Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority tria

scientific article published on 4 December 2015

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority tria is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0140-6736(15)01041-7
P932PMC publication ID5724392
P698PubMed publication ID26670617

P50authorPeng WeiQ47100630
Theodosia A. KalfaQ47100638
Russell E WareQ56785312
Barry R. DavisQ64684716
Janet L KwiatkowskiQ89645734
P2093author name stringJohn Wood
William Owen
Abdullah Kutlar
Robert J Adams
Kathleen J Helton
Alan R Cohen
Naomi L C Luban
Margaret T Lee
Lori Luchtman-Jones
Judy Luden
R Clark Brown
Scott T Miller
Zora R Rogers
Sara Pressel
Stephen Nelson
Matthew M Heeney
Alexis A Thompson
Banu Aygun
Beng Fuh
Ofelia Alvarez
Alex George
Nicole A Mortier
William H Schultz
Isaac Odame
Melissa Rhodes
Hamayun Imran
Sharada Sarnaik
Jennifer A Rothman
Melanie J Bonner
Cynthia Gauger
Connie Piccone
Niren Patel
Lee Hilliard
Donna Roberts
Linda Piller
Kerri Nottage
Jamie Coleman
Sherron Jackson
Carla Roberts
Susan E Stuber
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Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell diseaseQ34557931
Genetic predictors for stroke in children with sickle cell anemiaQ35067635
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Stroke With Transfusions Changing to Hydroxyurea (SWiTCH): a phase III randomized clinical trial for treatment of children with sickle cell anemia, stroke, and iron overloadQ35209572
Effect of transfusion therapy on transcranial Doppler ultrasonography velocities in children with sickle cell diseaseQ36011461
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Hydroxyurea therapy lowers transcranial Doppler flow velocities in children with sickle cell anemiaQ36788867
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Prevention of secondary stroke and resolution of transfusional iron overload in children with sickle cell anemia using hydroxyurea and phlebotomyQ45041402
Hydroxyurea for sickle cell disease in children and for prevention of cerebrovascular events: the Belgian experience.Q45190220
Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonographyQ47906551
Chronic transfusion practices for prevention of primary stroke in children with sickle cell anemia and abnormal TCD velocities.Q53391834
The use of transcranial ultrasonography to predict stroke in sickle cell disease.Q55043495
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P433issue10019
P407language of work or nameEnglishQ1860
P921main subjecttranscranial DopplerQ3512319
hydroxycarbamideQ212272
P1104number of pages10
P304page(s)661-670
P577publication date2015-12-04
P1433published inThe LancetQ939416
P1476titleHydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority tria
P478volume387

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