Addressing sufficiency of the CB1 receptor for endocannabinoid-mediated functions through conditional genetic rescue in forebrain GABAergic neurons

scientific article published on 9 April 2017

Addressing sufficiency of the CB1 receptor for endocannabinoid-mediated functions through conditional genetic rescue in forebrain GABAergic neurons is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S00429-017-1411-5
P932PMC publication ID5676814
P698PubMed publication ID28393261

P50authorFloor RemmersQ37829081
P2093author name stringHans-Christian Pape
Beat Lutz
Sabine Ruehle
Maren D Lange
Martina Hamann
P2860cites workCircuit specific functions of cannabinoid CB1 receptor in the balance of investigatory drive and explorationQ21134984
Endocannabinoid signaling in female reproductionQ24599033
Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneuronsQ28144567
CB1 cannabinoid receptors and on-demand defense against excitotoxicityQ28207143
Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signalingQ28253698
50 years of hurdles and hope in anxiolytic drug discoveryQ28297569
Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in miceQ28469322
Efficient in vivo manipulation of mouse genomic sequences at the zygote stageQ29547306
The endocannabinoid system controls food intake via olfactory processes.Q50861416
CB1 receptor stimulation in specific brain areas differently modulate anxiety-related behaviour.Q50891805
Cannabinoid CB1 receptor mediates fear extinction via habituation-like processes.Q50933420
[Endogenous cannabinoid system. Effect on neuronal plasticity and pain memory].Q51986613
Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain.Q52030475
Not too excited? Thank your endocannabinoidsQ80110872
Neuropeptide regulation of fear and anxiety: Implications of cholecystokinin, endogenous opioids, and neuropeptide Y.Q30453815
Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approachesQ30454438
The endocannabinoid system in anxiety, fear memory and habituationQ30471032
The accurate measurement of fear memory in Pavlovian conditioning: Resolving the baseline issueQ30474809
Presynaptic kainate receptor activation preserves asynchronous GABA release despite the reduction in synchronous release from hippocampal cholecystokinin interneuronsQ30496566
Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fearQ30497715
Short-term adaptation of conditioned fear responses through endocannabinoid signaling in the central amygdalaQ30498563
Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in miceQ30516052
GABAergic interneuron development and function is modulated by the Tsc1 geneQ30523993
Genetic rescue of CB1 receptors on medium spiny neurons prevents loss of excitatory striatal synapses but not motor impairment in HD miceQ30588621
Localization of the CB1 type cannabinoid receptor in the rat basolateral amygdala: high concentrations in a subpopulation of cholecystokinin-containing interneuronsQ31031335
AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicityQ33784846
Glutamic acid decarboxylase 65: a link between GABAergic synaptic plasticity in the lateral amygdala and conditioned fear generalizationQ33923646
Endogenous cannabinoids mediate retrograde signalling at hippocampal synapsesQ33940688
Multiple functions of endocannabinoid signaling in the brain.Q34270199
Neuronal circuits for fear and anxiety.Q34477053
A runner's high depends on cannabinoid receptors in miceQ34496926
Neuronal localization of cannabinoid receptors in the basal ganglia of the rat.Q34602111
GABA and Epilepsy: Their Complex Relationship and the Evolution of Our UnderstandingQ35226564
Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fearQ35612931
Subpopulations of somatostatin-immunoreactive non-pyramidal neurons in the amygdala and adjacent external capsule project to the basal forebrain: evidence for the existence of GABAergic projection neurons in the cortical nuclei and basolateral nucleQ36110456
Prenatal exposure to cannabinoids evokes long-lasting functional alterations by targeting CB1 receptors on developing cortical neuronsQ36268491
Biphasic effects of cannabinoids in anxiety responses: CB1 and GABA(B) receptors in the balance of GABAergic and glutamatergic neurotransmission.Q36323518
Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies.Q36612284
Alterations in the hippocampal endocannabinoid system in diet-induced obese mice.Q36795697
The basolateral amygdala γ-aminobutyric acidergic system in health and diseaseQ36813950
Multiple roles for the endocannabinoid system during the earliest stages of life: pre- and postnatal developmentQ37143586
Fear extinction causes target-specific remodeling of perisomatic inhibitory synapsesQ37341518
Endocannabinoid-mediated control of synaptic transmissionQ37363621
Prefrontal cortical circuit for depression- and anxiety-related behaviors mediated by cholecystokinin: role of ΔFosB.Q37633608
Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stressQ37925172
Fear relief-toward a new conceptual frame work and what endocannabinoids gotta do with it.Q37968824
Kainate receptors in the hippocampusQ38205016
Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapsesQ38280778
