Ticking time bombs: connections between circadian clocks and cancer.

scientific article published on 30 October 2017

Ticking time bombs: connections between circadian clocks and cancer. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.12688/F1000RESEARCH.11770.1
P932PMC publication ID5664980
P698PubMed publication ID29152229

P50authorKatja A LamiaQ88621221
P2093author name stringKatja A Lamia
P2860cites workNight shift work, chronotype and prostate cancer risk in the MCC-Spain case-control study.Q53656340
Total mortality and cause-specific mortality of Swedish shift- and dayworkers in the pulp and paper industry in 1952-2001Q57224688
On circadian rhythms in human epidermal cell proliferationQ68305471
The diurnal variations in the tissue glycogen content and their relation to mitotic activity in the adult male mouseQ75648029
Continuous light or darkness and circadian periodic mitosis and metabolism in C and D8 miceQ78865859
Shift workers' mortality scrutinizedQ81260733
RE: Night Shift Work and Breast Cancer Incidence: Three Prospective Studies and Meta-analysis of Published StudiesQ87750854
RE: Night Shift Work and Breast Cancer Incidence: Three Prospective Studies and Meta-analysis of Published StudiesQ95513712
Hallmarks of Cancer: The Next GenerationQ22252312
Clock Mutants of Drosophila melanogasterQ22337192
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilizationQ24292930
Purification and properties of human blue-light photoreceptor cryptochrome 2Q24297358
Coupling of human circadian and cell cycles by the timeless proteinQ24299164
Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2Q24303581
SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteinsQ24304073
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligaseQ24304122
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signalingQ24306275
Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clockQ24318706
Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic LesionsQ24563025
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetesQ24633002
Targeting the PI3K signaling pathway in cancerQ24647554
A genome-wide RNAi screen for modifiers of the circadian clock in human cellsQ24655808
Molecular architecture of the mammalian circadian clockQ27004052
Timeless Interacts with PARP-1 to Promote Homologous Recombination RepairQ27702096
Associations among rotating night shift work, sleep and skin cancer in Nurses' Health Study II participantsQ27908579
The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivoQ28206180
A dynamic role of HAUSP in the p53-Mdm2 pathwayQ28253645
Tumour suppression: disruption of HAUSP gene stabilizes p53Q28254102
The circadian clock component BMAL1 is a critical regulator of p21WAF1/CIP1 expression and hepatocyte proliferationQ28261349
ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activationQ28265951
Occupational exposure and risk of breast cancerQ28388591
Case-control study of shift-work and breast cancer risk in Danish nurses: impact of shift systems.Q50554473
Nested case-control study of night shift work and breast cancer risk among women in the Danish military.Q50556511
Reciprocal Regulation between the Circadian Clock and Hypoxia Signaling at the Genome Level in Mammals.Q51367975
Circadian Clock Interaction with HIF1α Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle.Q51367982
The circadian molecular clock creates epidermal stem cell heterogeneity.Q51847597
Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expressionQ28509189
Requirement of Mammalian Timeless for Circadian RhythmicityQ28566744
Circadian clock protein BMAL1 regulates cellular senescence in vivoQ28588741
Phosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period lengthQ28590815
The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian periodQ28594339
Model-driven experimental approach reveals the complex regulatory distribution of p53 by the circadian factor Period 2Q28818349
Night Shift Work and Breast Cancer Incidence: Three Prospective Studies and Meta-analysis of Published StudiesQ29248161
Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clockQ29616363
The genetics of mammalian circadian order and disorder: implications for physiology and diseaseQ29616366
Physiological significance of a peripheral tissue circadian clockQ29619075
Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cellsQ29619080
Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle.Q30584251
Enhancing circadian clock function in cancer cells inhibits tumor growthQ30838731
Circadian oscillation of nucleotide excision repair in mammalian brainQ33402391
Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stressQ33541382
Systems ChronotherapeuticsQ33573675
Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in miceQ33601559
Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint controlQ33661490
Ras-mediated deregulation of the circadian clock in cancerQ33685542
Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complexQ33783874
Circadian rhythms and the circadian organization of living systemsQ34248582
Entrainment of the mammalian cell cycle by the circadian clock: modeling two coupled cellular rhythmsQ34302123
NONO couples the circadian clock to the cell cycleQ34319589
Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatmentQ34385041
The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cellsQ34504101
The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cellsQ34522359
JETLAG resets the Drosophila circadian clock by promoting light-induced degradation of TIMELESS.Q34541185
Rhythmic Oxygen Levels Reset Circadian Clocks through HIF1α.Q34543299
CRY2 and FBXL3 Cooperatively Degrade c-MYC.Q34544579
Association of the circadian factor Period 2 to p53 influences p53's function in DNA-damage signalingQ34960791
Robust synchronization of coupled circadian and cell cycle oscillators in single mammalian cellsQ34986577
The hepatic circadian clock modulates xenobiotic metabolism in miceQ35138004
DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilizationQ35156678
The core circadian gene Cryptochrome 2 influences breast cancer risk, possibly by mediating hormone signalingQ35220012
The circadian mutation PER2(S662G) is linked to cell cycle progression and tumorigenesisQ35754678
Chronic shift-lag alters the circadian clock of NK cells and promotes lung cancer growth in ratsQ35803377
Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermisQ36122673
MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.Q36760018
Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cyclingQ36915650
Loss of cryptochrome reduces cancer risk in p53 mutant miceQ37081282
SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeedingQ37099495
Structure and function of animal cryptochromes.Q37140984
Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complexQ37289330
Circadian Kinetics of Cell Cycle Progression in Adult Neurogenic Niches of a Diurnal Vertebrate.Q37658135
The circadian timing system in clinical oncologyQ38219193
Carcinogenicity of shift-work, painting, and fire-fightingQ38459347
The Liver Circadian Clock Modulates Biochemical and Physiological Responses to MetforminQ38620481
Dosing-Time Makes the Poison: Circadian Regulation and PharmacotherapyQ38804914
Circadian gene variants and breast cancer.Q39007686
Effects of the biological clock gene Bmal1 on tumour growth and anti-cancer drug activityQ39688575
RE: Night Shift Work and Breast Cancer Incidence: Three Prospective Studies and Meta-analysis of Published Studies.Q40258746
Chronically Alternating Light Cycles Increase Breast Cancer Risk in Mice.Q40713268
Circadian synchronization of liver regeneration in adult rats: the role played by adrenal hormones.Q41286017
An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in miceQ41300170
Circadian Rhythm Disruption Promotes Lung TumorigenesisQ41921459
Clock gene Per2 as a controller of liver carcinogenesisQ42003261
Lung Adenocarcinoma Distally Rewires Hepatic Circadian HomeostasisQ42293291
Host circadian clock as a control point in tumor progression.Q43976271
Circadian rhythm of cellular proliferation in the human rectal mucosaQ43999604
Dispersed cell suspensions of fetal SCN restore circadian rhythmicity in SCN-lesioned adult hamsters.Q45018324
Effects of chronic jet lag on tumor progression in mice.Q45134031
Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity.Q46677190
Circadian Homeostasis of Liver Metabolism Suppresses HepatocarcinogenesisQ47110918
A multiscale modelling approach for the regulation of the cell cycle by the circadian clock.Q47827362
Critical cholangiocarcinogenesis control by cryptochrome clock genesQ48209599
Control mechanism of the circadian clock for timing of cell division in vivoQ48219610
Rotating Night-Shift Work and the Risk of Breast Cancer in the Nurses' Health StudiesQ48644965
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectcircadian rhythmQ208353
P304page(s)1910
P577publication date2017-10-30
P1433published inF1000ResearchQ27701587
P1476titleTicking time bombs: connections between circadian clocks and cancer
P478volume6

