Decreased in vivo oxidative stress and decreased platelet activation following metformin treatment in newly diagnosed type 2 diabetic subjects

scientific article published in March 2008

Decreased in vivo oxidative stress and decreased platelet activation following metformin treatment in newly diagnosed type 2 diabetic subjects is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/DMRR.794
P698PubMed publication ID17966969

P2093author name stringAgostino Consoli
Assunta Pandolfi
Antonio Nicolucci
Elena A De Filippis
Giovanni Davì
Tonino Bucciarelli
Gloria Formoso
Giovanni Ciabattoni
Noemi Michetti
Patrizia Di Fulvio
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Platelet activation in type 2 diabetes mellitusQ28210554
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) GroupQ29547282
Clinical relevance of the oxidative stress concept.Q33849775
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Lipid peroxidation in diabetes mellitusQ34384380
Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetesQ34953482
Diabetes, oxidative stress, and antioxidants: a reviewQ35077717
Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptorsQ35603673
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Antidiabetic and antimalarial biguanide drugs are metal-interactive antiproteolytic agentsQ40569580
Antiplatelet agents in the prevention of diabetic vascular complications.Q40754772
In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation.Q42536696
Monotherapy with metformin: does it improve hypoxia in type 2 diabetic patients?Q43767224
An intracellular modulation of free radical production could contribute to the beneficial effects of metformin towards oxidative stressQ44449233
Lipid and protein oxidation contribute to a prothrombotic state in patients with type 2 diabetes mellitus.Q44518897
Diabetes mellitus, oxidative stress and advanced glycation endproductsQ44970615
Thromboxane biosynthesis and platelet function in type II diabetes mellitusQ45056796
Metformin prevents glucose-induced protein kinase C-beta2 activation in human umbilical vein endothelial cells through an antioxidant mechanismQ46406560
Assessing the predictive accuracy of QUICKI as a surrogate index for insulin sensitivity using a calibration modelQ46570511
In vivo formation of 8-Epi-prostaglandin F2 alpha is increased in hypercholesterolemia.Q50917467
Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease.Q50944772
Effect of metformin on glutathione and magnesium in normal and streptozotocin-induced diabetic rats.Q51585764
An insulin sensitizer improves the free radical defense system potential and insulin sensitivity in high fructose-fed rats.Q54095655
Radioimmunoassay of 11-dehydrothromboxane B2 in human plasma and urine.Q54137065
Effects of metformin on insulin resistance, risk factors for cardiovascular disease, and plasminogen activator inhibitor in NIDDM subjects. A study of two ethnic groups.Q54243732
Metformin reduces platelet hypersensitivity in hypercholesterolemic rabbitsQ57399014
The F2-isoprostane, 8-epi-prostaglandin F2 alpha, a potent agonist of the vascular thromboxane/endoperoxide receptor, is a platelet thromboxane/endoperoxide receptor antagonistQ67584372
Study of the effect of metformin on platelet aggregation in insulin-dependent diabeticsQ69579971
Increased production of platelet thromboxane B2 in non-insulin-dependent diabetes. Relationship to vascular complicationsQ70484534
Platelets from patients with diabetes mellitus have impaired ability to mediate vasodilationQ71071086
The mystery of diabetes and atherosclerosis: time for a new plotQ73070861
Effect of four-week metformin treatment on plasma and erythrocyte antioxidative defense enzymes in newly diagnosed obese patients with type 2 diabetesQ73557293
Effects of gliclazide versus metformin on the clinical profile and lipid peroxidation markers in type 2 diabetesQ78044125
Metformin reduces endothelial cell expression of both the receptor for advanced glycation end products and lectin-like oxidized receptor 1Q79756457
P433issue3
P921main subjectmetforminQ19484
P304page(s)231-237
P577publication date2008-03-01
P1433published inDiabetes - Metabolism: Research and ReviewsQ15750056
P1476titleDecreased in vivo oxidative stress and decreased platelet activation following metformin treatment in newly diagnosed type 2 diabetic subjects
P478volume24

Reverse relations

cites work (P2860)
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