Mutagenic PCR.

scientific article published in June 1994

Mutagenic PCR. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/GR.3.6.S136
P698PubMed publication ID7920233

P2093author name stringG F Joyce
R C Cadwell
P433issue6
P304page(s)S136-40
P577publication date1994-06-01
P1433published inGenome ResearchQ5533485
P1476titleMutagenic PCR
P478volume3

Reverse relations

cites work (P2860)
Q51278089A divalent cation-dependent variant of the glmS ribozyme with stringent Ca2+ selectivity co-opts a preexisting nonspecific metal ion-binding site.
Q33428452A genotype-to-phenotype map of in vitro selected RNA-cleaving DNAzymes: implications for accessing the target phenotype
Q35813426A modular, bifunctional RNA that integrates itself into a target RNA.
Q28213193A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications
Q71353065Affinity maturation of phage-displayed peptide ligands
Q31963272An Escherichia coli expression assay and screen for human immunodeficiency virus protease variants with decreased susceptibility to indinavir
Q44544146An alcohol dehydrogenase ribozyme
Q33571381An evolved xylose transporter from Zymomonas mobilis enhances sugar transport in Escherichia coli
Q34139593An in vivo selection method to optimize trans-splicing ribozymes
Q46070825Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences.
Q39744801Analyzing partially randomized nucleic acid pools: straight dope on doping
Q30663736Applied molecular evolution of O6-benzylguanine-resistant DNA alkyltransferases in human hematopoietic cells
Q43821357Asn(78) and His(81) form a destabilizing locus within the Max HLH-LZ homodimer.
Q46917393Autoimmunity and tumor immunity induced by immune responses to mutations in self
Q33922569Biotechnology techniques for the development of new tumor specific peptides
Q30751852Chemical and biochemical strategies for the randomization of protein encoding DNA sequences: library construction methods for directed evolution
Q33450068Compensatory mutations in the L30e kink-turn RNA-protein complex.
Q36070050Cross Talk Inhibition Nullified by a Receiver Domain Missense Substitution
Q33983265Cyclic-di-GMP-mediated repression of swarming motility by Pseudomonas aeruginosa: the pilY1 gene and its impact on surface-associated behaviors
Q84131126Darwinian molecular imaging
Q91747052Directed Evolution of P450 BM3 towards Functionalization of Aromatic O-Heterocycles
Q28756069Directed evolution of Methanococcus jannaschii citramalate synthase for biosynthesis of 1-propanol and 1-butanol by Escherichia coli
Q30870894Directed evolution of a genetic circuit
Q36611228Directed evolution of a thermostable esterase.
Q36985743Directed evolution of ligand dependence: small-molecule-activated protein splicing
Q31056280Directed evolution of novel polymerase activities: mutation of a DNA polymerase into an efficient RNA polymerase
Q34417041Directed evolution of the forkhead-associated domain to generate anti-phosphospecific reagents by phage display
Q35101787Directed evolution of the substrate specificity of dialkylglycine decarboxylase
Q36377741Directed evolution to improve the catalytic efficiency of urate oxidase from Bacillus subtilis
Q33403245Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition
Q31152254Diversifying carotenoid biosynthetic pathways by directed evolution
Q34785463Dual requirement for rho and protein kinase C in direct activation of phospholipase D1 through G protein-coupled receptor signaling
Q41844344Effect of transition metal ions on the fluorescence and Taq-catalyzed polymerase chain reaction of tricyclic cytidine analogs
Q34162654Effects of a non-conservative sequence on the properties of β-glucuronidase from Aspergillus terreus Li-20
Q44759089Effects of mutations in the N terminal region of the yeast G protein alpha-subunit Gpa1p on signaling by pheromone receptors
Q31110532Efficient and high fidelity incorporation of dye-terminators by a novel archaeal DNA polymerase mutant
Q33221276Engineering of phenylacetaldehyde reductase for efficient substrate conversion in concentrated 2-propanol
Q33221271Enhanced reactivity of Rhizopus oryzae lipase displayed on yeast cell surfaces in organic solvents: potential as a whole-cell biocatalyst in organic solvents
Q27936093Establishing a role for the GTPase Ypt1p at the late Golgi
