Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study

scientific article published on 6 December 2017

Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1099691936
P356DOI10.1186/S13058-017-0920-8
P932PMC publication ID5719923
P698PubMed publication ID29212525

P50authorRichard WeinshilboumQ52447985
Krishna R KalariQ57034862
Kevin J ThompsonQ59692281
Zhenkun LouQ87718627
Liewei WangQ89121645
James N IngleQ89668737
Ann M MoyerQ90669273
Judy BougheyQ92381506
Matthew P GoetzQ95259846
Alvaro Moreno-AspitiaQ96172888
Vera J SumanQ96186734
Jason P SinnwellQ100957801
Daniel W VisscherQ108126317
Donald W NorthfeltQ116795045
Amy L ConnersQ116795054
P2093author name stringYan Lu
Katherine Minter-Dykhouse
Bo Qin
Ping Yin
Jia Yu
John A Copland
Xiaojia Tang
Richard J Gray
Laura A Marlow
Anthony Schweitzer
Bowen Gao
Sarah A McLaughlin
James L Miller
Jason Hubbard
Katie Hunt
P2860cites workA transmembrane intracellular estrogen receptor mediates rapid cell signalingQ24294726
Patient-derived tumour xenografts as models for oncology drug developmentQ24604068
Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomesQ24630783
Comprehensive molecular portraits of human breast tumoursQ24630844
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypesQ24647928
Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) miceQ24669724
Patient-derived xenograft models of breast cancer and their predictive powerQ27026531
A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancerQ27851787
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implicationsQ27860709
Molecular portraits of human breast tumoursQ28032461
Genome remodelling in a basal-like breast cancer metastasis and xenograftQ28395637
APE: Analyses of Phylogenetics and Evolution in R languageQ29546513
Cancer drug resistance: an evolving paradigmQ29616694
American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancerQ30494798
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristicsQ33330850
Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast CancerQ33614238
Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibitionQ33739184
Establishment and genomic characterization of mouse xenografts of human primary prostate tumorsQ33745240
Transgenic mouse models of human breast cancerQ34130558
Patient-derived xenograft models: an emerging platform for translational cancer researchQ34205518
Modelling breast cancer: one size does not fit all.Q34667643
Overview of resistance to systemic therapy in patients with breast cancerQ34712197
Strategies for subtypes--dealing with the diversity of breast cancer: highlights of the St. Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011Q35130819
Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistanceQ35558646
Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trialsQ35740423
Growth characteristics and metastatic properties of human breast cancer xenografts in immunodeficient miceQ35765489
Exome sequencing reveals frequent deleterious germline variants in cancer susceptibility genes in women with invasive breast cancer undergoing neoadjuvant chemotherapyQ36025853
Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.Q36047387
Patient-derived models of human breast cancer: protocols for in vitro and in vivo applications in tumor biology and translational medicineQ36778929
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.Q36892577
Patient-derived breast tumor xenografts facilitating personalized cancer therapyQ36903447
A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft modelsQ37067545
Critical choices for modeling breast cancer in transgenic mouse models.Q37968500
Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysisQ38188183
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.Q38826826
Interrogating open issues in cancer precision medicine with patient-derived xenografts.Q39095733
A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.Q39751877
A new model of patient tumor-derived breast cancer xenografts for preclinical assaysQ40112517
Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapseQ41135046
Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline updateQ57130157
The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in MiceQ62963901
Locally advanced breast cancer: comparison of mammography, sonography and MR imaging in evaluation of residual disease in women receiving neoadjuvant chemotherapyQ76383821
An in vivo platform for translational drug development in pancreatic cancerQ80087890
Modeling of response to endocrine therapy in a panel of human luminal breast cancer xenograftsQ82044929
Preclinical xenograft models of human sarcoma show nonrandom loss of aberrationsQ84466734
P433issue1
P921main subjectchemotherapyQ974135
xenograftQ64148587
P304page(s)130
P577publication date2017-12-06
P1433published inBreast Cancer ResearchQ2208481
P1476titleEstablishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study
P478volume19

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cites work (P2860)
Q64389037ATR Inhibition Is a Promising Radiosensitizing Strategy for Triple-Negative Breast Cancer
Q92757507Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations
Q88511739DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine
Q52720231Discovery of a glucocorticoid receptor (GR) activity signature using selective GR antagonism in ER-negative breast cancer.
Q92133167Drug responses are conserved across patient-derived xenograft models of melanoma leading to identification of novel drug combination therapies
Q64108509Factors that influence response classifications in chemotherapy treated patient-derived xenografts (PDX)
Q64957213Integrative In Vivo Drug Testing Using Gene Expression Signature and Patient-Derived Xenografts from Treatment-Refractory HER2 Positive and Triple-Negative Subtypes of Breast Cancer.
Q99721505Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
Q92941564Patient-Derived Xenograft Models of Breast Cancer and Their Application
Q64107259Post-neoadjuvant treatment and the management of residual disease in breast cancer: state of the art and perspectives
Q92971607Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall
Q64906876Systematic Review of Patient-Derived Xenograft Models for Preclinical Studies of Anti-Cancer Drugs in Solid Tumors.
Q61443907The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer