review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1111/BRV.12392 |
P8608 | Fatcat ID | release_pjd7hdvruzeclgugpzcwivvrbq |
P932 | PMC publication ID | 6383672 |
P698 | PubMed publication ID | 29282838 |
P2093 | author name string | Anutosh Chakraborty | |
P2860 | cites work | Multiple modes of cytoplasmic dynein regulation | Q83531140 |
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Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates | Q22010877 | ||
Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. An expanding Nudt family | Q22253958 | ||
Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cells | Q24291206 | ||
Identification and characterization of a novel inositol hexakisphosphate kinase | Q24291558 | ||
A conserved family of enzymes that phosphorylate inositol hexakisphosphate | Q24301881 | ||
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach | Q24321897 | ||
Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress | Q24337620 | ||
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Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA | Q24568308 | ||
A quantitative atlas of mitotic phosphorylation | Q24646817 | ||
Effect of inositol hexakisphosphate kinase 2 on transforming growth factor beta-activated kinase 1 and NF-kappaB activation | Q24670467 | ||
Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics | Q24672792 | ||
Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron | Q26269873 | ||
The emerging roles of inositol pyrophosphates in eukaryotic cell physiology | Q26786441 | ||
Insulin receptor signaling in normal and insulin-resistant states | Q26823171 | ||
The enzymes of human diphosphoinositol polyphosphate metabolism | Q26851038 | ||
Signaling through C2 domains: more than one lipid target | Q27014032 | ||
Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding | Q27675827 | ||
IP6K structure and the molecular determinants of catalytic specificity in an inositol phosphate kinase family | Q27684442 | ||
The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis | Q27929981 | ||
Identification of an evolutionarily conserved family of inorganic polyphosphate endopolyphosphatases | Q27932475 | ||
Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases | Q27939197 | ||
Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases | Q28116072 | ||
Back in the water: the return of the inositol phosphates | Q28186774 | ||
Genetic rationale for microheterogeneity of human diphosphoinositol polyphosphate phosphohydrolase type 2 | Q28190925 | ||
Evolution of protein kinase signaling from yeast to man | Q28205635 | ||
Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate | Q28205958 | ||
Inorganic polyphosphate: essential for growth and survival | Q28240351 | ||
The IHPK1 gene is disrupted at the 3p21.31 breakpoint of t(3;9) in a family with type 2 diabetes mellitus | Q28268909 | ||
The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging | Q28276378 | ||
Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain | Q28304043 | ||
The blood-testis barrier and its implications for male contraception | Q28395237 | ||
Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases | Q28510332 | ||
Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response | Q28540195 | ||
GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase | Q28571302 | ||
Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains | Q28609779 | ||
Inositol pyrophosphates: why so many phosphates? | Q28652347 | ||
IP3 3-kinase opposes NGF driven neurite outgrowth | Q28731851 | ||
The versatility and universality of calcium signalling | Q29547402 | ||
Histone methylation in transcriptional control | Q29616553 | ||
Mechanisms of specificity in protein phosphorylation | Q29617541 | ||
Linking DNA methylation and histone modification: patterns and paradigms | Q29617801 | ||
Inositol hexakisphosphate kinase-2 acts as an effector of the vertebrate Hedgehog pathway | Q30497487 | ||
Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo | Q33281051 | ||
How does synaptotagmin trigger neurotransmitter release? | Q33345212 | ||
Inhibition of the ER Ca2+ pump forces multidrug-resistant cells deficient in Bak and Bax into necrosis | Q33516101 | ||
Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice | Q37020337 | ||
Cellular energetic status supervises the synthesis of bis-diphosphoinositol tetrakisphosphate independently of AMP-activated protein kinase | Q37077554 | ||
Inositol pyrophosphates inhibit synaptotagmin-dependent exocytosis. | Q37126685 | ||
Arsenic-based antineoplastic drugs and their mechanisms of action | Q37145891 | ||
Inositol pyrophosphates and their unique metabolic complexity: analysis by gel electrophoresis | Q37186675 | ||
Inositol Hexakisphosphate Kinase 3 Regulates Metabolism and Lifespan in Mice | Q37219919 | ||
Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis | Q37233462 | ||
Diphosphoinositol polyphosphates: metabolic messengers? | Q37268113 | ||
Inositol pyrophosphates regulate JMJD2C-dependent histone demethylation. | Q37340761 | ||
Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport | Q37394301 | ||
Inositol polyphosphates intersect with signaling and metabolic networks via two distinct mechanisms. | Q37398176 | ||
Understanding inositol pyrophosphate metabolism and function: kinetic characterization of the DIPPs | Q37416185 | ||
Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release | Q37482212 | ||
Inositol pyrophosphates: structure, enzymology and function | Q37588509 | ||
PPIP5K1 modulates ligand competition between diphosphoinositol polyphosphates and PtdIns(3,4,5)P3 for polyphosphoinositide-binding domains | Q37596231 | ||
Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor | Q37635615 | ||
Receptor-dependent compartmentalization of PPIP5K1, a kinase with a cryptic polyphosphoinositide binding domain | Q37657049 | ||
Detecting UV-lesions in the genome: The modular CRL4 ubiquitin ligase does it best! | Q37873069 | ||
Protein phosphorylation from the perspective of systems biology. | Q37961317 | ||
Cell signalling by inositol pyrophosphates | Q37989043 | ||
Synthesis and biological actions of diphosphoinositol phosphates (inositol pyrophosphates), regulators of cell homeostasis | Q38040272 | ||
Inositol pyrophosphates: between signalling and metabolism | Q38110945 | ||
Metabolism and function of myo-inositol and inositol phospholipids | Q38164564 | ||
Akt/PKB activation and insulin signaling: a novel insulin signaling pathway in the treatment of type 2 diabetes | Q38194549 | ||
Molecular control of PtdIns(3,4,5)P3 signaling in neutrophils | Q38313393 | ||
IP6K1 Reduces Mesenchymal Stem/Stromal Cell Fitness and Potentiates High Fat Diet-Induced Skeletal Involution. | Q38430822 | ||
Global IP6K1 deletion enhances temperature modulated energy expenditure which reduces carbohydrate and fat induced weight gain | Q38433610 | ||
TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway | Q38435784 | ||
Inositol hexakisphosphate kinase-1 interacts with perilipin1 to modulate lipolysis | Q38437282 | ||
Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase | Q38522112 | ||
Regulation of brown fat by AMP-activated protein kinase | Q38566113 | ||
Towards pharmacological intervention in inositol pyrophosphate signalling | Q38728101 | ||
Chemical tools for interrogating inositol pyrophosphate structure and function. | Q38837404 | ||
AKT in cancer: new molecular insights and advances in drug development | Q38846044 | ||
Unambiguous Identification of Serine and Threonine Pyrophosphorylation Using Neutral-Loss-Triggered Electron-Transfer/Higher-Energy Collision Dissociation. | Q38951747 | ||
Inositol phospholipids and cell surface receptor function | Q56091374 | ||
The detection, purification, structural characterization, and metabolism of diphosphoinositol pentakisphosphate(s) and bisdiphosphoinositol tetrakisphosphate(s) | Q70578917 | ||
Turnover of inositol polyphosphate pyrophosphates in pancreatoma cells | Q72952296 | ||
