review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Jason A Stewart | |
Yilin Wang | |||
Stephanie M Ackerson | |||
Percy Logan Schuck | |||
P2860 | cites work | Mammalian telomeres end in a large duplex loop | Q22009893 |
RTEL1 maintains genomic stability by suppressing homologous recombination | Q24309568 | ||
RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway | Q24310294 | ||
Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes | Q24310347 | ||
OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation | Q24319072 | ||
The human CST complex is a terminator of telomerase activity | Q24339504 | ||
Finding the end: recruitment of telomerase to telomeres | Q24606549 | ||
TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo | Q24606587 | ||
The telomere syndromes | Q24632444 | ||
Structure and function of the telomeric CST complex | Q26745414 | ||
G-quadruplexes and helicases | Q26765428 | ||
The short and long telomere syndromes: paired paradigms for molecular medicine | Q26800388 | ||
Controlling DNA replication origins in response to DNA damage - inhibit globally, activate locally | Q26864402 | ||
Structure of the full-length human RPA14/32 complex gives insights into the mechanism of DNA binding and complex formation | Q27648935 | ||
Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres | Q27658652 | ||
Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α | Q27664722 | ||
Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70 | Q27675212 | ||
Cdc13 OB2 Dimerization Required for Productive Stn1 Binding and Efficient Telomere Maintenance | Q27675213 | ||
Structure of the Human Telomeric Stn1-Ten1 Capping Complex | Q27678920 | ||
Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance | Q27930358 | ||
The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein | Q27931011 | ||
Multiple pathways regulate 3' overhang generation at S. cerevisiae telomeres. | Q27931150 | ||
PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M phase | Q27932588 | ||
Cdc13 delivers separate complexes to the telomere for end protection and replication | Q27933636 | ||
Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13. | Q27937259 | ||
The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo | Q27937905 | ||
Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13 | Q27938764 | ||
RPA-like proteins mediate yeast telomere function | Q27939798 | ||
Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint | Q27939822 | ||
Preventing replication fork collapse to maintain genome integrity | Q28083804 | ||
Replication stress in Mammalian cells and its consequences for mitosis | Q28087011 | ||
THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS | Q28202269 | ||
Nucleic acid recognition by OB-fold proteins | Q28211138 | ||
Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism | Q28245231 | ||
The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity | Q28278112 | ||
Cell biology of disease: Telomeropathies: an emerging spectrum disorder | Q28385689 | ||
Online survival analysis software to assess the prognostic value of biomarkers using transcriptomic data in non-small-cell lung cancer | Q28393146 | ||
The telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with G-Tails, and unfolds higher-order G-tail structures | Q28484817 | ||
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry | Q28509466 | ||
Apollo contributes to G overhang maintenance and protects leading-end telomeres | Q28585996 | ||
A DNA polymerase-{alpha}⋅primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells | Q28592218 | ||
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion | Q28594209 | ||
BLM helicase facilitates telomere replication during leading strand synthesis of telomeres | Q28771475 | ||
Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation | Q28854371 | ||
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis | Q28943334 | ||
The serial cultivation of human diploid cell strains | Q29547356 | ||
Mechanism of eukaryotic homologous recombination | Q29547709 | ||
A dynamic model for replication protein A (RPA) function in DNA processing pathways | Q29614213 | ||
How shelterin protects mammalian telomeres | Q29615744 | ||
Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis | Q36033609 | ||
NEK6-mediated phosphorylation of human TPP1 regulates telomere length through telomerase recruitment | Q36072262 | ||
The Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability. | Q36075263 | ||
Human RecQ helicases in DNA repair, recombination, and replication. | Q36101160 | ||
STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function. | Q36150049 | ||
Human CST abundance determines recovery from diverse forms of DNA damage and replication stress | Q36182484 | ||
Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament | Q36208716 | ||
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans | Q36435865 | ||
A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM-p53 signaling | Q36549512 | ||
The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex | Q36612346 | ||
Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk | Q36618894 | ||
Phosphorylation of TPP1 regulates cell cycle-dependent telomerase recruitment | Q36747492 | ||
