| scholarly article | Q13442814 |
| P2093 | author name string | Punit Marathe | |
| Sandeep Dutta | |||
| Patrick Poulin | |||
| Thierry Lavé | |||
| Handan He | |||
| Hannah M Jones | |||
| Malcolm Rowland | |||
| Jenny Y Chien | |||
| Ragini Vuppugalla | |||
| Christopher R Gibson | |||
| Kimberly K Adkison | |||
| Volker Fischer | |||
| Vikash K Sinha | |||
| James W T Yates | |||
| Barbara J Ring | |||
| M Sherry Ku | |||
| Thorir Björnsson | |||
| Rhys Do Jones | |||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pharmacokinetics | Q323936 |
| P1104 | number of pages | 16 | |
| P304 | page(s) | 4074-4089 | |
| P577 | publication date | 2011-03-30 | |
| P1433 | published in | Journal of Pharmaceutical Sciences | Q3186933 |
| P1476 | title | PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: comparative assessment of prediction methods of human volume of distribution | |
| P478 | volume | 100 |
| Q92392659 | An in vitro toolbox to accelerate anti-malarial drug discovery and development |
| Q39666574 | Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies |
| Q91484217 | Application of the Tissue Composition-Based Model to Minipig for Predicting the Volume of Distribution at Steady State and Dermis-to-Plasma Partition Coefficients of Drugs Used in the Physiologically Based Pharmacokinetics Model in Dermatology |
| Q31002556 | Assessment of chimeric mice with humanized livers in new drug development: generation of pharmacokinetics, metabolism and toxicity data for selecting the final candidate compound. |
| Q30576914 | Case studies for practical food effect assessments across BCS/BDDCS class compounds using in silico, in vitro, and preclinical in vivo data |
| Q42022291 | Characterization of preclinical in vitro and in vivo pharmacokinetics properties for KBP-7018, a new tyrosine kinase inhibitor candidate for treatment of idiopathic pulmonary fibrosis |
| Q88008504 | Comparing Mechanistic and Preclinical Predictions of Volume of Distribution on a Large Set of Drugs |
| Q39656097 | Comparison of in-vivo and in-silico methods used for prediction of tissue: plasma partition coefficients in rat. |
| Q51255318 | Correlation-based prediction of tissue-to-plasma partition coefficients using readily available input parameters. |
| Q38790679 | Deconvolution and IVIVC: Exploring the Role of Rate-Limiting Conditions |
| Q51139778 | Development of a decision tree to classify the most accurate tissue-specific tissue to plasma partition coefficient algorithm for a given compound. |
| Q36910606 | Dose selection based on physiologically based pharmacokinetic (PBPK) approaches |
| Q39248091 | Drug delivery trends in clinical trials and translational medicine: growth in biologic molecule development and impact on rheumatoid arthritis, Crohn's disease, and colitis |
| Q104500156 | Evaluation of Prediction Accuracy for Volume of Distribution in Rat and Human Using In Vitro, In Vivo, PBPK and QSAR Methods |
| Q89115461 | Food Effect Projections via Physiologically Based Pharmacokinetic Modeling: Predictive Case Studies |
| Q89523107 | Global Sensitivity Analysis of the Rodgers and Rowland Model for Prediction of Tissue: Plasma Partitioning Coefficients: Assessment of the Key Physiological and Physicochemical Factors That Determine Small-Molecule Tissue Distribution |
| Q41880361 | Human absorption, distribution, metabolism and excretion properties of drug molecules: a plethora of approaches |
| Q50055624 | Improved Human Pharmacokinetic Prediction of Hepatically Metabolized Drugs With Species-Specific Systemic Clearance. |
| Q99201826 | In silico models of human pk parameters. Prediction of volume of distribution using an extensive data set and a reduced number of parameters |
| Q34143314 | In vitro platforms for evaluating liver toxicity |
| Q39782124 | Mechanistic investigations into the species differences in pinometostat clearance: impact of binding to alpha-1-acid glycoprotein and permeability-limited hepatic uptake |
| Q35940544 | Microdosing and drug development: past, present and future |
| Q45805301 | Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability |
| Q43424784 | Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions |
| Q38072598 | Pharmacokinetics, pharmacodynamics and physiologically-based pharmacokinetic modelling of monoclonal antibodies |
| Q37974113 | Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs? |
| Q59793441 | Preclinical pharmacokinetic evaluation to facilitate repurposing of tyrosine kinase inhibitors nilotinib and imatinib as antiviral agents |
| Q41513317 | Preclinical pharmacokinetic/pharmacodynamic modeling and simulation in the pharmaceutical industry: an IQ consortium survey examining the current landscape |
| Q27902282 | Predicting volume of distribution with decision tree-based regression methods using predicted tissue:plasma partition coefficients |
| Q92168392 | Prediction Characteristics of Oral Absorption Simulation Software Evaluated Using Structurally Diverse Low-Solubility Drugs |
| Q38962990 | Prediction of Tissue-to-Plasma Ratios of Basic Compounds in Mice |
| Q85791328 | Prediction of drug disposition in diabetic patients by means of a physiologically based pharmacokinetic model |
| Q38086778 | Prediction of drug disposition on the basis of its chemical structure |
| Q51083254 | Prediction of drug distribution in rat and humans using an artificial neural networks ensemble and a PBPK model. |
| Q38010485 | Prediction of volume of distribution at steady state in humans: comparison of different approaches |
| Q40606599 | Quantifying and Communicating Uncertainty in Preclinical Human Dose-Prediction |
| Q38188659 | Vertical allometry: fact or fiction? |
Search more.