Interleukin (IL)-18 Binding Protein Deficiency Disrupts Natural Killer Cell Maturation and Diminishes Circulating IL-18.

scientific article published on 28 August 2017

Interleukin (IL)-18 Binding Protein Deficiency Disrupts Natural Killer Cell Maturation and Diminishes Circulating IL-18. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FIMMU.2017.01020
P932PMC publication ID5581878
P698PubMed publication ID28900426

P2093author name stringNora E Sarvetnick
Kristina M Lorenzo-Arteaga
Robert Z Harms
Katie R Ostlund
Austin J Creer
Austin J. Creer
Katie R. Ostlund
Kristina M. Lorenzo-Arteaga
Nora E. Sarvetnick
Robert Z. Harms
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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated functionQ29617462
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Natural killer, but not natural killer T, cells play a necessary role in the promotion of an innate antitumor response induced by IL-18Q78647029
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CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacityQ82310845
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High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding proteinQ84449474
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Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiencyQ35865066
A Study to Investigate the Efficacy and Safety of an Anti-Interleukin-18 Monoclonal Antibody in the Treatment of Type 2 Diabetes MellitusQ35941368
Elevated levels of circulating IL-18BP and perturbed regulation of IL-18 in schizophreniaQ36281530
Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injuryQ36977361
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Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cellsQ37179132
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IRAK and TAK1 are required for IL-18-mediated signalingQ40763167
Consequences of the crosstalk between monocytes/macrophages and natural killer cellsQ42567517
A novel role for interleukin-18 in human natural killer cell death: high serum levels and low natural killer cell numbers in patients with systemic autoimmune diseasesQ43584281
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A novel IL-18BP ELISA shows elevated serum IL-18BP in sepsis and extensive decrease of free IL-18.Q43702638
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IL-18 binding protein fusion construct delays the development of diabetes in adoptive transfer and cyclophosphamide-induced diabetes in NOD mouseQ48550682
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In vivo developmental stages in murine natural killer cell maturation.Q52120129
Transferrin‘ activation: Bonding with transferrin receptors tunes KLRG1 functionQ57257146
NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1Q57374973
Combined Stimulation with Interleukin-18 and CpG Induces Murine Natural Killer Dendritic Cells to Produce IFN-γ and Inhibit Tumor GrowthQ58034330
The natural soluble form of IL-18 receptor beta exacerbates collagen-induced arthritis via modulation of T-cell immune responsesQ64375431
ATP acts as an agonist to promote stimulus-induced secretion of IL-1 beta and IL-18 in human bloodQ73086270
P4510describes a project that usesImageJQ1659584
P921main subjectprotein deficiencyQ18966920
P304page(s)1020
P577publication date2017-08-28
P1433published inFrontiers in ImmunologyQ27723748
P1476titleInterleukin (IL)-18 Binding Protein Deficiency Disrupts Natural Killer Cell Maturation and Diminishes Circulating IL-18.
P478volume8

Reverse relations

cites work (P2860)
Q52709434A new checkpoint for Natural Killer cell activation.
Q58580465Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes
Q90476077CD83+ CCR7+ NK cells induced by interleukin 18 by dendritic cells promote experimental autoimmune uveitis
Q57112108Cisplatin-Induced Rodent Model of Kidney Injury: Characteristics and Challenges
Q64275741Interleukin-18 in Health and Disease
Q90841067Remifentanil upregulates hepatic IL-18 binding protein (IL-18BP) expression through transcriptional control
Q47285858The family of the interleukin-1 receptors

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