The diversity and possible functions of the inositol polyphosphate 5-phosphatases | Q77631387 | ||
Phosphate transfer from inositol pyrophosphates InsP5PP and InsP4(PP)2: a semi-empirical investigation | Q79256314 | ||
Crystal structure of inositol phosphate multikinase 2 and implications for substrate specificity | Q79271161 | ||
Extraction and analysis of soluble inositol polyphosphates from yeast | Q80093282 | ||
Asp1 from Schizosaccharomyces pombe binds a [2Fe-2S](2+) cluster which inhibits inositol pyrophosphate 1-phosphatase activity | Q36270671 | ||
Inositol pyrophosphates: metabolism and signaling | Q36375032 | ||
Low-grade serous carcinomas of the ovary contain very few point mutations | Q36415602 | ||
HSP90 regulates cell survival via inositol hexakisphosphate kinase-2. | Q36446083 | ||
IP6K2 is a client for HSP90 and a target for cancer therapeutics development | Q36446267 | ||
Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis | Q36497226 | ||
Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair | Q36579532 | ||
Pleckstrin homology (PH) domains and phosphoinositides | Q36711258 | ||
Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence | Q36754718 | ||
Regulation of UV-induced DNA damage response by ubiquitylation | Q36760894 | ||
Nudt3 is an mRNA decapping enzyme that modulates cell migration | Q36812733 | ||
Cigarette smoke (CS) and nicotine delay neutrophil spontaneous death via suppressing production of diphosphoinositol pentakisphosphate | Q36835730 | ||
Inositol pyrophosphates as mammalian cell signals | Q36886772 | ||
Inositol Hexakisphosphate Kinase 1 (IP6K1) Regulates Inositol Synthesis in Mammalian Cells | Q36898165 | ||
Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2 | Q33570316 | ||
The Obesity-Linked Gene Nudt3 Drosophila Homolog Aps Is Associated With Insulin Signaling | Q33631545 | ||
Role of synaptotagmin, a Ca2+ and inositol polyphosphate binding protein, in neurotransmitter release and neurite outgrowth | Q33652647 | ||
Inositol pyrophosphates mediate the effects of aging on bone marrow mesenchymal stem cells by inhibiting Akt signaling | Q33746634 | ||
Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases | Q33836143 | ||
Turnover of bis-diphosphoinositol tetrakisphosphate in a smooth muscle cell line is regulated by beta2-adrenergic receptors through a cAMP-mediated, A-kinase-independent mechanism | Q33888504 | ||
Zinc release from thapsigargin/IP3-sensitive stores in cultured cortical neurons | Q33964708 | ||
An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase. | Q34137530 | ||
Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate | Q34264314 | ||
Cancer Inhibition by Inositol Hexaphosphate (IP6) and Inositol: From Laboratory to Clinic | Q34275641 | ||
Small molecule inhibitors of phospholipase C from a novel high-throughput screen. | Q34321407 | ||
Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death | Q34366232 | ||
Phosphorylation of proteins by inositol pyrophosphates | Q34377316 | ||
Inositol pyrophosphates regulate endocytic trafficking | Q34392736 | ||
p53-mediated apoptosis requires inositol hexakisphosphate kinase-2 | Q34397020 | ||
The Nudix hydrolase superfamily | Q34479614 | ||
Identification of a functional nuclear translocation sequence in hPPIP5K2. | Q34481151 | ||
Inositol phospholipids and cell surface receptor function | Q34486299 | ||
Progressive but previously untreated CLL patients with greater array CGH complexity exhibit a less durable response to chemoimmunotherapy | Q34519192 | ||
Inositol hexakisphosphate kinase-1 mediates assembly/disassembly of the CRL4-signalosome complex to regulate DNA repair and cell death | Q34526364 | ||
How versatile are inositol phosphate kinases? | Q34542639 | ||
Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2. | Q34573044 | ||
Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event | Q34688142 | ||
New concepts in chronic obstructive pulmonary disease | Q34930970 | ||
Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer | Q35034550 | ||
Understanding the relationship between DNA methylation and histone lysine methylation | Q35046027 | ||
Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis | Q35056776 | ||
Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1 | Q35090038 | ||
Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma | Q35208535 | ||
A novel method for the purification of inositol phosphates from biological samples reveals that no phytate is present in human plasma or urine | Q35318869 | ||
Fungal Inositol Pyrophosphate IP7 Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity | Q35676308 | ||
Oncostatin M (OSM) protects against cardiac ischaemia/reperfusion injury in diabetic mice by regulating apoptosis, mitochondrial biogenesis and insulin sensitivity | Q35695541 | ||
Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo | Q35913992 | ||
Inositol Pyrophosphate Profiling of Two HCT116 Cell Lines Uncovers Variation in InsP8 Levels. | Q36176216 | ||
The significance of the 1-kinase/1-phosphatase activities of the PPIP5K family | Q38989731 | ||
Intimate connections: Inositol pyrophosphates at the interface of metabolic regulation and cell signaling. | Q39329205 | ||
An Investigation of Phytin | Q39480954 | ||
Characterization of a selective inhibitor of inositol hexakisphosphate kinases: use in defining biological roles and metabolic relationships of inositol pyrophosphates. | Q39885162 | ||
Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic beta cells | Q40046011 | ||
Signal transduction during environmental stress: InsP8 operates within highly restricted contexts | Q40413479 | ||
Apo2L/TRAIL induction and nuclear translocation of inositol hexakisphosphate kinase 2 during IFN-beta-induced apoptosis in ovarian carcinoma. | Q40474530 | ||
Genome-wide DNA methylation in saliva and body size of adolescent girls. | Q40495062 | ||
Protocols for regulation and study of diphosphoinositol polyphosphates. | Q40519725 | ||
Integrated genomic and proteomic analyses of gene expression in Mammalian cells | Q40538549 | ||
Ectopic expression of murine diphosphoinositol polyphosphate phosphohydrolase 1 attenuates signaling through the ERK1/2 pathway | Q40542484 | ||
Complex changes in cellular inositol phosphate complement accompany transit through the cell cycle | Q40583917 | ||
Inositol pyrophosphates are required for DNA hyperrecombination in protein kinase c1 mutant yeast | Q40750059 | ||
Dependence of energy metabolism on the density of cells in culture. | Q41024343 | ||
Establishing the stability and reversibility of protein pyrophosphorylation with synthetic peptides | Q41499357 | ||
Inositol pyrophosphates regulate cell growth and the environmental stress response by activating the HDAC Rpd3L. | Q41512865 | ||
The interconversion of inositol 1,3,4,5,6-pentakisphosphate and inositol tetrakisphosphates in AR4-2J cells | Q41594669 | ||
Adipocyte-specific deletion of Ip6k1 reduces diet-induced obesity by enhancing AMPK-mediated thermogenesis | Q41679412 | ||
myo-inositol pentakisphosphates. Structure, biological occurrence and phosphorylation to myo-inositol hexakisphosphate | Q41687573 | ||
The inositol phosphates in WRK1 rat mammary tumour cells | Q41810643 | ||
Inositol hexakisphosphate kinases induce cell death in Huntington disease | Q41820993 | ||
Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling | Q41830941 | ||
Insulin signaling: inositol phosphates get into the Akt. | Q41841387 | ||
Inositol Hexakisphosphate Kinase-3 Regulates the Morphology and Synapse Formation of Cerebellar Purkinje Cells via Spectrin/Adducin. | Q41846418 | ||
Modulation of Epidermal Growth Factor Stimulated ERK Phosphorylation and Cell Motility by Inositol Trisphosphate Kinase. | Q41883939 | ||
Structures of diphospho-myo-inositol pentakisphosphate and bisdiphospho-myo-inositol tetrakisphosphate from Dictyostelium resolved by NMR analysis | Q41982271 | ||
Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain | Q42053859 | ||
Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase. | Q42318137 | ||
Inositol diphosphate signaling regulates telomere length | Q42641267 | ||
Turnover of inositol pentakisphosphates, inositol hexakisphosphate and diphosphoinositol polyphosphates in primary cultured hepatocytes | Q42745423 | ||
Rat brain inositol 1,4,5-trisphosphate 3-kinase. Ca2+-sensitivity, purification and antibody production | Q42794241 | ||
Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates | Q42971039 | ||
Synthesis and characterization of non-hydrolysable diphosphoinositol polyphosphate second messengers. | Q43074238 | ||
Inositol pyrophosphates regulate RNA polymerase I-mediated rRNA transcription in Saccharomyces cerevisiae | Q43143870 | ||
The SIN1-PH Domain Connects mTORC2 to PI3K. | Q43183422 | ||
Inositol hexakisphosphate kinase-1 regulates behavioral responses via GSK3 signaling pathways | Q44273064 | ||
Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions | Q44587829 | ||
Accumulation of [3H]-inositol into inositol polyphosphates during development of Dictyostelium | Q44610185 | ||
KO of 5-InsP7 kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotype. | Q44876576 | ||
Signaling by higher inositol polyphosphates. Synthesis of bisdiphosphoinositol tetrakisphosphate ("InsP8") is selectively activated by hyperosmotic stress | Q45021750 | ||
Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups | Q45345663 | ||
Inositol pyrophosphates modulate hydrogen peroxide signalling. | Q45926680 | ||
Plc1p, Arg82p, and Kcs1p, enzymes involved in inositol pyrophosphate synthesis, are essential for phosphate regulation and polyphosphate accumulation in Saccharomyces cerevisiae | Q46468800 | ||
The regulation of membrane to cytosol partitioning of signalling proteins by phosphoinositides and their soluble headgroups | Q46771498 | ||
Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels | Q46774343 | ||
Protein kinase- and lipase inhibitors of inositide metabolism deplete IP7 indirectly in pancreatic β-cells: Off-target effects on cellular bioenergetics and direct effects on IP6K activity | Q47637691 | ||
Development of a homogenous high-throughput assay for inositol hexakisphosphate kinase 1 activity | Q47944803 | ||
IP6K1 is essential for chromatoid body formation and temporal regulation of Tnp2 and Prm2 expression in mouse spermatids | Q48028376 | ||
Selective inhibition of inositol hexakisphosphate kinases (IP6Ks) enhances mesenchymal stem cell engraftment and improves therapeutic efficacy for myocardial infarction. | Q50456025 | ||
Inositol Hexakisphosphate Kinase 2 is a Presymptomatic Biomarker for Amyotrophic Lateral Sclerosis. | Q51055246 | ||
Contribution of polymorphic variation of inositol hexakisphosphate kinase 3 (IP6K3) gene promoter to the susceptibility to late onset Alzheimer's disease. | Q51282160 | ||
Influence of inositol pyrophosphates on cellular energy dynamics. | Q51847806 | ||
Inositol Hexakisphosphate Kinase 2 Promotes Cell Death in Cells with Cytoplasmic TDP-43 Aggregation. | Q52911856 | ||
NUDT3 rs206936 is associated with body mass index in obese Japanese women. | Q53108028 | ||
p53 Transgenic mice are highly susceptible to 4-nitroquinoline-1-oxide-induced oral cancer. | Q53617705 | ||
A Fluorescent Sensor and Gel Stain for Detection of Pyrophosphorylated Proteins. | Q53659145 | ||
Discovery of InsP6-kinases as InsP6-dephosphorylating enzymes provides a new mechanism of cytosolic InsP6 degradation driven by the cellular ATP/ADP ratio. | Q54349708 | ||
PPIP5K1 interacts with the exocyst complex through a C-terminal intrinsically disordered domain and regulates cell motility. | Q55031073 | ||
P433 | issue | 2 | |
P304 | page(s) | 1203-1227 | |
P577 | publication date | 2017-12-27 | |
P1433 | published in | Biological Reviews | Q2500948 |
P1476 | title | The inositol pyrophosphate pathway in health and diseases | |
P478 | volume | 93 |