| P50 | author | EFSA Panel On Contaminants In The Food Chain | Q62579451 |
| P2860 | cites work | Determination of nitrofuran metabolites in shrimp by high performance liquid chromatography with fluorescence detection and liquid chromatography-tandem mass spectrometry using a new derivatization reagent. | Q53640945 |
| | Non-disjunction and crossing-over induced by pharmaceutical drugs in Aspergillus nidulans | Q53761057 |
| | DNA damage, prophage induction and mutation by furazolidone. | Q53807491 |
| | Efficacy and safety profile of long-term nitrofurantoin in urinary infections: 18 years' experience. | Q54120193 |
| | Multi-residue monitoring for the simultaneous determination of five nitrofurans (furazolidone, furaltadone, nitrofurazone, nitrofurantoine, nifursol) in poultry muscle tissue through the detection of their five major metabolites (AOZ, AMOZ, SEM, AHD | Q54527772 |
| | The mutational specificity of furazolidone in the lacI gene of Escherichia coli. | Q54578716 |
| | Performance evaluation of commercial ELISA kits for screening of furazolidone and furaltadone residues in fish. | Q54755829 |
| | Enzyme immunoassay for semicarbazide—The nitrofuran metabolite and food contaminant | Q58412269 |
| | Stability studies of the metabolites of nitrofuran antibiotics during storage and cooking | Q58412271 |
| | Monoclonal antibody-based ELISA for the quantification of nitrofuran metabolite 3-amino-2-oxazolidinone in tissues using a simplified sample preparation | Q58412273 |
| | Nitrofuran antibiotic residues in pork | Q58412275 |
| | Prevention of Foetal Development by Enzyme Inhibition | Q58936944 |
| | Evaluation of 60 chemicals in a preliminary developmental toxicity test | Q23910614 |
| | Furazolidone-based therapies for Helicobacter pylori infection: a pooled-data analysis | Q26823010 |
| | Generation of furazolidone radical anion and its inhibition by glutathione | Q28326780 |
| | Effect of acid secretion blockade by omeprazole on the relative bioavailability of orally administered furazolidone in healthy volunteers | Q28345560 |
| | Semicarbazide Formation in Azodicarbonamide-Treated Flour: A Model Study | Q30050281 |
| | N-(4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine carboxamide (GF120918) as a chemical ATP-binding cassette transporter family G member 2 (Abcg2) knockout model to study nitrofurantoin t | Q33370268 |
| | Liquid chromatography-tandem mass spectrometry for the determination of protein-bound residues in shrimp dosed with nitrofurans | Q33434272 |
| | Determination of nitrofuran residues in milk of dairy cows using liquid chromatography-tandem mass spectrometry | Q33436756 |
| | Hepatic injury associated with the use of nitrofurans: a clinicopathological study of 52 reported cases | Q34176531 |
| | A compilation of LD50 values in newborn and adult animals | Q34235534 |
| | Neonatal outcomes after gestational exposure to nitrofurantoin | Q34324002 |
| | Biotransformation reactions of five-membered aromatic heterocyclic rings | Q34565087 |
| | Bioactivation and hepatotoxicity of nitroaromatic drugs | Q34577682 |
| | Adverse reactions of nitrofurantoin, trimethoprim and sulfamethoxazole in children | Q35833314 |
| | The effect of nitrofurazone on the testes and accessory sex organs of normal rats and rats bearing the Walker carcinoma 256. | Q36134197 |
| | Semicarbazide: occurrence in food products and state-of-the-art in analytical methods used for its determination | Q36158076 |
| | Dietary exposure assessments for children in europe (the EXPOCHI project): rationale, methods and design | Q36217652 |
| | The ABCG2 C421A polymorphism does not affect oral nitrofurantoin pharmacokinetics in healthy Chinese male subjects. | Q36803379 |
| | Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States | Q36844723 |
| | Aquaculture practices and potential human health risks: current knowledge and future priorities | Q37195452 |
| | In vivo and in vitro metabolic studies of furazolidone: a risk evaluation | Q37804271 |
