Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth.

scientific article published on 23 November 2017

Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.31181
P932PMC publication ID5736349
P698PubMed publication ID29168692

P50authorHuda ZoghbiQ1633764
Akash J PatelQ47133369
Anna VainshteinQ47133378
Tiemo J KlischQ88838777
P2093author name stringTiemo J Klisch
P2860cites workIdentification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cellsQ24306666
Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesisQ24314479
JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatinQ24318979
Janus kinases in immune cell signalingQ24322021
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Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivoQ28368373
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Vertebrate non-receptor protein-tyrosine kinase familiesQ34425007
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Medullospheres from DAOY, UW228 and ONS-76 cells: increased stem cell population and proteomic modificationsQ34744495
PI3K inhibitors for cancer treatment: where do we stand?Q34921551
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Role of JAK2 in the pathogenesis and therapy of myeloproliferative disordersQ36919975
TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau.Q37407659
Integrated Proteomic and Transcriptomic-Based Approaches to Identifying Signature Biomarkers and Pathways for Elucidation of Daoy and UW228 SubtypesQ37728564
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An Anatomically Resolved Mouse Brain Proteome Reveals Parkinson Disease-relevant Pathways.Q38762606
AG490, a Jak2 inhibitor, suppressed the progression of murine ovarian cancerQ38832123
Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating GlioblastomaQ39778880
Deletion of Atoh1 disrupts Sonic Hedgehog signaling in the developing cerebellum and prevents medulloblastomaQ40172921
Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastomaQ41980889
Cerebellar granule cell neurogenesis is regulated by cell-cell interactions in vitroQ48725497
Functional conservation of atonal and Math1 in the CNS and PNS.Q52171174
HaloTag-based purification of functional human kinases from mammalian cells.Q53285553
The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread.Q53492300
Bimolecular-fluorescence complementation assay to monitor kinase-substrate interactions in vivo.Q54568154
MedulloblastomaQ84749666
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P921main subjectmedulloblastomaQ1333608
P577publication date2017-11-23
P1433published ineLifeQ2000008
P1476titleJak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth
P478volume6