Reverse relations

cites work (P2860)
Q56958430A Systems-Level Analysis Reveals Circadian Regulation of Splicing in Colorectal Cancer
Q92296286A bioinformatic analysis identifies circadian expression of splicing factors and time-dependent alternative splicing events in the HD-MY-Z cell line
Q95661173A tail of CRY selectivity
Q57026779CLOCK and BMAL1 stabilize and activate RHOA to promote F-actin formation in cancer cells
Q61811447Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth
Q54959553Clinical chronobiology: a timely consideration in critical care medicine.
Q49396002Evidence for widespread dysregulation of circadian clock progression in human cancer
Q64080120G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment
Q64904590It’s About Time: Advances in Understanding the Circadian Regulation of DNA Damage and Repair in Carcinogenesis and Cancer Treatment Outcomes.
Q91452385Molecular mechanisms and physiological importance of circadian rhythms
Q57162844Programmed environmental illumination during autologous stem cell transplantation hospitalization for the treatment of multiple myeloma reduces severity of depression: A preliminary randomized controlled trial
Q89861104Shift Work and Prostate Cancer: An Updated Systematic Review and Meta-Analysis
Q64064088Telling the Time with a Broken Clock: Quantifying Circadian Disruption in Animal Models
Q52727400The Genomic Landscape and Pharmacogenomic Interactions of Clock Genes in Cancer Chronotherapy.
Q94450962Vital-sign circadian rhythms in patients prior to discharge from an ICU: a retrospective observational analysis of routinely recorded physiological data

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