| | Shape and steepness of toxicological dose-response relationships of continuous endpoints | Q38164132 |
| | Determination of the metabolites of nitrofuran antibiotics in animal tissue by high-performance liquid chromatography-tandem mass spectrometry | Q38436661 |
| | Stability of nitrofuran residues during honey processing and nitrofuran removal by macroporous adsorption resins | Q38449101 |
| | The influence of food on nitrofurantoin bioavailability | Q39102738 |
| | Metabolic activation of nitrofurantoin—possible implications for carcinogenesis | Q39251169 |
| | Furazolidone induced oxidative DNA damage via up-regulating ROS that caused cell cycle arrest in human hepatoma G2 cells | Q39613446 |
| | Nitrofurantoin--current concepts | Q39649660 |
| | The metabolic activation of nitroheterocyclic therapeutic agents | Q39654207 |
| | In vivo inhibition of BCRP/ABCG2 mediated transport of nitrofurantoin by the isoflavones genistein and daidzein: a comparative study in Bcrp1 (-/-) mice. | Q39683616 |
| | Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells | Q39745735 |
| | The food contaminant semicarbazide acts as an endocrine disrupter: Evidence from an integrated in vivo/in vitro approach | Q39793662 |
| | Genotoxic activity and potency of 135 compounds in the Ames reversion test and in a bacterial DNA-repair test | Q40178468 |
| | Comparative genotoxic evaluation of 2-furylethylenes and 5-nitrofurans by using the comet assay in TK6 cells | Q40437338 |
| | The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin. | Q40458879 |
| | Mechanism of carcinogenesis induced by a veterinary antimicrobial drug, nitrofurazone, via oxidative DNA damage and cell proliferation | Q40503464 |
| | Basolateral active uptake of nitrofurantoin in the CIT3 cell culture model of lactation | Q40646724 |
| | Mutagenic evaluation of nitrofuran derivatives in Salmonella typhimurium, by the micronucleus test, and by in vivo cytogenetics | Q40783658 |
| | New reagent for trace determination of protein-bound metabolites of nitrofurans in shrimp using liquid chromatography with diode array detector | Q46130353 |
| | Effects of the food contaminant semicarbazide following oral administration in juvenile Sprague-Dawley rats. | Q46180539 |
| | Nitrofurazone: Kinetics and oxidative stress in the singlepass isolated perfused rat liver | Q46270885 |
| | Nitrofuran antibiotic metabolites detected at parts per million concentrations in retina of pigs--a new matrix for enhanced monitoring of nitrofuran abuse | Q46388520 |
| | Residue depletion of nitrofuran drugs and their tissue-bound metabolites in channel catfish (Ictalurus punctatus) after oral dosing | Q46432641 |
| | Analysis of nifursol residues in turkey and chicken meat using liquid chromatography-tandem mass spectrometry | Q46432806 |
| | Quantitative determination of four nitrofuran metabolites in meat by isotope dilution liquid chromatography-electrospray ionisation-tandem mass spectrometry | Q46448905 |
| | Microsomal oxidative stress induced by NADPH is inhibited by nitrofurantoin redox biotranformation. | Q46450301 |
| | Determination of nifursol metabolites in poultry muscle and liver tissue. Development and validation of a confirmatory method | Q46455894 |
| | Involvement of active oxygen species in protein and oligonucleotide degradation induced by nitrofurans | Q46466584 |
| | Comparison of genomic damage caused by 5-nitrofurantoin in young and adult mice using the in vivo micronucleus assay | Q46478669 |
| | In-house validation of an ELISA method for screening of semicarbazide in eggs | Q46496439 |
| | Rapid determination of chloramphenicol residues in milk powder by liquid chromatography-elektrospray ionization tandem mass spectrometry | Q46514946 |
| | Kinetics of semicarbazide and nitrofurazone in chicken eggs and egg powders | Q46592524 |
| | Residues of nitrofuran antibiotic parent compounds and metabolites in eyes of broiler chickens | Q46600577 |
