Conditional deletion of gremlin causes a transient increase in bone formation and bone mass

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Conditional deletion of gremlin causes a transient increase in bone formation and bone mass is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M701317200
P698PubMed publication ID17785465

P50authorErnesto CanalisQ56269284
Stefano ZanottiQ56269901
Anna Smerdel-RamoyaQ117248439
Deena DurantQ117248440
Lisa StadmeyerQ117248442
Aris EconomidesQ37632525
P2093author name stringErnesto Canalis
Elisabetta Gazzerro
P2860cites workGenetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesisQ21145242
Signal transduction of bone morphogenetic protein receptorsQ24302298
Skeletal overexpression of gremlin impairs bone formation and causes osteopeniaQ24314447
The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activitiesQ24314690
Generalized lacZ expression with the ROSA26 Cre reporter strainQ27860837
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cellsQ27860926
Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knotQ28185030
Overexpression of twisted gastrulation inhibits bone morphogenetic protein action and prevents osteoblast cell differentiation in vitroQ44666805
Age-related changes in trabecular architecture differ in female and male C57BL/6J mice.Q51009028
Skeletal Overexpression of Noggin Results in Osteopenia and Reduced Bone FormationQ57936901
High-throughput engineering of the mouse genome coupled with high-resolution expression analysisQ28202486
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signalingQ28240767
Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1Q28251731
Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteinsQ28293474
Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesisQ28506504
Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterningQ28507504
Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factorQ28512188
Identification of drm, a novel gene whose expression is suppressed in transformed cells and which can inhibit growth of normal but not transformed cells in cultureQ28576024
Biosynthesis, post-translation modification, and functional characterization of Drm/GremlinQ28578839
Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the geneQ28776291
Mechanisms of Wnt signaling in developmentQ29547537
A new logic for DNA engineering using recombination in Escherichia coliQ29615202
Secreted antagonists of the Wnt signalling pathwayQ29615521
Validation of peripheral dual-energy X-ray absorptiometry for the measurement of bone mineral in intact and excised long bones of ratsQ31970416
Signal transduction by bone morphogenetic protein receptors: functional roles of Smad proteinsQ33697455
Bone morphogenetic proteins induce gremlin, a protein that limits their activity in osteoblastsQ33927389
Bone morphogenetic protein regulation of early osteoblast genes in human marrow stromal cells is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase signalingQ34049570
RNA interference--2001.Q34174586
Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferationQ34569128
Bone morphogenetic proteins and their antagonistsQ34572394
Regulation of bone mass by Wnt signalingQ34576629
Wnt signaling: a key regulator of bone massQ34583328
Bone morphogenetic proteins, their antagonists, and the skeletonQ35109618
Wnt signaling in osteoblasts and bone diseasesQ35913119
Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivoQ37113932
Bone morphogenetic protein-4 regulates its own expression in cultured osteoblastsQ38316816
Skeletal bone morphogenetic proteins suppress the expression of collagenase-3 by rat osteoblastsQ38328853
Effect of primary and secondary structure of oligodeoxyribonucleotides on the fluorescent properties of conjugated dyesQ39600740
Multiplex quantitative PCR using self-quenched primers labeled with a single fluorophoreQ39600850
Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signalingQ40331060
The orphan receptor tyrosine kinase Ror2 modulates canonical Wnt signaling in osteoblastic cellsQ40511859
Quantitative comparison of DNA looping in vitro and in vivo: chromatin increases effective DNA flexibility at short distancesQ40914602
In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvariaQ41387920
Dkk1-mediated inhibition of Wnt signaling in bone results in osteopeniaQ42801302
Signal transductions induced by bone morphogenetic protein-2 and transforming growth factor-beta in normal human osteoblastic cellsQ42818438
The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways.Q42823613
P433issue43
P407language of work or nameEnglishQ1860
P304page(s)31549-31557
P577publication date2007-09-04
P1433published inJournal of Biological ChemistryQ867727
P1476titleConditional deletion of gremlin causes a transient increase in bone formation and bone mass
P478volume282

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cites work (P2860)
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Q35193538Gremlin, a bone morphogenetic protein antagonist, is a crucial angiogenic factor in pituitary adenoma
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