Electric-Field-Induced Protein Translocation via a Conformational Transition in SecDF: An MD Study

scientific article published in June 2017

Electric-Field-Induced Protein Translocation via a Conformational Transition in SecDF: An MD Study is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BPJ.2017.04.034
P932PMC publication ID5479055
P698PubMed publication ID28636909

P2093author name stringIoan Andricioaei
Daun Jeong
Emel Ficici
P2860cites workAn Implicit Membrane Generalized Born Theory for the Study of Structure, Stability, and Interactions of Membrane ProteinsQ24537724
SecD and SecF are required for the proton electrochemical gradient stimulation of preprotein translocationQ24596484
CHARMM: the biomolecular simulation programQ24658108
The structural basis for the transition from Ras-GTP to Ras-GDPQ27639590
X-ray structure of a protein-conducting channelQ27642744
Structure of a complex of the ATPase SecA and the protein-translocation channelQ27652526
Conformational transition of Sec machinery inferred from bacterial SecYE structuresQ27652527
Structure and function of a membrane component SecDF that enhances protein exportQ27667802
The Sec translocaseQ27691857
A dynamic model for the allosteric mechanism of GroELQ28145239
ras genesQ29547799
Purification, crystallization and preliminary X-ray diffraction of SecDF, a translocon-associated membrane protein, from Thermus thermophilusQ33238385
The SecDFyajC domain of preprotein translocase controls preprotein movement by regulating SecA membrane cyclingQ33887254
The role of the alpha-helix dipole in protein function and structureQ34051011
The alpha-helix as an electric macro-dipoleQ34059840
Ion transport in a model gramicidin channel. Structure and thermodynamicsQ34127613
The unfolding action of GroEL on a protein substrateQ34186327
Archaeal and bacterial SecD and SecF homologs exhibit striking structural and functional conservation.Q34354021
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranesQ34719604
Single-Walled Carbon Nanotubes Modulate the B- to A-DNA TransitionQ34764440
Conformational variation of the translocon enhancing chaperone SecDF.Q35076035
On structural transitions, thermodynamic equilibrium, and the phase diagram of DNA and RNA duplexes under torque and tensionQ35133736
Analysis and Elimination of a Bias in Targeted Molecular Dynamics Simulations of Conformational Transitions: Application to CalmodulinQ36120569
Molecular switch in signal transduction: Reaction paths of the conformational changes in ras p21Q36626570
Proton transfer is rate-limiting for translocation of precursor proteins by the Escherichia coli translocaseQ37445539
SecD and SecF facilitate protein export in Escherichia coli.Q37628246
SecD is involved in the release of translocated secretory proteins from the cytoplasmic membrane of Escherichia coliQ38322783
Decrypting protein insertion through the translocon with free-energy calculationsQ38741855
Crystallization and preliminary X-ray diffraction of the first periplasmic domain of SecDF, a translocon-associated membrane protein, from Thermus thermophilusQ39013575
SecF stabilizes SecD and SecY, components of the protein translocation machinery of the Escherichia coli cytoplasmic membraneQ39932560
Computation of the dipole moments of proteinsQ41895763
Uncovering pH-dependent transient states of proteins with buried ionizable residuesQ42216392
Protein transport across the endoplasmic reticulum membraneQ42663824
The alpha-helix dipole and the properties of proteinsQ45281613
ΔμH+ and ATP function at different steps of the catalytic cycle of preprotein translocaseQ46481993
Structure of a transient intermediate for GTP hydrolysis by ras.Q46986468
SecDF of Bacillus subtilis, a molecular Siamese twin required for the efficient secretion of proteins.Q47724114
Generalized born model with a simple smoothing functionQ52009475
Calculation of pathways for the conformational transition between the GTP‐ and GDP‐bound states of the Ha‐ras‐p21 protein: Calculations with explicit solvent simulations and comparison with calculations in vacuumQ52261413
SecA promotes preprotein translocation by undergoing ATP-driven cycles of membrane insertion and deinsertionQ52513940
SecA membrane cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF.Q54598039
The proton motive force lowers the level of ATP required for the in vitro translocation of a secretory protein in Escherichia coli.Q54706217
Free Energy Landscape of A-DNA to B-DNA Conversion in Aqueous SolutionQ56770488
Targeted molecular dynamics: a new approach for searching pathways of conformational transitionsQ72696166
A dynamic analysis of the rotation mechanism for conformational change in F(1)-ATPaseQ74471754
Conformational pathway for the kissing complex-->extended dimer transition of the SL1 stem-loop from genomic HIV-1 RNA as monitored by targeted molecular dynamics techniquesQ80383214
P433issue12
P407language of work or nameEnglishQ1860
P1104number of pages9
P304page(s)2520-2528
P577publication date2017-06-01
P1433published inBiophysical JournalQ2032955
P1476titleElectric-Field-Induced Protein Translocation via a Conformational Transition in SecDF: An MD Study
P478volume112

Reverse relations

cites work (P2860)
Q47734450Driving Forces of Translocation Through Bacterial Translocon SecYEG.
Q64265916Effects of an Electric Field on the Conformational Transition of the Protein: A Molecular Dynamics Simulation Study
Q54201374The way is the goal: how SecA transports proteins across the cytoplasmic membrane in bacteria

Search more.