| | Depletion of four nitrofuran antibiotics and their tissue-bound metabolites in porcine tissues and determination using LC-MS/MS and HPLC-UV. | Q46600902 |
| | The occurrence of nitrofuran metabolites in the tissues of chickens exposed to very low dietary concentrations of the nitrofurans | Q46600943 |
| | Transfer of nitrofuran residues from parent broiler breeder chickens to broiler progeny | Q46623241 |
| | Determination of nitrofuran metabolites in poultry muscle and eggs by liquid chromatography-tandem mass spectrometry | Q46629967 |
| | Determination of nitrofuran metabolites in milk by liquid chromatography-electrospray ionization tandem mass spectrometry | Q46749582 |
| | Development of an indirect competitive ELISA for the detection of furazolidone marker residue in animal edible tissues | Q46764305 |
| | Sister chromatid exchanges in peripheral lymphocytes of urinary tract infection treated with nitrofurantoin | Q46782043 |
| | ELISA for semicarbazide and its application for screening in food contamination | Q46799714 |
| | Evaluation of the FoodEx, the food classification system applied to the development of the EFSA Comprehensive European Food Consumption Database | Q47149492 |
| | Use of the EFSA Comprehensive European Food Consumption Database in Exposure Assessment | Q47149547 |
| | Scientific opinion on genotoxicity testing strategies applicable to food and feed safety assessment | Q47150597 |
| | Guidance on selected default values to be used by the EFSA Scientific Committee, Scientific Panels and Units in the absence of actual measured data | Q47151301 |
| | Guidance on methodological principles and scientific methods to be taken into account when establishing Reference Points for Action (RPAs) for non-allowed pharmacologically active substances present in food of animal origin | Q47153236 |
| | Study on the role of glutathione in the biotransformation and toxicity of furazolidone using pig hepatocytes | Q47790267 |
| | The use of pig hepatocytes for cytotoxicity studies of veterinary drugs: A comparative study with furazolidone and other nitrofurans | Q47790519 |
| | Quantitative studies of the metabolism of furazolidone by rat liver microsomes | Q47793234 |
| | Determination of furaltadone and nifursol residues in poultry eggs by liquid chromatography-electrospray ionization tandem mass spectrometry. | Q47929227 |
| | Teratogenic effect of semicarbazide in Wistar rats | Q48388805 |
| | Investigation into the possible natural occurence of semicarbazide in Macrobrachium rosenbergii prawns | Q49073093 |
| | Biotransformation of furaltadone by pig hepatocytes and Salmonella typhimurium TA 100 bacteria, and the formation of protein-bound metabolites | Q50147557 |
| | On the induction of umu gene expression in Salmonella typhimurium strain TA1535/pSK1002 by some nitrofurans | Q50176082 |
| | The elimination of furazolidone and its open-chain cyano-derivative from adult swine | Q50200104 |
| | Mutagenicity of nitrofurans in Salmonella typhimurium TA98, TA98NR and TA98/1,8-DNP6. | Q50200663 |
| | Nitrofuran mutagenicity: induction of frameshift mutations | Q50202578 |
| | Study of 106 organic and inorganic compounds in the Salmonella/microsome test | Q50217672 |
| | Mutagenic activity of carcinogenic and noncarcinogenic nitrofurans and of urine of rats fed these compounds | Q50227084 |
| | Activation of nitrofurantoin to a mutagen by rat liver nitroreductase | Q50227363 |
| | Mutagenicities of nitrofuran derivatives on a bacterial tester strain with an R factor plasmid | Q50228220 |
| | Mutagen screening with bacteria: Niridazole and nitrofurans | Q50229561 |
| | Organ-targeted mutagenicity of nitrofurantoin in Big Blue transgenic mice | Q50476896 |
| | Analysis of veterinary drug residues in fish and shrimp composites collected during the Canadian Total Diet Study, 1993-2004. | Q50705010 |
| | A novel chemiluminescent ELISA for detecting furaltadone metabolite, 3-amino-5-morpholinomethyl-2-oxazolidone (AMOZ) in fish, egg, honey and shrimp samples. | Q50870016 |
