Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics

scientific article

Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.ONC.1205265
P932PMC publication ID2043497
P698PubMed publication ID11896621

P50authorMamta Chawla-SarkarQ61771491
P2093author name stringDhananjaya V Kalvakolanu
Jiadi Hu
Bendi Gong
Joseph A Bauer
Daniel J Lindner
Alex Almasan
Bei H Morrison
Aylin M Ozdemir
Ronald W Grane
P2860cites workSynthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinasesQ22010845
Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cellsQ24291206
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Induction of apoptosis and inhibition of cell growth are independent responses to interferon-alpha in hematopoietic cell linesQ28305124
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2Q28609079
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repairQ28646559
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitorsQ29547463
New colorimetric cytotoxicity assay for anticancer-drug screeningQ29615418
Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo.Q34086453
Inositol hexakisphosphate binds to clathrin assembly protein 3 (AP-3/AP180) and inhibits clathrin cage assembly in vitroQ34315447
Inhibition of clathrin assembly by high affinity binding of specific inositol polyphosphates to the synapse-specific clathrin assembly protein AP-3.Q38299578
Transcriptional activation of TRADD mediates p53-independent radiation-induced apoptosis of glioma cellsQ40796980
Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: correlation with TRAIL/Apo2L induction in melanoma cell lines.Q40798570
Effect of ultraviolet light, methyl methanesulfonate and ionizing radiation on the genotoxic response and apoptosis of mouse fibroblasts lacking c-Fos, p53 or bothQ40810117
Transfer of human chromosome 3 to an ovarian carcinoma cell line identifies three regions on 3p involved in ovarian cancerQ41415869
Abnormal structure and expression of the p53 gene in human ovarian carcinoma cell lines.Q41609796
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.Q41747264
Structural identification of the myo-inositol 1,4,5-trisphosphate-binding domain in rat brain inositol 1,4,5-trisphosphate 3-kinaseQ42159660
Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide bindingQ42667054
Irradiation of mitochondria initiates apoptosis in a cell free systemQ43583342
Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated geneQ43624125
Inositol hexakisphosphate receptor identified as the clathrin assembly protein AP-2Q43913945
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancerQ48084125
Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells.Q54008325
Thymocyte apoptosis induced by p53-dependent and independent pathways.Q54242475
Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignanciesQ56421857
Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancerQ59079930
Clinical usefulness of thyroid-stimulating antibody measurement using Chinese hamster ovary cells expressing human thyrotropin receptorsQ71937889
Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionizing radiation in leukemic cellsQ73144184
Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosisQ73540307
Binding kinetics and ligand specificity for the interactions of the C2B domain of synaptogmin II with inositol polyphosphates and phosphoinositidesQ74138378
Induction of multiple programmed cell death pathways by IFN-beta in human non-small-cell lung cancer cell linesQ74520572
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectovarian carcinomaQ18556145
P304page(s)1882-9
1882-1889
P577publication date2002-03-01
2002-03-14
P1433published inOncogeneQ1568657
P1476titleInositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics
P478volume21

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cites work (P2860)
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Q24670467Effect of inositol hexakisphosphate kinase 2 on transforming growth factor beta-activated kinase 1 and NF-kappaB activation
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