Spinal cord degeneration in C57BL/6N mice following induction of experimental parkinsonism with MPTP.

scientific article published on 23 November 2007

Spinal cord degeneration in C57BL/6N mice following induction of experimental parkinsonism with MPTP. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1471-4159.2007.05091.X
P698PubMed publication ID18036149
P5875ResearchGate publication ID5811836

P2093author name stringNaren L Banik
Supriti Samantaray
Varduhi H Knaryan
Swapan K Ray
Jonathan T Butler
P2860cites workImmunofluorescent labeling of increased calpain expression and neuronal death in the spinal cord of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated miceQ44820160
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Neurotoxic effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the cat. Tyrosine hydroxylase immunohistochemistryQ48343791
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Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonismQ48614154
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Increased M-calpain expression in the mesencephalon of patients with Parkinson's disease but not in other neurodegenerative disorders involving the mesencephalon: a role in nerve cell death?Q48954833
The extraneuronal transporter for monoamine transmitters exists in cells derived from human central nervous system glia.Q55479576
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D-deprenyl protects nigrostriatal neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicityQ34215774
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Dopamine transporter: involvement in selective dopaminergic neurotoxicity and degenerationQ35916447
The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis ratsQ35925804
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A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridineQ37343442
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Calcium channel agonist, (±)-Bay K8644, causes a transient increase in striatal monoamine oxidase activity in Balb/c miceQ44427020
Calcium channel agonist, (+/-)-Bay K8644, causes an immediate increase in the striatal 1-methyl-4-phenylpyridinium level following systemic administration of the dopaminergic neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, in Balb/c miceQ44506297
Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.Q44746550
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectparkinsonian syndromeQ1531991
Parkinson's diseaseQ11085
P304page(s)1309-1320
P577publication date2007-11-23
P1433published inJournal of NeurochemistryQ6295643
P1476titleSpinal cord degeneration in C57BL/6N mice following induction of experimental parkinsonism with MPTP.
P478volume104

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cites work (P2860)
Q38295414Calpain inhibition protected spinal cord motoneurons against 1-methyl-4-phenylpyridinium ion and rotenone
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Q36021445Inhibition of Calpain Activation Protects MPTP-Induced Nigral and Spinal Cord Neurodegeneration, Reduces Inflammation, and Improves Gait Dynamics in Mice
Q43294352Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO).
Q48224687Reassessment of subacute MPTP-treated mice as animal model of Parkinson's disease
Q50067933Role of catalpol in ameliorating the pathogenesis of experimental autoimmune encephalomyelitis by increasing the level of noradrenaline in the locus coeruleus.
Q33686439SNJ-1945, a calpain inhibitor, protects SH-SY5Y cells against MPP(+) and rotenone
Q37851642Spinal cord and parkinsonism: Neuromorphological evidences in humans and experimental studies
Q48685237The vincamine derivative vindeburnol provides benefit in a mouse model of multiple sclerosis: effects on the Locus coeruleus
Q37880260Tracking extranigral degeneration in animal models of Parkinson’s disease: quest for effective therapeutic strategies

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