Replication fork stalling at natural impediments | Q36755308 | ||
Mutations in the telomere capping complex in bone marrow failure and related syndromes | Q36862320 | ||
Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers | Q36926996 | ||
Yeast telomere capping protein Stn1 overrides DNA replication control through the S phase checkpoint | Q37114775 | ||
Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects. | Q37178997 | ||
Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia | Q37225819 | ||
Human TEN1 maintains telomere integrity and functions in genome-wide replication restart | Q37233984 | ||
CST for the grand finale of telomere replication. | Q37260942 | ||
Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry. | Q37272064 | ||
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication | Q37297007 | ||
Inevitability and containment of replication errors for eukaryotic genome lengths spanning megabase to gigabase. | Q37304838 | ||
Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells | Q37304981 | ||
Molecular basis of telomere syndrome caused by CTC1 mutations | Q37362550 | ||
Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease | Q37388520 | ||
A genome-wide association study yields five novel thyroid cancer risk loci | Q37652005 | ||
Pathways of mammalian replication fork restart. | Q37788950 | ||
How dormant origins promote complete genome replication | Q37884997 | ||
RecQ Helicases: Conserved Guardians of Genomic Integrity. | Q38060579 | ||
TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends | Q38322972 | ||
DNA replication origin activation in space and time | Q38496732 | ||
Replicating through telomeres: a means to an end. | Q38549970 | ||
DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation | Q38781891 | ||
Tpz1TPP1 SUMOylation reveals evolutionary conservation of SUMO-dependent Stn1 telomere association | Q35187409 | ||
Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features | Q35195952 | ||
Role of STN1 and DNA polymerase α in telomere stability and genome-wide replication in Arabidopsis. | Q35316062 | ||
The CDC13-STN1-TEN1 complex stimulates Pol α activity by promoting RNA priming and primase-to-polymerase switch | Q35516945 | ||
Stn1 is critical for telomere maintenance and long-term viability of somatic human cells. | Q35527169 | ||
Dyskeratosis congenita as a disorder of telomere maintenance | Q35529338 | ||
Reversal of human cellular senescence: roles of the p53 and p16 pathways | Q35561999 | ||
Whole exome sequencing in an Indian family links Coats plus syndrome and dextrocardia with a homozygous novel CTC1 and a rare HES7 variation | Q35576893 | ||
Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulation | Q35667156 | ||
Identification of the single-strand telomeric DNA binding domain of the Saccharomyces cerevisiae Cdc13 protein | Q35775759 | ||
SUMOylation regulates telomere length homeostasis by targeting Cdc13. | Q35794091 | ||
ATR cooperates with CTC1 and STN1 to maintain telomeres and genome integrity in Arabidopsis | Q35891199 | ||
A POT1 mutation implicates defective telomere end fill-in and telomere truncations in Coats plus | Q35969867 | ||
Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma | Q36019187 | ||
CTC1 Mutations in a patient with dyskeratosis congenita. | Q36028290 | ||
Getting it done at the ends: Pif1 family DNA helicases and telomeres | Q38846111 | ||
Moonlighting at replication forks - a new life for homologous recombination proteins BRCA1, BRCA2 and RAD51. | Q39082252 | ||
Telomerase Mechanism of Telomere Synthesis | Q39111969 | ||
DNA Replication Origins and Fork Progression at Mammalian Telomeres | Q39204805 | ||
Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in | Q39281825 | ||
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress | Q39593027 | ||
Molecular steps of G-overhang generation at human telomeres and its function in chromosome end protection | Q39678675 | ||
R-loops and initiation of DNA replication in human cells: a missing link? | Q40009006 | ||
Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress. | Q40035632 | ||
Characterizing and controlling intrinsic biases of lambda exonuclease in nascent strand sequencing reveals phasing between nucleosomes and G-quadruplex motifs around a subset of human replication origins | Q40174771 | ||
The chromatin environment shapes DNA replication origin organization and defines origin classes | Q40330362 | ||
Cdc13 both positively and negatively regulates telomere replication | Q40423693 | ||
Binding and partial denaturing of G-quartet DNA by Cdc13p of Saccharomyces cerevisiae | Q40776851 | ||
Purification and properties of an accessory protein for DNA polymerase alpha/primase | Q41725303 | ||
Functional characterization of human CTC1 mutations reveals novel mechanisms responsible for the pathogenesis of the telomere disease Coats plus | Q41984776 | ||
FEN1 ensures telomere stability by facilitating replication fork re-initiation | Q42043800 | ||
Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST. | Q42230020 | ||
Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress | Q43919251 | ||
