotegerin ligand in activation of monocyte effector function and inflammatory response is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M403968200
P698PubMed publication ID15145935

P50authorIqbal S GrewalQ100761370
P2093author name stringHua Wang
Wyne P Lee
Jed Ross
Dhaya Seshasayee
Richard Carano
Peter Gribling
Nicholas Van Bruggen
P2860cites workCD40 AND CD154 IN CELL-MEDIATED IMMUNITYQ22255634
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cellsQ24315251
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
RANK is essential for osteoclast and lymph node developmentQ24598872
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
The TNF and TNF receptor superfamilies: integrating mammalian biologyQ28203717
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
CD40 signaling of monocyte inflammatory cytokine synthesis through an ERK1/2-dependent pathway. A target of interleukin (il)-4 and il-10 anti-inflammatory actionQ28609312
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligandQ29619331
Mitogen-activated protein kinases: specific messages from ubiquitous messengersQ30303652
Assessment of rheumatoid arthritis using a modified scoring method on digitized and original radiographsQ32015794
Osteoprotegerin ligand: a common link between osteoclastogenesis, lymph node formation and lymphocyte development.Q33611312
Development and maturation of secondary lymphoid tissues.Q33652498
The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.Q33823576
Apoptosis in human autoimmune diseasesQ33836352
Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progressionQ33944735
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.Q34469691
TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factorQ36380989
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolismQ37108966
Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesinQ37629829
RANKing the importance of measles virus in Paget's diseaseQ40326890
The many roles of CD40 in cell-mediated inflammatory responsesQ41203088
The proto-oncogene Bcl-2 and its role in regulating apoptosisQ41492030
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γQ59064307
P433issue29
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
P1104number of pages8
P304page(s)30202-30209
P577publication date2004-05-15
P1433published inJournal of Biological ChemistryQ867727
P1476titleA novel in vivo role for osteoprotegerin ligand in activation of monocyte effector function and inflammatory response
P478volume279

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cites work (P2860)
Q36493751Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model
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Q39002838Cell Signaling Pathways That Regulate Antigen Presentation
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Q37767159Do RANKL inhibitors (denosumab) affect inflammation and immunity?
Q37441693Effects of RANKL-Targeted Therapy in Immunity and Cancer
Q48261321ICOS-Ligand Triggering Impairs Osteoclast Differentiation and Function In Vitro and In Vivo
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Q37727115RANKL enhances macrophage paracrine pro-calcific activity in high phosphate-treated smooth muscle cells: dependence on IL-6 and TNF-α.
Q47133428RANKL-mediated harmonious dialogue between fetus and mother guarantees smooth gestation by inducing decidual M2 macrophage polarization
Q34993353Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages.
Q35689812Safety and tolerability of denosumab for the treatment of postmenopausal osteoporosis
Q36591727TGF-beta1 on osteoimmunology and the bone component cells
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Q86025548Zoledronate but not denosumab suppresses macrophagic differentiation of THP-1 cells. An aetiologic model of bisphosphonate-related osteonecrosis of the jaw (BRONJ)

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