scholarly article | Q13442814 |
P50 | author | Sandra D Mulder | Q82597817 |
Sandra Villegas | Q37370937 | ||
P2093 | author name string | Robert Veerhuis | |
Laia Montoliu-Gaya | |||
P2860 | cites work | Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro | Q24321663 |
ApoE promotes the proteolytic degradation of Abeta | Q24651102 | ||
Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons | Q27301082 | ||
Astrocytes: biology and pathology | Q27490746 | ||
Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions | Q27672294 | ||
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families | Q27860677 | ||
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics | Q27860914 | ||
Apolipoprotein E: far more than a lipid transport protein | Q28204471 | ||
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy | Q28282855 | ||
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease | Q28504767 | ||
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease | Q29614881 | ||
Decreased clearance of CNS beta-amyloid in Alzheimer's disease | Q29616534 | ||
Alzheimer's disease | Q29616743 | ||
Two adjacent domains (141-150 and 151-160) of apoE covalently linked to a class A amphipathic helical peptide exhibit opposite atherogenic effects. | Q30497594 | ||
Binding and uptake of A beta1-42 by primary human astrocytes in vitro | Q33390631 | ||
Anti-inflammatory and recycling properties of an apolipoprotein mimetic peptide, Ac-hE18A-NH(2) | Q33618352 | ||
In vivo and in vitro effects of an apolipoprotein e mimetic peptide on amyloid-β pathology | Q33995580 | ||
Methods for analysis of amyloid-β aggregates. | Q34095967 | ||
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease | Q34157492 | ||
Structure and lipid interactions of an anti-inflammatory and anti-atherogenic 10-residue class G⁎ apolipoprotein J peptide using solution NMR | Q34384359 | ||
The pathogenesis of senile plaques | Q34421483 | ||
Apolipoprotein E: From lipid transport to neurobiology | Q34497951 | ||
Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system | Q34559847 | ||
Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease | Q34960461 | ||
Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity | Q35608051 | ||
Combined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 Mice | Q36065117 | ||
Extracellular chaperones prevent Aβ42-induced toxicity in rat brains. | Q50747899 | ||
Apolipoprotein E and antioxidants have different mechanisms of inhibiting Alzheimer's beta-amyloid fibril formation in vitro. | Q52226054 | ||
SP-40,40 is a constituent of Alzheimer's amyloid | Q53179261 | ||
Competition of Abeta amyloid peptide and apolipoprotein E for receptor-mediated endocytosis. | Q53226591 | ||
Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins | Q68921833 | ||
An ApoE-Abeta inhibition complex in Abeta fibril extension | Q71824491 | ||
Amyloid associated proteins in Alzheimer's and prion disease | Q36173056 | ||
Apolipoprotein E, amyloid-ß clearance and therapeutic opportunities in Alzheimer's disease | Q36424857 | ||
Mechanisms of Disease: astrocytes in neurodegenerative disease | Q36658874 | ||
ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions | Q36835522 | ||
The effect of apolipoprotein mimetic peptides in inflammatory disorders other than atherosclerosis | Q37097367 | ||
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease | Q37118356 | ||
Biochemistry and molecular biology of amyloid beta-protein and the mechanism of Alzheimer's disease | Q37217951 | ||
Loss of deep cerebellar nuclei neurons in the 3xTg-AD mice and protection by an anti-amyloid β antibody fragment | Q37364347 | ||
Early intervention in the 3xTg-AD mice with an amyloid β-antibody fragment ameliorates first hallmarks of Alzheimer disease. | Q37364350 | ||
The amyloid hypothesis for Alzheimer's disease: a critical reappraisal | Q37490185 | ||
Apolipoprotein E mimetics and cholesterol-lowering properties | Q37965590 | ||
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes | Q37979641 | ||
Inflammation in Alzheimer's Disease and Molecular Genetics: Recent Update | Q38558744 | ||
Complex and differential glial responses in Alzheimer's disease and ageing | Q38753519 | ||
Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role. | Q38904336 | ||
Ammonium hydroxide treatment of Aβ produces an aggregate free solution suitable for biophysical and cell culture characterization | Q39418248 | ||
Clusterin overexpression and its possible protective role in transthyretin deposition in familial amyloidotic polyneuropathy | Q39443274 | ||
An anti-Aβ (amyloid β) single-chain variable fragment prevents amyloid fibril formation and cytotoxicity by withdrawing Aβ oligomers from the amyloid pathway | Q39557102 | ||
Functional and structural properties of lipid-associated apolipoprotein J (clusterin). | Q41815057 | ||
The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex | Q42161240 | ||
Elongation of the C-terminal domain of an anti-amyloid β single-chain variable fragment increases its thermodynamic stability and decreases its aggregation tendency | Q42846245 | ||
Astrocytic A beta 1-42 uptake is determined by A beta-aggregation state and the presence of amyloid-associated proteins | Q43026196 | ||
Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy. | Q44132564 | ||
An oral apoJ peptide renders HDL antiinflammatory in mice and monkeys and dramatically reduces atherosclerosis in apolipoprotein E-null mice. | Q46119869 | ||
Seeding of A beta fibril formation is inhibited by all three isotypes of apolipoprotein E. | Q46722154 | ||
Understanding the contribution of disulfide bridges to the folding and misfolding of an anti-Aβ scFv | Q48364112 | ||
Microglia show altered morphology and reduced arborization in human brain during aging and Alzheimer's disease. | Q48424552 | ||
The role of astrocytes in amyloid β-protein toxicity and clearance | Q48520121 | ||
Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab | Q48852013 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | e0188191 | |
P577 | publication date | 2017-11-20 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Effects of an Aβ-antibody fragment on Aβ aggregation and astrocytic uptake are modulated by apolipoprotein E and J mimetic peptides | |
P478 | volume | 12 |
Q99414188 | Both Amyloid-β Peptide and Tau Protein Are Affected by an Anti-Amyloid-β Antibody Fragment in Elderly 3xTg-AD Mice | cites work | P2860 |
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