| | Chronic toxicity and carcinogenicity of semicarbazide hydrochloride in Wistar Hannover GALAS rats. | Q51119355 |
| | Determinations of residual furazolidone and its metabolite, 3-amino-2-oxazolidinone (AOZ), in fish feeds by HPLC-UV and LC-MS/MS, respectively. | Q51713296 |
| | Studies on the induction of sex-linked recessive lethal mutations in Drosophila melanogaster by nitroheterocyclic compounds. | Q52527458 |
| | Validation of a confirmatory method for the determination of residues of four nitrofurans in egg by liquid chromatography-tandem mass spectrometry with the software InterVal. | Q52926806 |
| | Detection of chemical mutagens by the dominant lethal assay in the mouse | Q52966412 |
| | Chronic toxicity and oncogenicity studies of Macrodantin in Sprague-Dawley rats. | Q53508453 |
| | Oncogenicity study of macrodantin in Swiss mice. | Q53510302 |
| | Toxicity and carcinogenicity of nitrofurazone in F344/N rats and B6C3F1 mice. | Q53516947 |
| | Alkaline DNA fragmentation, DNA disentanglement evaluated viscosimetrically and sister chromatid exchanges, after treatment in vivo with nitrofurantoin. | Q53558716 |
| | Use of a simplified fluctuation test to detect and characterize mutagenesis by nitrofurans | Q40802309 |
| | Metabolism of furazolidone: alternative pathways and modes of toxicity in different cell lines | Q40911975 |
| | A contribution to safety assessment of veterinary drug residues: in vitro/ex vivo studies on the intestinal toxicity and transport of covalently bound residues | Q40938917 |
| | Chromosomal aberration tests on 29 chemicals combined with S9 mix in vitro | Q41039378 |
| | The application of mitotic gene conversion in Saccharomyces cervisiae in a pattern of four assays, in vitro and in vivo, for mutagenicity testing | Q41085559 |
| | The effect of nitrofurans on mitosis, chromosome breakage and sister-chromatid exchanges in human peripheral lymphocytes | Q41514211 |
| | Distribution of nitroreductive activity toward nilutamide in rat. | Q42171999 |
| | Reversible interaction of a reactive intermediate derived from furazolidone with glutathione and protein | Q42215004 |
| | Identification of a reactive intermediate of furazolidone formed by swine liver microsomes | Q42220480 |
| | Metabolism in vivo of furazolidone: evidence for formation of an open-chain carboxylic acid and alpha-ketoglutaric acid from the nitrofuran in rats | Q42250381 |
| | Reduction of nitroheterocyclic compounds by mammalian tissues in vivo | Q42260236 |
| | Adverse reactions to nitrofurantoin. Analysis of 921 reports | Q42273250 |
| | Nitrofurantoin disposition | Q42670848 |
| | Chemical structure-related mechanisms underlying in vivo genotoxicity induced by nitrofurantoin and its constituent moieties in gpt delta rats | Q42702282 |
| | Absorption of a mutagenic metabolite released from protein-bound residues of furazolidone. | Q42730151 |
| | Drug-induced autoimmune hepatitis: clinical characteristics and prognosis. | Q43050091 |
| | Tissue depletion and concentration correlations between edible tissues and biological fluids of 3-amino-2-oxazolidinone in pigs fed with a furazolidone-medicated feed | Q43073679 |
| | Application of a modified enzyme-linked immunosorbent assay for 3-amino-2-oxazolidinone residue in aquatic animals | Q43110414 |
| | Cyano metabolite as a biomarker of nitrofurazone in channel catfish | Q43232988 |
| | Evaluation of genotoxic effects of semicarbazide on cultured human lymphocytes and rat bone marrow | Q43264051 |
| | Milk secretion of nitrofurantoin, as a specific BCRP/ABCG2 substrate, in assaf sheep: modulation by isoflavones | Q43276464 |
| | High-performance liquid chromatography with fluorescence detection for the determination of nitrofuran metabolites in pork muscle | Q43309415 |
| | Development of a lateral flow immunoassay (LFA) strip for the rapid detection of 1-aminohydantoin in meat samples | Q43341560 |
| | Carbamylhydrazine hydrochloride as a lung and blood vessel tumour inducer in Swiss mice | Q43549251 |
