| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Leonardo P Oliveira | Q57059779 |
| P2093 | author name string | Guillermo A Ameer | |
| Michael J Lee | |||
| Russell R Reid | |||
| Tong-Chuan He | |||
| Eric Wang | |||
| Aravind Athiviraham | |||
| Jennifer Moriatis Wolf | |||
| Alexander Li | |||
| Mikhail Pakvasa | |||
| Sami Mostafa | |||
| Alex Alverdy | |||
| Lucy Fu | |||
| P2860 | cites work | Gli regulation by the opposing activities of fused and suppressor of fused | Q22254079 |
| The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation | Q24292169 | ||
| GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter | Q24294866 | ||
| A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling | Q24301647 | ||
| Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation | Q24600279 | ||
| Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors | Q24801427 | ||
| Potential mechanisms underlying the Runx2 induced osteogenesis of bone marrow mesenchymal stem cells | Q26765276 | ||
| Fate decision of mesenchymal stem cells: adipocytes or osteoblasts? | Q26766574 | ||
| Multilineage potential of adult human mesenchymal stem cells | Q27860737 | ||
| The Wnt signaling pathway in development and disease | Q27861019 | ||
| LDL-receptor-related protein 6 is a receptor for Dickkopf proteins | Q28116567 | ||
| Bone morphogenetic protein type IA receptor signaling regulates postnatal osteoblast function and bone remodeling | Q28257036 | ||
| Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells | Q28261235 | ||
| WNT signaling in bone homeostasis and disease: from human mutations to treatments | Q28285090 | ||
| Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs) | Q28508443 | ||
| Regulation of osteoblastogenesis and bone mass by Wnt10b | Q28509048 | ||
| Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction | Q28509243 | ||
| Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development | Q28513519 | ||
| Expression of osterix Is Regulated by FGF and Wnt/β-Catenin Signalling during Osteoblast Differentiation | Q28551666 | ||
| Biochemical characterization and expression analysis of neural thrombospondin-1-like proteins NELL1 and NELL2 | Q28577632 | ||
| Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase | Q28584256 | ||
| The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling | Q28593888 | ||
| Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex | Q28609062 | ||
| NELL-1, an osteoinductive factor, is a direct transcriptional target of Osterix | Q28740434 | ||
| Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study | Q28741604 | ||
| Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts | Q29547605 | ||
| Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor | Q29547912 | ||
| Nuclear localization of beta-catenin by interaction with transcription factor LEF-1 | Q29614379 | ||
| Transcriptional control by the TGF-beta/Smad signaling system | Q29618985 | ||
| Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing. | Q30157916 | ||
| NFAT and Osterix cooperatively regulate bone formation | Q31813054 | ||
| [A potential role for the bone marrow mesenchymal stem cell in the pathogenesis of osteoporosis by ovariectomy in rat]. | Q33236225 | ||
| Bone morphogenic protein 2 directly enhances differentiation of murine osteoclast precursors | Q33719492 | ||
| Synergistic effects of Nell-1 and BMP-2 on the osteogenic differentiation of myoblasts | Q33835530 | ||
| The neuronal EGF-related genes NELL1 and NELL2 are expressed in hemopoietic cells and developmentally regulated in the B lineage | Q33860945 | ||
| Recombinant bone morphogenetic protein-2 induces up-regulation of vascular endothelial growth factor and interleukin 6 in human pre-osteoblasts: role of reactive oxygen species. | Q39691817 | ||
| Wnt proteins promote bone regeneration | Q39709638 | ||
| Brief Report: Human Perivascular Stem Cells and Nel-Like Protein-1 Synergistically Enhance Spinal Fusion in Osteoporotic Rats. | Q40173952 | ||
| Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. | Q40263627 | ||
| Noggin regulation of bone morphogenetic protein (BMP) 2/7 heterodimer activity in vitro | Q40314448 | ||
| BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2. | Q40636491 | ||
| NELL-1 promotes cartilage regeneration in an in vivo rabbit model | Q40718621 | ||
| Sonic hedgehog increases the commitment of pluripotent mesenchymal cells into the osteoblastic lineage and abolishes adipocytic differentiation | Q40787603 | ||
| Bone morphogenetic protein-2 stimulates adipogenic differentiation of mesenchymal precursor cells in synergy with BRL 49653 (rosiglitazone). | Q40871519 | ||
| Reciprocal regulation of adipogenesis by Myc and C/EBP alpha | Q41628463 | ||
| Delivery of lyophilized Nell-1 in a rat spinal fusion model | Q41808911 | ||
| Nell-1 enhances bone regeneration in a rat critical-sized femoral segmental defect model | Q41934910 | ||
| BMP2-induced inflammation can be suppressed by the osteoinductive growth factor NELL-1. | Q41982013 | ||
