Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice (scientific article published on January 2008)

Enhancement of macrophage survival and DNA synthesis by oxidized-low-density-lipoprotein (LDL)-derived lipids and by aggregates of lightly oxidized LDL

Q28360674

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

Q28509783

Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice

Q28585385

Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization

Q28589943

Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.

Q28590391

Inflammation in atherosclerosis

Q29547428

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

Q29547567

Nuclear factor-kappaB in cancer development and progression

Q29547879

BCL-2 family members and the mitochondria in apoptosis

Q29614427

Inositol phosphates and cell signalling

Q29615042

Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

Q29615236

The many faces of macrophage activation

Q29617449

The many roles of chemokines and chemokine receptors in inflammation

Q29618880

The biology of chemokines and their receptors

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Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent

Q30440410

Chemokines and chemokine receptors: biology and clinical relevance in inflammation and AIDS.

Q33540290

Phospholipase cbeta4 is specifically involved in climbing fiber synapse elimination in the developing cerebellum

Q33609245

Chemokines and atherosclerosis

Q33772440

MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B.

Q33844451

Functional plasticity of macrophages: reversible adaptation to changing microenvironments

Q33947557

Roles of phospholipid signaling in chemoattractant-induced responses

Q33996538

Chemokines, leukocytes, and atherosclerosis

Q34005747

Mechanisms of oxysterol-induced apoptosis

Q34372293

Oxidized LDL-induced injury and apoptosis in atherosclerosis. Potential roles for oxysterols

Q34423083

Lysophospholipid regulation of mononuclear phagocytes

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Progression of atheroma: a struggle between death and procreation

Q34858516

Oxidized low-density lipoprotein-induced apoptosis

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Deletion of the phosphoinositide 3-kinase p110gamma gene attenuates murine atherosclerosis

Q35781497

Modulation of atherogenesis by chemokines

Q35792119

Structural and functional characteristics of S1P receptors.

Q35839016

Cell surface receptors in lysophospholipid signaling

Q35844009

Physiological and pathological actions of sphingosine 1-phosphate.

Q35844027

Signaling mechanisms for regulation of chemotaxis

Q36027381

Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency

Q36248636

Roles of phospholipase C beta2 in chemoattractant-elicited responses

Q36298847

Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor

Q36380911

Growth factor withdrawal and apoptosis: the middle game

Q36423529

Phagocytosis in atherosclerosis: Molecular mechanisms and implications for plaque progression and stability.

Q36644805

Chemokines and atherosclerotic plaque progression: towards therapeutic targeting?

Q36789673

Phospholipase C beta 4 is involved in modulating the visual response in mice

Q37045727

Reduced macrophage apoptosis is associated with accelerated atherosclerosis in low-density lipoprotein receptor-null mice

Q37113551

Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate.

Q40280838

Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis

Q40316401

A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development

Q40391470

Mechanisms involved in apoptosis of human macrophages induced by lipopolysaccharide from Actinobacillus actinomycetemcomitans in the presence of cycloheximide

Q40574804

Minimally oxidized LDL offsets the apoptotic effects of extensively oxidized LDL and free cholesterol in macrophages.

Q45975661

Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis

Q46897070

Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.

Q52102307

Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions.

Q54610885

Oxidized low density lipoprotein inhibits macrophage apoptosis by blocking ceramide generation, thereby maintaining protein kinase B activation and Bcl-XL levels

Q73401195

Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice

Q77231603

Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice

Q77340592

Monocyte chemoattractant protein-1 accelerates atherosclerosis in apolipoprotein E-deficient mice

Q77862249

Oxysterols and atherosclerosis

Q77910747

Quantitative assay for mouse atherosclerosis in the aortic root

Q79330722

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

Q79370601

Impaired development of atherosclerosis in hyperlipidemic Ldlr-/- and ApoE-/- mice transplanted with Abcg1-/- bone marrow

Q80058470

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

atherosclerosis

Q12252367

apoptotic process

Q14599311

P304

page(s)

195-204

P577

publication date

2008-01-01

P1433

published in

Journal of Clinical Investigation

Q3186904

P1476

title

Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice

P478

volume

118

Reverse relations

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