| | Nitrofurantoin and congenital abnormalities | Q43553334 |
| | alpha 2u-Globulin nephropathy, renal cell proliferation, and dosimetry of inhaled tert-butyl alcohol in male and female F-344 rats | Q43569685 |
| | Active transport of nitrofurantoin into human milk | Q43636328 |
| | Testicular toxicity of nitrofurazone causing germ cell apoptosis in rats. | Q43731287 |
| | Evaluation of the residues of furazolidone and its metabolite, 3-amino-2-oxazolidinone (AOZ), in eggs | Q43772681 |
| | Revisiting the interaction of the radical anion metabolite of nitrofurantoin with glutathione | Q43826162 |
| | Cytogenetic analysis of peripheral blood lymphocytes of children treated with nitrofurantoin for recurrent urinary tract infection | Q43830262 |
| | Nitrofurazone induces non-regenerative hepatocyte proliferation in rats | Q43942188 |
| | The use of pig hepatocytes to study the nature of protein-bound metabolites of furazolidone: a new analytical method for their detection | Q44298383 |
| | Microwave-assisted derivatisation and LC-MS/MS determination of nitrofuran metabolites in farm-raised prawns (Penaeus monodon). | Q44308140 |
| | Disposition of 3-(4-cyano-2-oxobutylidene amino)-2-oxazolidone, a cyano-metabolite of furazolidone, in furazolidone-treated grouper | Q44353503 |
| | Postmortal degradation of furazolidone and furaltadone in edible tissues of calves | Q44375262 |
| | Carcinogenic semicarbazide induces sequence-specific DNA damage through the generation of reactive oxygen species and the derived organic radicals | Q44403107 |
| | Evaluation of treatment and prophylaxis with nitrofurans and comparison with alternative antimicrobial agents in experimental Salmonella enterica Serovar enteritidis infection in chicks | Q44483936 |
| | Monoclonal antibody-based fluorescence polarization immunoassay for high throughput screening of furaltadone and its metabolite AMOZ in animal feeds and tissues | Q44491366 |
| | Implications of the use of semicarbazide as a metabolic target of nitrofurazone contamination in coated products | Q44743135 |
| | Semicarbazide is a minor thermal decomposition product of azodicarbonamide used in the gaskets of certain food jars | Q44773093 |
| | Formation of semicarbazide (SEM) in food by hypochlorite treatment: is SEM a specific marker for nitrofurazone abuse? | Q44942135 |
| | Analysis of matrix-bound nitrofuran residues in worldwide-originated honeys by isotope dilution high-performance liquid chromatography-tandem mass spectrometry | Q45021187 |
| | In-house validation of liquid chromatography tandem mass spectrometry for determination of semicarbazide in eggs and stability of analyte in matrix | Q45074501 |
| | Nitrofurazone--genotoxicity studies in mammalian cells in vitro and in vivo | Q45077299 |
| | Semicarbazide is not genotoxic in the flow cytometry-based micronucleus assay in vivo | Q45189944 |
| | Novel source of semicarbazide: levels of semicarbazide in cooked crayfish samples determined by LC/MS/MS. | Q45235745 |
| | Detection of 3-amino-2-oxazolidinone (AOZ), a tissue-bound metabolite of the nitrofuran furazolidone, in prawn tissue by enzyme immunoassay | Q45235751 |
| | Residue analyses and exposure assessment of the Irish population to nitrofuran metabolites from different food commodities in 2009-2010. | Q45731644 |
| | A ninety-day toxicity study of semicarbazide hydrochloride in Wistar Hannover GALAS rats. | Q45926056 |
| | Development and residue screening of the furazolidone metabolite, 3-amino-2-oxazolidinone (AOZ), in cultured fish by an enzyme-linked immunosorbent assay. | Q45968971 |
| | Oxidative Metabolites of 5-Nitrofurans | Q46111564 |
| | Multidetermination of four nitrofurans in animal feeds by a sensitive and simple enzyme-linked immunosorbent assay | Q46115097 |
| P433 | issue | 6 | |
| P304 | page(s) | 4140 | |
| P577 | publication date | 2015-06-01 | |
| P1433 | published in | EFSA Journal | Q56298557 |
| P1476 | title | Scientific Opinion on nitrofurans and their metabolites in food | |
| P478 | volume | 13 | |