In Vivo Attenuation of Antibody-Mediated Acute Renal Allograft Rejection by Ex Vivo TGF-β-Induced CD4+Foxp3+ Regulatory T Cells

scientific article published on 16 October 2017

In Vivo Attenuation of Antibody-Mediated Acute Renal Allograft Rejection by Ex Vivo TGF-β-Induced CD4+Foxp3+ Regulatory T Cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2017.01334
P932PMC publication ID5650643
P698PubMed publication ID29085374

P50authorDavid D BrandQ56999832
P2093author name stringMingyu Liu
Siwen Li
Song Guo Zheng
Qiquan Sun
Jingrong Chen
Tao Liao
Yannan Zhang
Daqiang Zhao
Youqiu Xue
Haofeng Zheng
P2860cites workNatural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.Q47726082
Plasma-cell-rich infiltrates in paediatric renal transplant biopsies are associated with increased risk of renal allograft failureQ48271416
Endothelial injury in transplant glomerulopathy is correlated with transcription factor T-bet expression.Q50582511
Sequential analysis of donor-specific antibodies and pathological findings in acute antibody-mediated rejection in a rat renal transplantation modelQ51043732
NK cell transcripts and NK cells in kidney biopsies from patients with donor-specific antibodies: evidence for NK cell involvement in antibody-mediated rejection.Q51676450
Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation.Q51770870
Transfer of regulatory T cells generated ex vivo modifies graft rejection through induction of tolerogenic CD4+CD25+ cells in the recipient.Q53640510
Association of CD20+ infiltrates with poorer clinical outcomes in acute cellular rejection of renal allografts.Q53662129
Plasmapheresis followed by intravenous immunoglobulin in presensitized patients awaiting thoracic organ transplantationQ77392824
The requirement for granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in leukocyte-mediated immune glomerular injuryQ77531546
The cellular lesion of humoral rejection: predominant recruitment of monocytes to peritubular and glomerular capillariesQ79731732
Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-betaQ80358435
C5 blockade with conventional immunosuppression induces long-term graft survival in presensitized recipientsQ81180697
Understanding the causes of kidney transplant failure: the dominant role of antibody-mediated rejection and nonadherenceQ82496190
Indicators of treatment responsiveness to rituximab and plasmapheresis in antibody-mediated rejection after kidney transplantationQ87572187
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseasesQ28131652
How regulatory T cells workQ29614262
CD4+CD25+T regulatory cells in transplantation tolerance; 25 years on.Q30489667
Induced T regulatory cells suppress osteoclastogenesis and bone erosion in collagen-induced arthritis better than natural T regulatory cells.Q33684899
Key role for CD4 T cells during mixed antibody-mediated rejection of renal allograftsQ34024926
Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissueQ34030907
Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditionsQ34082794
In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cellsQ34089068
Predominance of intraglomerular T-bet or GATA3 may determine mechanism of transplant rejectionQ34534855
Control of regulatory T cell lineage commitment and maintenanceQ34658594
Early acceptance of renal allografts in mice is dependent on foxp3(+) cells.Q34805695
Characterization of transfusion-elicited acute antibody-mediated rejection in a rat model of kidney transplantationQ34901573
Cutting edge: all-trans retinoic acid sustains the stability and function of natural regulatory T cells in an inflammatory milieu.Q34994485
Antigen-specific transforming growth factor β-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance.Q35190507
Induced Foxp3(+) regulatory T cells: a potential new weapon to treat autoimmune and inflammatory diseases?Q36378864
An experimental model of acute humoral rejection of renal allografts associated with concomitant cellular rejectionQ36778212
Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized mouse model.Q36903927
TGF-β-Induced Regulatory T Cells Directly Suppress B Cell Responses through a Noncytotoxic MechanismQ36905992
Natural and TGF-beta-induced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each otherQ37233905
Anti-huCD20 antibody therapy for antibody-mediated rejection of renal allografts in a mouse modelQ37252758
CD4+ regulatory T cells in solid organ transplantationQ37794623
Antibody-mediated vascular rejection of kidney allografts: a population-based studyQ38062614
New insights in antibody-mediated rejectionQ38248369
A systematic review of the use of rituximab for desensitization in renal transplantation.Q38260730
Follicular T helper cells and humoral reactivity in kidney transplant patientsQ38923388
IL-17 expression by tubular epithelial cells in renal transplant recipients with acute antibody-mediated rejection.Q39529942
Memory CD4 T Cells Induce Antibody-Mediated Rejection of Renal AllograftsQ42722907
Natural killer cells play a critical role in mediating inflammation and graft failure during antibody-mediated rejection of kidney allograftsQ42784445
Effect of the proteasome inhibitor bortezomib on humoral immunity in two presensitized renal transplant candidatesQ43119566
Foxp3⁺ Treg cells in the inflamed CNS are insensitive to IL-6-driven IL-17 production.Q43535189
Antibody-mediated microcirculation injury is the major cause of late kidney transplant failureQ43918875
Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesionsQ45342440
Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors.Q45972944
Cutting edge: Foxp3+CD4+CD25+ regulatory T cells induced by IL-2 and TGF-beta are resistant to Th17 conversion by IL-6.Q45998381
P304page(s)1334
P577publication date2017-10-16
P1433published inFrontiers in ImmunologyQ27723748
P1476titleIn Vivo Attenuation of Antibody-Mediated Acute Renal Allograft Rejection by Ex Vivo TGF-β-Induced CD4+Foxp3+ Regulatory T Cells
P478volume8

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cites work (P2860)
Q94528590In Situ Immune Profiling of Heart Transplant Biopsies Improves Diagnostic Accuracy and Rejection Risk Stratification
Q64989685Mouse Model Established by Early Renal Transplantation After Skin Allograft Sensitization Mimics Clinical Antibody-Mediated Rejection.
Q58596810Noninvasive and quantitative measurement of C4d deposition for the diagnosis of antibody-mediated cardiac allograft rejection
Q90015597Potential targeted therapy and diagnosis based on novel insight into growth factors, receptors, and downstream effectors in acute kidney injury and acute kidney injury-chronic kidney disease progression
Q88777827Regulatory T Cells and Kidney Transplantation

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