A genome-wide approach to comparative oncology: high-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations | Q44866410 | ||
The mechanism of action of an accessory protein for DNA polymerase alpha/primase | Q46199480 | ||
Dynamic DNA binding, junction recognition and G4 melting activity underlie the telomeric and genome-wide roles of human CST. | Q47639251 | ||
STN1-POLA2 interaction provides a basis for primase-pol α stimulation by human STN1. | Q47766830 | ||
Monitoring Replication Protein A (RPA) dynamics in homologous recombination through site-specific incorporation of non-canonical amino acids | Q47767023 | ||
Human CST Prefers G-Rich but Not Necessarily Telomeric Sequences. | Q48096332 | ||
Cerebro-retinal microangiopathy with calcifications and cysts due to recessive mutations in the CTC1 gene | Q48246756 | ||
Cerebroretinal microangiopathy with calcifications and cysts associated with CTC1 and NDP mutations. | Q48262406 | ||
spRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast. | Q48336594 | ||
Hayflick, his limit, and cellular ageing. | Q48774640 | ||
Unprotected Replication Forks Are Converted into Mitotic Sister Chromatid Bridges. | Q50670452 | ||
Sequential phosphorylation of CST subunits by different cyclin-Cdk1 complexes orchestrate telomere replication. | Q50923832 | ||
Cerebroretinal microangiopathy with calcifications and cysts (CRMCC). | Q52852392 | ||
Long telomeres and cancer risk among 95 568 individuals from the general population. | Q52855805 | ||
The fission yeast Taz1 protein protects chromosomes from Ku-dependent end-to-end fusions | Q64388249 | ||
Role for BLM in replication-fork restart and suppression of origin firing after replicative stress | Q80551000 | ||
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer | Q30252854 | ||
Protection of telomeres by a conserved Stn1-Ten1 complex | Q33294968 | ||
MERISTEM DISORGANIZATION1 encodes TEN1, an essential telomere protein that modulates telomerase processivity in Arabidopsis | Q33355631 | ||
STN1 protects chromosome ends in Arabidopsis thaliana | Q33390929 | ||
Structure prediction-driven genetics in Saccharomyces cerevisiae identifies an interface between the t-RPA proteins Stn1 and Ten1 | Q33531384 | ||
Fission yeast Stn1 is crucial for semi-conservative replication at telomeres and subtelomeres | Q33554092 | ||
CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance | Q33636085 | ||
Association between previously identified loci affecting telomere length and coronary heart disease (CHD) in Han Chinese population | Q33698282 | ||
CpG islands as genomic footprints of promoters that are associated with replication origins. | Q33744783 | ||
CTC1 increases the radioresistance of human melanoma cells by inhibiting telomere shortening and apoptosis | Q33747685 | ||
Protection and replication of telomeres in fission yeast | Q33789158 | ||
Continued primer synthesis at stalled replication forks contributes to checkpoint activation. | Q33799163 | ||
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology | Q33927045 | ||
Sequence-specific binding to telomeric DNA is not a conserved property of the Cdc13 DNA binding domain | Q33930774 | ||
Structural anatomy of telomere OB proteins | Q34032182 | ||
Xenopus laevis Ctc1-Stn1-Ten1 (xCST) protein complex is involved in priming DNA synthesis on single-stranded DNA template in Xenopus egg extract | Q34075356 | ||
Evolution of CST function in telomere maintenance | Q34130588 | ||
CST meets shelterin to keep telomeres in check | Q34137320 | ||
Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus | Q34248892 | ||
Mutations in CTC1, encoding the CTS telomere maintenance complex component 1, cause cerebroretinal microangiopathy with calcifications and cysts | Q34258372 | ||
Human CST promotes telomere duplex replication and general replication restart after fork stalling | Q34292284 | ||
Causes and consequences of replication stress | Q34394094 | ||
SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast | Q34414175 | ||
Replication protein A: single-stranded DNA's first responder: dynamic DNA-interactions allow replication protein A to direct single-strand DNA intermediates into different pathways for synthesis or repair | Q34435942 | ||
Human CST has independent functions during telomere duplex replication and C-strand fill-in | Q34473074 | ||
Rescue from replication stress during mitosis | Q34550677 | ||
Cerebroretinal microangiopathy with calcifications and cysts. | Q34561957 | ||
DNA end resection--unraveling the tail | Q34612802 | ||
TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice | Q34619809 | ||
Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length | Q34785081 | ||
The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain | Q34993950 | ||
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice | Q34997279 | ||
The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation. | Q35179269 | ||
P921 | main subject | genome stability | Q98655700 |
P304 | page(s) | 1564-1586 | |
P577 | publication date | 2018-03-01 | |
P1433 | published in | Frontiers in Bioscience | Q5506062 |
P1476 | title | Emerging roles of CST in maintaining genome stability and human disease | |
P478 | volume | 23 |
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