| High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo | Q42094508 | ||
| Involvement of MAPK signaling molecules and Runx2 in the NELL1-induced osteoblastic differentiation | Q42407001 | ||
| Inhibitory effect 6-gingerol on adipogenesis through activation of the Wnt/β-catenin signaling pathway in 3T3-L1 adipocytes | Q42700309 | ||
| NELL-1 promotes cell adhesion and differentiation via Integrinβ1. | Q42832632 | ||
| Acute airway obstruction associated with the use of bone-morphogenetic protein in cervical spinal fusion | Q44969800 | ||
| WNT/β-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression | Q46277527 | ||
| Bone morphogenetic protein 2 and retinoic acid accelerate in vivo bone formation, osteoclast recruitment, and bone turnover | Q46470442 | ||
| Activation of hedgehog signaling during fracture repair enhances osteoblastic-dependent matrix formation | Q46474876 | ||
| Hedgehog signaling alters adipocyte maturation of human mesenchymal stem cells | Q46765570 | ||
| BMP9 induces osteogenesis and adipogenesis in the immortalized human cranial suture progenitors from the patent sutures of craniosynostosis patients | Q47103852 | ||
| Modulating hedgehog signaling can attenuate the severity of osteoarthritis. | Q51922455 | ||
| The mutational spectrum of the sonic hedgehog gene in holoprosencephaly: SHH mutations cause a significant proportion of autosomal dominant holoprosencephaly. | Q52173272 | ||
| Mild electrical pulse current stimulation upregulates S100A4 and promotes cardiogenesis in MSC and cardiac myocytes coculture monolayer. | Q53148095 | ||
| The osteoinductive properties of Nell-1 in a rat spinal fusion model. | Q53506062 | ||
| Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity. | Q54102658 | ||
| Human NELL1 protein augments constructive tissue remodeling with biologic scaffolds. | Q54444882 | ||
| Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression | Q57129723 | ||
| A Thermoresponsive Biodegradable Polymer with Intrinsic Antioxidant Properties | Q57359665 | ||
| Schnurri-2 Controls BMP-Dependent Adipogenesis via Interaction with Smad Proteins | Q60961756 | ||
| In vitro differentiation of bone and hypertrophic cartilage from periosteal-derived cells | Q70229916 | ||
| Formation of bone and cartilage by marrow stromal cells in diffusion chambers in vivo | Q71328794 | ||
| Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny | Q72143466 | ||
| Downregulation of beta-catenin and transdifferentiation of human osteoblasts to adipocytes under estrogen deficiency | Q81243427 | ||
| Cytokine-Mediated Inflammatory Reaction Following Posterior Cervical Decompression and Fusion Associated With Recombinant Human Bone Morphogenetic Protein-2 | Q85181011 | ||
| Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow | Q33867848 | ||
| Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12. | Q33966602 | ||
| Increasingly complex: new players enter the Wnt signaling network | Q34151763 | ||
| Divergence and convergence of TGF-beta/BMP signaling | Q34229726 | ||
| Purmorphamine activates the Hedgehog pathway by targeting Smoothened. | Q34483948 | ||
| Human NELL-1 expressed in unilateral coronal synostosis | Q34488199 | ||
| Intracellular BMP signaling regulation in vertebrates: pathway or network? | Q34488819 | ||
| Playing with bone and fat. | Q34494766 | ||
| Bone Morphogenetic Protein (BMP) signaling in development and human diseases | Q34512444 | ||
| Craniosynostosis-associated gene nell-1 is regulated by runx2. | Q34574022 | ||
| Conditional deletion of gremlin causes a transient increase in bone formation and bone mass | Q34676851 | ||
| Nell-1 protein promotes bone formation in a sheep spinal fusion model | Q34715389 | ||
| Non-canonical Wnt signaling in Xenopus: regulation of axis formation and gastrulation | Q34758581 | ||
| Transcriptional control of skeletogenesis | Q34820209 | ||
| Effect of pegylation on pharmaceuticals | Q35075776 | ||
| A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells | Q35095530 | ||
| A new function of Nell-1 protein in repressing adipogenic differentiation | Q35194142 | ||
| Nell-1-induced bone regeneration in calvarial defects | Q35222091 | ||
| Nell-1, a key functional mediator of Runx2, partially rescues calvarial defects in Runx2 +/− mice | Q35229979 | ||
| Pharmacokinetics and osteogenic potential of PEGylated NELL-1 in vivo after systemic administration | Q35589250 | ||
| Concise review: adipose-derived stromal cells for skeletal regenerative medicine | Q35880841 | ||
| NELL-1 in the treatment of osteoporotic bone loss. | Q36018565 | ||
| BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk | Q36116637 | ||
| Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells | Q36138491 | ||
| Substrate Stiffness Controls Osteoblastic and Chondrocytic Differentiation of Mesenchymal Stem Cells without Exogenous Stimuli | Q36251332 | ||
| Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages | Q36256208 | ||
