| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.XPHS.2018.05.024 |
| P698 | PubMed publication ID | 29906472 |
| P2093 | author name string | Filippos Kesisoglou | |
| Tycho Heimbach | |||
| Binfeng Xia | |||
| Neil Parrott | |||
| Christophe Tistaert | |||
| Tanay S Samant | |||
| P2860 | cites work | A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability | Q28293773 |
| Utility of physiologically based modeling and preclinical in vitro/in vivo data to mitigate positive food effect in a BCS class 2 compound | Q30662113 | ||
| Drug, meal and formulation interactions influencing drug absorption after oral administration. Clinical implications | Q33605319 | ||
| In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs | Q34061188 | ||
| Physiologically based absorption modelling to predict the impact of drug properties on pharmacokinetics of bitopertin | Q34099804 | ||
| BDDCS applied to over 900 drugs | Q34206152 | ||
| Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system | Q34403502 | ||
| The pharmacokinetics and bioavailability of a tracer dose of [3H]-mebendazole in man. | Q34622486 | ||
| The Role of CDK4/6 Inhibition in Breast Cancer | Q35586728 | ||
| Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption | Q37058658 | ||
| A review of drug solubility in human intestinal fluids: implications for the prediction of oral absorption. | Q38133189 | ||
| PBPK models for the prediction of in vivo performance of oral dosage forms | Q38141441 | ||
| Direct In Vivo Human Intestinal Permeability (Peff ) Determined with Different Clinical Perfusion and Intubation Methods | Q38269764 | ||
| Incorporation of the Time-Varying Postprandial Increase in Splanchnic Blood Flow into a PBPK Model to Predict the Effect of Food on the Pharmacokinetics of Orally Administered High-Extraction Drugs. | Q38773640 | ||
| Profiling and trend analysis of food effects on oral drug absorption considering micelle interaction and solubilization by bile micelles | Q39612238 | ||
| Predicting intestinal precipitation--a case example for a basic BCS class II drug | Q39846636 | ||
| Application of Physiologically Based Pharmacokinetic (PBPK) Modeling to Support Dose Selection: Report of an FDA Public Workshop on PBPK. | Q40606545 | ||
| Characterization of Human Duodenal Fluids in Fasted and Fed State Conditions. | Q40675687 | ||
| Gastrointestinal behavior of nano- and microsized fenofibrate: In vivo evaluation in man and in vitro simulation by assessment of the permeation potential | Q40907845 | ||
| Basic concepts in physiologically based pharmacokinetic modeling in drug discovery and development | Q41768726 | ||
| Role of physiological intestinal water in oral absorption | Q43117344 | ||
| Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid | Q43121950 | ||
| The pharmacokinetics and bioavailability of mebendazole in man: a pilot study using [3H]-mebendazole | Q43261606 | ||
| Predicting the effect of cytochrome P450 inhibitors on substrate drugs: analysis of physiologically based pharmacokinetic modeling submissions to the US Food and Drug Administration | Q45201599 | ||
| Ribociclib Bioavailability Is Not Affected by Gastric pH Changes or Food Intake: In Silico and Clinical Evaluations | Q46297172 | ||
| Physiologically based pharmacokinetic modelling to predict single- and multiple-dose human pharmacokinetics of bitopertin | Q46379587 | ||
| PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: comparative assessment of prediction methods of human volume of distribution | Q46873334 | ||
| Physiologically Based Pharmacokinetic Model Predictions of Panobinostat (LBH589) as a Victim and Perpetrator of Drug-Drug Interactions | Q47982766 | ||
| Validation of Dissolution Testing with Biorelevant Media: An OrBiTo Study. | Q48358292 | ||
| Predictive Performance of Physiologically Based Pharmacokinetic Models for the Effect of Food on Oral Drug Absorption: Current Status | Q49716638 | ||
| The impact of gastric pH, volume, and emptying on the food effect of ziprasidone oral absorption. | Q50786823 | ||
| Upper gastrointestinal (GI) pH in young, healthy men and women. | Q51615125 | ||
| Oral absorption of poorly water-soluble drugs: computer simulation of fraction absorbed in humans from a miniscale dissolution test. | Q52668360 | ||
| Development and validation of a preclinical food effect model | Q79318173 | ||
| PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: comparative assessement of prediction methods of human clearance | Q84032967 | ||
| P433 | issue | 1 | |
| P921 | main subject | pharmacokinetics | Q323936 |
| P304 | page(s) | 592-602 | |
| P577 | publication date | 2018-06-12 | |
| P1433 | published in | Journal of Pharmaceutical Sciences | Q3186933 |
| P1476 | title | Food Effect Projections via Physiologically Based Pharmacokinetic Modeling: Predictive Case Studies | |
| P478 | volume | 108 |
| Q89500030 | A multiscale absorption and transit model for oral drug delivery: Formulation and applications during fasting conditions |
| Q94538992 | Current State and Future Expectations of Translational Modeling Strategies to Support Drug Product Development, Manufacturing Changes and Controls: A Workshop Summary Report |
| Q102206232 | In vitro and in vivo evaluation of 3D printed capsules with pressure triggered release mechanism for oral peptide delivery |
| Q91510523 | Prediction of pH-Dependent Drug-Drug Interactions for Basic Drugs Using Physiologically Based Biopharmaceutics Modeling: Industry Case Studies |
| Q93006074 | Requirements to Establishing Confidence in Physiologically Based Pharmacokinetic (PBPK) Models and Overcoming Some of the Challenges to Meeting Them |
Search more.