Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

scientific article published on 8 November 2011

Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2011PNAS..10818708G
P356DOI10.1073/PNAS.1111840108
P932PMC publication ID3219108
P698PubMed publication ID22068913
P5875ResearchGate publication ID51784713

P50authorMichael M. GottesmanQ6832389
Sudhir VarmaQ42564591
Anna M. CalcagnoQ42718489
Anil K. SoodQ88114757
P2093author name stringMiguel Marino
Bo R Rueda
Jean-Pierre Gillet
Suresh V Ambudkar
Ben Davidson
Ram Ganapathi
Josiah N Orina
Chirayu Patel
Vineet Singal
Lisa J Green
Raji Padmanabhan
Tatiana A Eliseeva
Meena I Vora
P2860cites workCharacterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.Q42445479
Increased platinum-DNA damage tolerance is associated with cisplatin resistance and cross-resistance to various chemotherapeutic agents in unrelated human ovarian cancer cell linesQ42814149
Cross-resistance to methotrexate and metals in human cisplatin-resistant cell lines results from a pleiotropic defect in accumulation of these compounds associated with reduced plasma membrane binding proteins.Q42816887
BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacyQ43606278
Mislocalization of membrane proteins associated with multidrug resistance in cisplatin-resistant cancer cell linesQ44605132
Apoptotic pathways of epothilone BMS 310705Q44608420
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How accurate are cancer cell lines?Q59088382
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Distinct types of diffuse large B-cell lymphoma identified by gene expression profilingQ27860529
The NCI60 human tumour cell line anticancer drug screenQ29614975
Targeting multidrug resistance in cancerQ29616803
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapyQ29617584
A gene expression database for the molecular pharmacology of cancerQ29619242
ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemiaQ33251273
The biology of ovarian cancer: new opportunities for translationQ33622369
Systematic evaluation of three microRNA profiling platforms: microarray, beads array, and quantitative real-time PCR arrayQ33828375
Chemosensitivity prediction by transcriptional profilingQ33943845
Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristicsQ34267466
A global map of human gene expressionQ34280845
Clinical relevance of multidrug resistance gene expression in ovarian serous carcinoma effusions.Q35575176
Molecular concepts analysis links tumors, pathways, mechanisms, and drugsQ35812701
Models of ovarian cancer--are we there yet?Q36162833
DualChip microarray as a new tool in cancer researchQ36481097
Microarray analysis and tumor classificationQ36499716
Establishment of an immortalised human ovarian surface epithelial cell line without chromosomal instabilityQ36614811
Chemotherapy-induced resistance by ATP-binding cassette transporter genes.Q36850578
Lost in translation: problems and pitfalls in translating laboratory observations to clinical utilityQ37106813
Gene-expression profiling in epithelial ovarian cancerQ37224303
A complex barcode underlies the heterogeneous response of p53 to stressQ37249372
Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery databaseQ37330648
Cytoplasmic functions of the tumour suppressor p53.Q37466228
Animal models of ovarian cancerQ37599439
Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agentsQ37714306
Molecular characterization of ovarian cancer by gene-expression profiling.Q37741508
Transcriptional regulation by p53.Q37777267
Do predictive signatures really predict response to cancer chemotherapy?Q37819795
Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestrationQ38291182
Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genesQ38333027
Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cellsQ38337454
ABC transporter A3 facilitates lysosomal sequestration of imatinib and modulates susceptibility of chronic myeloid leukemia cell lines to this drugQ39780753
P433issue46
P407language of work or nameEnglishQ1860
P304page(s)18708-18713
P577publication date2011-11-08
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleRedefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance
P478volume108

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