Q30497513Estimating the evidence of selection and the reliability of inference in unigenic evolution.
Q33344328Expanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx).
Q44331574Experimental evolution of a green fluorescent protein composed of 19 unique amino acids without tryptophan.
Q37253121FeoA and FeoC are essential components of the Vibrio cholerae ferrous iron uptake system, and FeoC interacts with FeoB.
Q43820583Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast
Q24523990Functional Cus1p is found with Hsh155p in a multiprotein splicing factor associated with U2 snRNA
Q33955668Functional genomics with protein-protein interactions
Q34528019Generating thermal stable variants of protein domains through phage display
Q24609793Generation of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffolds
Q32068528Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism
Q47316987Halogenated Ether, Alcohol, and Alkane Anesthetics Activate TASK-3 Tandem Pore Potassium Channels Likely through a Common Mechanism
Q33888941High affinity, developability and functional size: the holy grail of combinatorial antibody library generation.
Q27648583Identification of CD46 Binding Sites within the Adenovirus Serotype 35 Fiber Knob
Q42319067Identification of a Residue (Glu60) in TRAP Required for Inducing Efficient Transcription Termination at the trp Attenuator Independent of Binding Tryptophan and RNA.
Q46856565Identification of a glyphosate-resistant mutant of rice 5-enolpyruvylshikimate 3-phosphate synthase using a directed evolution strategy.
Q58737068Identification of novel sesquiterpene synthase genes that mediate the biosynthesis of valerianol, which was an unknown ingredient of tea
Q31089913Improvements to the Kunkel mutagenesis protocol for constructing primary and secondary phage-display libraries
Q30650758Improving enzymes for cancer gene therapy
Q34427599Improving the quality of industrially important enzymes by directed evolution
Q28215933In vitro display technologies: novel developments and applications
Q38821539In vitro evolution of coenzyme-independent variants from the glmS ribozyme structural scaffold
Q46629297In vitro evolution of randomized ribozymes
Q36019128In vitro flow cytometry-based screening platform for cellulase engineering.
Q24643887In vitro selection and evolution of functional proteins by using ribosome display
Q35384515In vivo elimination of parental clones in general and site-directed mutagenesis
Q41888497In vivo evolution of a catalytic RNA couples trans-splicing to translation
Q31121933In vivo selection of spectinomycin-binding RNAs
Q37132050Inactivation of the bacterial RNA polymerase due to acquisition of secondary structure by the ω subunit
Q92979194KnowVolution of the Polymer-Binding Peptide LCI for Improved Polypropylene Binding
Q27008422Library methods for structural biology of challenging proteins and their complexes
Q30882631Low free energy cost of very long loop insertions in proteins
Q37311367Low selection pressure aids the evolution of cooperative ribozyme mutations in cells
Q40938473Low-fidelity Pyrococcus furiosus DNA polymerase mutants useful in error-prone PCR.
Q24535964MSH2 is essential for the preservation of genome integrity and prevents homeologous recombination in the moss Physcomitrella patens
Q30707748Mapping of the minimal domain encoding a conformational epitope by lambda phage surface display: factor VIII inhibitor antibodies from haemophilia A patients
Q34070098Molecular breeding: the natural approach to protein design
Q58802662Multiplexed assays of variant effects contribute to a growing genotype-phenotype atlas
Q33255928Mutant library construction in directed molecular evolution: casting a wider net.
Q37545917Mutational analysis of the P1 phosphorylation domain in Escherichia coli CheA, the signaling kinase for chemotaxis.
Q30383961Mutations in Mtr4 Structural Domains Reveal Their Important Role in Regulating tRNAiMet Turnover in Saccharomyces cerevisiae and Mtr4p Enzymatic Activities In Vitro.
Q34631621Nickel(II) chelatase variants directly evolved from murine ferrochelatase: porphyrin distortion and kinetic mechanism
Q33641842Nucleic acid evolution and minimization by nonhomologous random recombination
Q36311987One face of a transmembrane helix is crucial in mechanosensitive channel gating
Q34456547Opposing effects of folding and assembly chaperones on evolvability of Rubisco
Q37617985Optimization models and the structure of the genetic code
Q36406869Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene Therapy
Q28201864Phage Display
Q31117519Phage display technology: clinical applications and recent innovations
Q30883495Phosphorylation of nucleosides by the mutated acid phosphatase from Morganella morganii
Q27695733Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability
Q34215858Protein selection using yeast surface display
Q33281713RNA mutagenesis yields highly diverse mRNA libraries for in vitro protein evolution
Q37401148RNA regulators responding to ribosomal protein S15 are frequent in sequence space
Q32062491Random mutagenesis of human estrogen receptor ligand binding domain identifies mutations that decrease sensitivity to estradiol and increase sensitivity to a diphenol indene-ol compound: basis for a regulatable expression system
Q30978579Rapid generation of incremental truncation libraries for protein engineering using alpha-phosphothioate nucleotides.
Q54563990Rapid identification of functionally critical amino acids in a G protein-coupled receptor.
Q31060379Recent advances in the in vitro evolution of nucleic acids
Q37059977Relationship between RNA Lariat Debranching and Ty1 Element Retrotransposition
Q36483417Retrotransposon target site selection by imitation of a cellular protein
Q31967754Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries.
Q64230215Role of SpaO in the assembly of the sorting platform of a Salmonella type III secretion system
Q30960966Selecting and evolving functional proteins in vitro by ribosome display
Q64109253Selection and analyses of variants of a designed protein suggest importance of hydrophobicity of partially buried sidechains for protein stability at high temperatures
Q30832417Selection-subtraction approach (SSA): a universal genetic screening technique that enables negative selection
Q31826132Selectively infective phage technology
Q40109633Semi-rational engineering of a coral fluorescent protein into an efficient highlighter
Q40695874Sequence saturation mutagenesis (SeSaM): a novel method for directed evolution
Q91964182Simultaneous Enhancement of Thermostability and Catalytic Activity of a Metagenome-Derived β-Glucosidase Using Directed Evolution for the Biosynthesis of Butyl Glucoside
Q24798108Site-specific genomic (SSG) and random domain-localized (RDL) mutagenesis in yeast
Q37287017SmpB contributes to reading frame selection in the translation of transfer-messenger RNA
Q35799445Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step
Q27679683Structural and Functional Studies on the Interaction of Adenovirus Fiber Knobs and Desmoglein 2
Q34056891Structure of the RNA polymerase assembly factor Crl and identification of its interaction surface with sigma S.
Q37346935Substrate ambiguous enzymes within the Escherichia coli proteome offer different evolutionary solutions to the same problem
Q37074216Synthetic control of a fitness tradeoff in yeast nitrogen metabolism
Q36639409TEM-1 beta-lactamase as a scaffold for protein recognition and assay
Q35813374Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I.
Q34070088Temperature adaptation of enzymes: lessons from laboratory evolution
Q56984526The NTP binding site of the polymerase ribozyme
Q42369901The Topology of the l-Arginine Exporter ArgO Conforms to an Nin-Cout Configuration in Escherichia coli: Requirement for the Cytoplasmic N-Terminal Domain, Functional Helical Interactions, and an Aspartate Pair for ArgO Function
Q27932211The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches
Q47900242The role of peptide modules in protein evolution
Q36573301The yeast nucleolar protein Cbf5p is involved in rRNA biosynthesis and interacts genetically with the RNA polymerase I transcription factor RRN3.
Q27655760Two Structurally Independent Domains of E. coli NusG Create Regulatory Plasticity via Distinct Interactions with RNA Polymerase and Regulators
Q42103470Variants of DsRed fluorescent protein: Development of a copper sensor.
Q31826513Yeast surface display for directed evolution of protein expression, affinity, and stability
Q33392699mKikGR, a monomeric photoswitchable fluorescent protein

Search more.