Weeding out bad waves: towards selective cannabinoid circuit control in epilepsyQ38428721
A highly conserved enhancer in the Dlx5/Dlx6 intergenic region is the site of cross-regulatory interactions between Dlx genes in the embryonic forebrain.Q38460077
Functional neuroanatomy of amygdalohippocampal interconnections and their role in learning and memoryQ38733532
2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons.Q39191943
Activation of the cannabinoid receptor type 1 decreases glutamatergic and GABAergic synaptic transmission in the lateral amygdala of the mouseQ39897578
Identification and Characterization of GABAergic Projection Neurons from Ventral Hippocampus to AmygdalaQ41612450
The endocannabinoid system controls key epileptogenic circuits in the hippocampusQ42065383
Differential Control of Cocaine Self-Administration by GABAergic and Glutamatergic CB1 Cannabinoid ReceptorsQ42124542
State-dependent, bidirectional modulation of neural network activity by endocannabinoids.Q42497466
A kainate receptor increases the efficacy of GABAergic synapsesQ42505488
Distribution of CB1 cannabinoid receptors in the amygdala and their role in the control of GABAergic transmission.Q42513159
Activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the lateral amygdalaQ42525505
Endocannabinoids render exploratory behaviour largely independent of the test aversiveness: role of glutamatergic transmissionQ42626129
Bimodal control of stimulated food intake by the endocannabinoid system.Q43169799
Synaptic activation of kainate receptors gates presynaptic CB(1) signaling at GABAergic synapsesQ43191478
Calbindin D28k-containing nonpyramidal cells in the rat hippocampus: Their immunoreactivity for GABA and projection to the medial septumQ43523135
Presynaptic cannabinoid sensitivity is a major determinant of depolarization-induced retrograde suppression at hippocampal synapses.Q43999138
The endogenous cannabinoid system controls extinction of aversive memoriesQ44085607
Neuron-type specific cannabinoid-mediated G protein signalling in mouse hippocampusQ44195848
Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdalaQ44998040
Analysis in conditional cannabinoid 1 receptor-knockout mice reveals neuronal subpopulation-specific effects on epileptogenesis in the kindling paradigmQ45307175
Behavioral and cortical EEG evaluations confirm the roles of both CCKA and CCKB receptors in mouse CCK-induced anxietyQ45741110
Endocannabinoids mediate acute fear adaptation via glutamatergic neurons independently of corticotropin-releasing hormone signalingQ46200896
Presynaptic, activity-dependent modulation of cannabinoid type 1 receptor-mediated inhibition of GABA release.Q46366644
Synaptology of ventral CA1 and subiculum projections to the basomedial nucleus of the amygdala in the mouse: relation to GABAergic interneuronsQ46627176
Role in anxiety behavior of the endocannabinoid system in the prefrontal cortexQ46962183
The endocannabinoid system in guarding against fear, anxiety and stressQ47618301
Bimodal control of fear-coping strategies by CB₁ cannabinoid receptors.Q47720196
Dissociation between the panicolytic effect of cannabidiol microinjected into the substantia nigra, pars reticulata, and fear-induced antinociception elicited by bicuculline administration in deep layers of the superior colliculus: The role of CB1-cQ47721559
Context-dependent effects of CB1 cannabinoid gene disruption on anxiety-like and social behaviour in mice.Q47781181
Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression.Q47954570
Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons: distinctive sufficiency for hippocampus-dependent and amygdala-dependent synaptic and behavioral functions.Q48007584
Ventral tegmental area cannabinoid type-1 receptors control voluntary exercise performanceQ48255216
Cannabinoid CB1 receptors in distinct circuits of the extended amygdala determine fear responsiveness to unpredictable threatQ48489059
Anatomical characterization of the cannabinoid CB1 receptor in cell-type-specific mutant mouse rescue modelsQ48658572
Pharmacological activation of kainate receptors drives endocannabinoid mobilizationQ48899592
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P921main subjectendocannabinoidsQ10483908
P304page(s)3431-3452
P577publication date2017-04-09
P1433published inBrain Structure and FunctionQ13444883
P1476titleAddressing sufficiency of the CB1 receptor for endocannabinoid-mediated functions through conditional genetic rescue in forebrain GABAergic neurons
P478volume222

Reverse relations

cites work (P2860)
Q47234867Cannabinoid receptor 1/2 double-knockout mice develop epilepsy
Q94569525Endocannabinoid System Components as Potential Biomarkers in Psychiatry
Q50200300Functional relevance of endocannabinoid-dependent synaptic plasticity in the CNS.
Q52730389Localization of the cannabinoid type-1 receptor in subcellular astrocyte compartments of mutant mouse hippocampus.
Q60949363Proteomic Profile of Carbonylated Proteins Screen Regulation of Apoptosis via CaMK Signaling in Response to Regular Aerobic Exercise
Q64122226The motivation for exercise over palatable food is dictated by cannabinoid type-1 receptors

Search more.