| Repair of critical sized cranial defects with BMP9-transduced calvarial cells delivered in a thermoresponsive scaffold | Q36294150 | ||
| Complications of anterior cervical discectomy and fusion using recombinant human bone morphogenetic protein-2. | Q36384446 | ||
| Adverse effects associated with high-dose recombinant human bone morphogenetic protein-2 use in anterior cervical spine fusion | Q36409911 | ||
| Novel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2 | Q36509203 | ||
| NELL-1 injection maintains long-bone quantity and quality in an ovariectomy-induced osteoporotic senile rat model | Q36525894 | ||
| BMP signaling and skeletogenesis | Q36532497 | ||
| Increased swelling complications associated with off-label usage of rhBMP-2 in the anterior cervical spine. | Q36654826 | ||
| Fat's loss is bone's gain | Q36752506 | ||
| Perivascular stem cells: a prospectively purified mesenchymal stem cell population for bone tissue engineering. | Q36861615 | ||
| Vertebral Implantation of NELL-1 Enhances Bone Formation in an Osteoporotic Sheep Model | Q37020010 | ||
| Efficacy of Intraperitoneal Administration of PEGylated NELL-1 for Bone Formation | Q37040159 | ||
| Signal transduction and transcriptional regulation during mesenchymal cell differentiation. | Q37159360 | ||
| A study of the role of nell-1 gene modified goat bone marrow stromal cells in promoting new bone formation | Q37250439 | ||
| The impact of PEGylation on biological therapies | Q37263179 | ||
| Trafficking, development and hedgehog | Q37445191 | ||
| Recombinant human bone morphogenetic protein-2-induced radiculitis in elective minimally invasive transforaminal lumbar interbody fusions: a series review | Q37519236 | ||
| PEGylation for improving the effectiveness of therapeutic biomolecules. | Q37643474 | ||
| Formation of painful seroma and edema after the use of recombinant human bone morphogenetic protein-2 in posterolateral lumbar spine fusions | Q37759995 | ||
| The role of NELL-1, a growth factor associated with craniosynostosis, in promoting bone regeneration | Q37774494 | ||
| Physiology of the aging bone and mechanisms of action of bisphosphonates | Q37892992 | ||
| Use and efficacy of bone morphogenetic proteins in fracture healing. | Q37893542 | ||
| Osteoporosis and the burden of osteoporosis-related fractures. | Q37901461 | ||
| Regulation of bone and cartilage development by network between BMP signalling and transcription factors | Q37976669 | ||
| In osteoporosis, differentiation of mesenchymal stem cells (MSCs) improves bone marrow adipogenesis | Q38071232 | ||
| Review of Signaling Pathways Governing MSC Osteogenic and Adipogenic Differentiation. | Q38177814 | ||
| The Nell-1 growth factor stimulates bone formation by purified human perivascular cells | Q38556628 | ||
| Oligomerization-induced conformational change in the C-terminal region of Nel-like molecule 1 (NELL1) protein is necessary for the efficient mediation of murine MC3T3-E1 cell adhesion and spreading | Q38609022 | ||
| NEL-Like Molecule-1 (Nell1) Is Regulated by Bone Morphogenetic Protein 9 (BMP9) and Potentiates BMP9-Induced Osteogenic Differentiation at the Expense of Adipogenesis in Mesenchymal Stem Cells | Q38715847 | ||
| A Review of the Clinical Side Effects of Bone Morphogenetic Protein-2. | Q38726586 | ||
| Novel hedgehog agonists promote osteoblast differentiation in mesenchymal stem cells | Q38957200 | ||
| Wnt signaling and cellular metabolism in osteoblasts | Q39020338 | ||
| NELL-1-dependent mineralisation of Saos-2 human osteosarcoma cells is mediated via c-Jun N-terminal kinase pathway activation | Q39314285 | ||
| Osterix is required for Sonic hedgehog-induced osteoblastic MC3T3-E1 cell differentiation | Q39339554 | ||
| Wnt/β-catenin signaling plays a distinct role in methyl gallate-mediated inhibition of adipogenesis. | Q39424519 | ||
| P433 | issue | 3 | |
| P921 | main subject | regenerative medicine | Q1061415 |
| mesenchymal stem cell | Q1922379 | ||
| P304 | page(s) | 127-137 | |
| P577 | publication date | 2017-08-03 | |
| P1433 | published in | Genes & Diseases | Q27725779 |
| P1476 | title | Neural EGF-like protein 1 (NELL-1): Signaling crosstalk in mesenchymal stem cells and applications in regenerative medicine | |
| P478 | volume | 4 |
| Q91289594 | Clinical advantages and disadvantages of anabolic bone therapies targeting the WNT pathway |
| Q90468105 | Cumulative inactivation of Nell-1 in Wnt1 expressing cell lineages results in craniofacial skeletal hypoplasia and postnatal hydrocephalus |
| Q64104312 | Investigational growth factors utilized in animal models of spinal fusion: Systematic review |
| Q90698512 | Nell-1 Is a Key Functional Modulator in Osteochondrogenesis and Beyond |
| Q89640740 | The wonders of BMP9: From mesenchymal stem cell differentiation, angiogenesis, neurogenesis, tumorigenesis, and metabolism to regenerative medicine |
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