| scholarly article | Q13442814 |
| P50 | author | Qisheng Zhang | Q84143071 |
| John Sondek | Q39895709 | ||
| P2093 | author name string | T Kendall Harden | |
| Matthew Barrett | |||
| Stephanie Hicks | |||
| Nicole Hajicek | |||
| Weigang Huang | |||
| P2860 | cites work | First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G | Q24615552 |
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| Quantification of Gi-mediated inhibition of adenylyl cyclase activity reveals that UDP is a potent agonist of the human P2Y14 receptor | Q37444485 | ||
| Potential treatment of cardiac hypertrophy and heart failure by inhibiting the sarcolemmal binding of phospholipase Cbeta1b | Q37738942 | ||
| Inositide-specific phospholipase c beta1 gene deletion in the progression of myelodysplastic syndrome to acute myeloid leukemia | Q38479148 | ||
| Anomalous inhibition of c-Met by the kinesin inhibitor aurintricarboxylic acid. | Q39576693 | ||
| The phosphoinositide-specific phospholipase C inhibitor U73122 (1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione) spontaneously forms conjugates with common components of cell culture medium. | Q40150786 | ||
| A role for phospholipase C-gamma-mediated signaling in tumor cell invasion | Q40931396 | ||
| A detergent-based assay for the detection of promiscuous inhibitors | Q42007896 | ||
| The PI-PLC inhibitor U-73122 is a potent inhibitor of the SERCA pump in smooth muscle. | Q42427186 | ||
| Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development | Q42471916 | ||
| Characterization of the major phosphoinositide-specific phospholipase C of human amnion | Q42474365 | ||
| Synthesis and evaluation of fluorogenic substrates for phospholipase D and phospholipase C | Q42528674 | ||
| Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice | Q42789241 | ||
| Phospholipase C beta 1 deficiency is associated with early-onset epileptic encephalopathy | Q42910095 | ||
| U73122, an aminosteroid phospholipase C inhibitor, is a potent inhibitor of cardiac phospholipase D by a PIP2-dependent mechanism | Q43152368 | ||
| Synthesis of fluorogenic substrates for continuous assay of phosphatidylinositol-specific phospholipase C. | Q43582038 | ||
| Development of a high-throughput assay for two inositol-specific phospholipase Cs using a scintillation proximity format | Q44847995 | ||
| Aurin tricarboxylic acid inhibits adhesion of platelets to subendothelium | Q45099599 | ||
| The aminosteroid phospholipase C antagonist U-73122 (1-[6-[[17-beta-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione) potently inhibits human 5-lipoxygenase in vivo and in vitro | Q45246313 | ||
| Phospholipase Cepsilon promotes intestinal tumorigenesis of Apc(Min/+) mice through augmentation of inflammation and angiogenesis. | Q46003371 | ||
| Quantification of isozyme-specific activation of phospholipase C-beta2 by Rac GTPases and phospholipase C-epsilon by Rho GTPases in an intact cell assay system | Q46940009 | ||
| A highly sensitive adenylate cyclase assay | Q47871494 | ||
| A high-throughput screen for aggregation-based inhibition in a large compound library | Q48080055 | ||
| Hydrolysis of short acyl chain inositol lipids by phospholipase C-delta 1. | Q48344846 | ||
| Phosphoinositide-phospholipase C beta1 mono-allelic deletion is associated with myelodysplastic syndromes evolution into acute myeloid leukemia. | Q54501204 | ||
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| Phospholipase C-β2 promotes mitosis and migration of human breast cancer-derived cells | Q62017164 | ||
| U73122 affects the equilibria between the phosphoinositides as well as phospholipase C activity in unstimulated and thrombin-stimulated human and rabbit platelets | Q70474729 | ||
| U-73122, an aminosteroid phospholipase C inhibitor, may also block Ca2+ influx through phospholipase C-independent mechanism in neutrophil activation | Q71341215 | ||
| Evidence obtained using single hepatocytes for inhibition by the phospholipase C inhibitor U73122 of store-operated Ca2+ inflow | Q72269520 | ||
| Differential modification of the interaction of cardiac muscarinic cholinergic and beta-adrenergic receptors with a guanine nucleotide binding component(s) | Q72945531 | ||
| Fluorescent inhibitors for the qualitative and quantitative analysis of lipolytic enzymes | Q73239166 | ||
| Aurintricarboxylic acid promotes survival and regeneration of axotomised retinal ganglion cells in vivo | Q73503186 | ||
| Evidence for separate effects of U73122 on phospholipase C and calcium channels in human platelets | Q77596611 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 5840-5848 | |
| P577 | publication date | 2013-01-07 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Small molecule inhibitors of phospholipase C from a novel high-throughput screen | |
| P478 | volume | 288 |
| Q28551491 | Charge Shielding of PIP2 by Cations Regulates Enzyme Activity of Phospholipase C |
| Q38179801 | Chemical modulation of glycerolipid signaling and metabolic pathways |
| Q90634271 | Fgd5 is a Rac1-specific Rho GEF that is selectively inhibited by aurintricarboxylic acid |
| Q46351354 | Insights into the inhibitory mechanism of triazole-based small molecules on phosphatidylinositol-4,5-bisphosphate binding pleckstrin homology domain |
| Q41815540 | Peptide microarray profiling identifies phospholipase C gamma 1 (PLC-γ1) as a potential target for t(8;21) AML. |
| Q36784632 | Phosphoinositide-3-Kinase Is the Primary Mediator of Phosphoinositide-Dependent Inhibition in Mammalian Olfactory Receptor Neurons |
| Q27012953 | Phosphoinositides: tiny lipids with giant impact on cell regulation |
| Q27345107 | Phospholipase cε, an effector of ras and rap small GTPases, is required for airway inflammatory response in a mouse model of bronchial asthma |
| Q37193142 | Structural insights into phospholipase C-β function. |
| Q47250401 | The inositol pyrophosphate pathway in health and diseases |
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