A membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymes

scientific article published on 20 December 2017

A membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.RA117.000926
P932PMC publication ID5798302
P698PubMed publication ID29263090

P50authorQisheng ZhangQ84143071
P2093author name stringT Kendall Harden
Xiaoyang Wang
Matthew Barrett
John Sondek
Nicole Hajicek
Stuart Endo-Streeter
Weigang Huang
Christian Wohlfeld
Jarod Waybright
P2860cites workGeneral and Versatile Autoinhibition of PLC IsozymesQ27651494
Phosphoinositides in cell regulation and membrane dynamicsQ27861051
The phospholipase C isozymes and their regulationQ28261474
Regulation of phosphoinositide-specific phospholipase CQ28366528
Catalysis by phospholipase C delta1 requires that Ca2+ bind to the catalytic domain, but not the C2 domainQ28573172
Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q.Q30497892
Chemical and physiological characterization of fluo-4 Ca(2+)-indicator dyesQ30855902
Mechanism of phosphorylation-induced activation of phospholipase C-gamma isozymesQ34135196
Membrane-induced allosteric control of phospholipase C-β isozymesQ34396738
Vav/Phospholipase Cgamma2-mediated control of a neutrophil-dependent murine model of rheumatoid arthritisQ34419714
Regulation of phospholipase C isozymes by ras superfamily GTPasesQ34482971
Visualizing phosphoinositide signalling in single neurons gets a green lightQ35192520
Intracellular delivery of phosphoinositides and inositol phosphates using polyamine carriersQ35273278
A fluorogenic, small molecule reporter for mammalian phospholipase C isozymesQ35851757
Fluorescent phosphatidylinositol 4,5-bisphosphate derivatives with modified 6-hydroxy group as novel substrates for phospholipase C.Q36702204
Stimulation of phospholipase Cbeta by membrane interactions, interdomain movement, and G protein binding--how many ways can you activate an enzyme?Q36831338
Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancersQ37660073
Subtype-specific roles of phospholipase C-β via differential interactions with PDZ domain proteins.Q37805089
Mammalian phospholipase C.Q38058866
Membrane-binding properties of phospholipase C-beta1 and phospholipaseC-beta2: role of the C-terminus and effects of polyphosphoinositides, G-proteins and Ca2+.Q38341885
PLCG1 mutations in cutaneous T-cell lymphomasQ39027098
Photoactivatable and cell-membrane-permeable phosphatidylinositol 3,4,5-trisphosphate.Q39576038
Single cell analysis and temporal profiling of agonist-mediated inositol 1,4,5-trisphosphate, Ca2+, diacylglycerol, and protein kinase C signaling using fluorescent biosensors.Q40443128
Integrated molecular analysis of adult T cell leukemia/lymphoma.Q40466713
Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in miceQ42789241
Phospholipase C isozymes as effectors of Ras superfamily GTPasesQ43138796
Synthesis of fluorogenic substrates for continuous assay of phosphatidylinositol-specific phospholipase C.Q43582038
Comprehensive and uniform synthesis of all naturally occurring phosphorylated phosphatidylinositolsQ44296791
Fluorescent lipids: functional parts of fusogenic liposomes and tools for cell membrane labeling and visualization.Q51761678
CHELATOR: an improved method for computing metal ion concentrations in physiological solutions.Q52419808
Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cellsQ56990555
Catalytic domain of phosphoinositide-specific phospholipase C (PLC). Mutational analysis of residues within the active site and hydrophobic ridge of plcdelta1Q57648121
Analyzing phosphoinositides and their interacting proteinsQ57651388
Crystal structure of Rac1 bound to its effector phospholipase C-β2Q57945276
Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy TransferQ58423365
Synthesis of a new fluorogenic substrate for the continuous assay of mammalian phosphoinositide-specific phospholipase CQ77751735
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)1728-1735
P577publication date2017-12-20
P1433published inJournal of Biological ChemistryQ867727
P1476titleA membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymes
P478volume293

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cites work (P2860)
Q57074919Detection of Phospholipase C Activity in the Brain Homogenate from the Honeybee
Q92337963Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancer-associated mutations

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