Inositol hexakisphosphate binds to clathrin assembly protein 3 (AP-3/AP180) and inhibits clathrin cage assembly in vitro

scientific article

Inositol hexakisphosphate binds to clathrin assembly protein 3 (AP-3/AP180) and inhibits clathrin cage assembly in vitro is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.270.1.214
P698PubMed publication ID7814377

P2093author name stringMajerus PW
Ungewickell E
Norris FA
P2860cites workLight-chain-independent binding of adaptors, AP180, and auxilin to clathrinQ48654749
Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites.Q52516078
Basic local alignment search toolQ25938991
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sortingQ27940116
Establishing homologies in protein sequencesQ29618225
Endocytosis and signals for internalizationQ36457812
Inositol polyphosphate receptor and clathrin assembly protein AP-2 are related proteins that form potassium-selective ion channels in planar lipid bilayersQ37216975
Inositol 1,3,4,5-tetrakisphosphate and inositol hexakisphosphate receptor proteins: isolation and characterization from rat brainQ37478548
Clathrin-coated vesiclesQ38375090
100-kD coated vesicle proteins: molecular heterogeneity and intracellular distribution studied with monoclonal antibodiesQ41514832
Studies on NG-methylarginine derivatives in myelin basic protein from developing and mutant mouse brainQ42136647
Inositol hexakisphosphate receptor identified as the clathrin assembly protein AP-2Q43913945
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)214-217
P577publication date1995-01-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleInositol hexakisphosphate binds to clathrin assembly protein 3 (AP-3/AP180) and inhibits clathrin cage assembly in vitro
P478volume270

Reverse relations

cites work (P2860)
Q38353871A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway
Q27630407A novel all helix fold of the AP180 amino-terminal domain for phosphoinositide binding and clathrin assembly in synaptic vesicle endocytosis
Q28565411A presynaptic inositol-5-phosphatase
Q41283307A role for phosphatidylinositol transfer protein in secretory vesicle formation
Q40495561A role for rat inositol polyphosphate kinases rIPK2 and rIPK1 in inositol pentakisphosphate and inositol hexakisphosphate production in rat-1 cells
Q47907518A role for the clathrin assembly domain of AP180 in synaptic vesicle endocytosis.
Q28578069AP180 and AP-2 interact directly in a complex that cooperatively assembles clathrin
Q40474530Apo2L/TRAIL induction and nuclear translocation of inositol hexakisphosphate kinase 2 during IFN-beta-induced apoptosis in ovarian carcinoma.
Q33940944Assessing the omnipotence of inositol hexakisphosphate
Q28186774Back in the water: the return of the inositol phosphates
Q48337977Bridging the GAP in inositol 1,3,4,5-tetrakisphosphate signalling.
Q22010470Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic
Q28513174Developmentally regulated alternative splicing in a novel synaptojanin
Q33854102Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression
Q30176794Dynamin, endocytosis and intracellular signalling (review).
Q44251927Effects of 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one on synaptic vesicle cycling at the frog neuromuscular junction.
Q34897542Endocytic adaptors--social networking at the plasma membrane
Q27939888Epsins: adaptors in endocytosis?
Q48569610Expression and subcellular localization of p42IP4/centaurin-alpha, a brain-specific, high-affinity receptor for inositol 1,3,4,5-tetrakisphosphate and phosphatidylinositol 3,4,5-trisphosphate in rat brain
Q36325794G protein-coupled receptor/arrestin3 modulation of the endocytic machinery
Q28571302GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase
Q24291558Identification and characterization of a novel inositol hexakisphosphate kinase
Q48682592Inhibition of phospholipase D by clathrin assembly protein 3 (AP3).
Q34088988Inositol 1,3,4-trisphosphate 5/6-kinase is a protein kinase that phosphorylates the transcription factors c-Jun and ATF-2.
Q91600423Inositol Pyrophosphate Metabolism Regulates Presynaptic Vesicle Cycling at Central Synapses
Q28203745Inositol derivatives modulate spontaneous transmitter release at the frog neuromuscular junction
Q41830941Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling
Q24672792Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics
Q43866602Inositol hexakisphosphate-mediated regulation of glutamate receptors in rat brain sections
Q41429704Inositol phosphates and inositol phospholipids: how big is the iceberg?
Q34981485Inositol phosphates in foods
Q77393282Inositol polyphosphates regulate the membrane interactions of the endosomal p100, G-protein-related protein
Q44587829Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions
Q34392736Inositol pyrophosphates regulate endocytic trafficking
Q37588509Inositol pyrophosphates: structure, enzymology and function
Q42981936Isolation of InsP4 and InsP6 binding proteins from human platelets: InsP4 promotes Ca2+ efflux from inside-out plasma membrane vesicles containing 104 kDa GAP1IP4BP protein
Q36256904Mechanism of clathrin basket dissociation: separate functions of protein domains of the DnaJ homologue auxilin
Q22009077Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19
Q48881395Myelin proteolipid protein (PLP), but not DM-20, is an inositol hexakisphosphate-binding protein
Q38319928Nitric oxide regulates interleukin-8 gene expression in activated endothelium by inhibiting NF-kappaB binding to DNA: effects on endothelial function
Q33966652Opposing effects of a tyrosine-based sorting motif and a PDZ-binding motif regulate human T-lymphotropic virus type 1 envelope trafficking
Q27932146Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis
Q35504084Phosphatases: the new brakes for cancer development?
Q34268347Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer
Q34490302Phytic Acid as a Potential Treatment for Alzheimer's Pathology: Evidence from Animal and in vitro Models
Q46468800Plc1p, Arg82p, and Kcs1p, enzymes involved in inositol pyrophosphate synthesis, are essential for phosphate regulation and polyphosphate accumulation in Saccharomyces cerevisiae
Q37635615Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor
Q35854151Rac signaling in breast cancer: a tale of GEFs and GAPs.
Q51377286Reconstitution of clathrin-coated bud and vesicle formation with minimal components.
Q28591322Regulation of AP-3 function by inositides. Identification of phosphatidylinositol 3,4,5-trisphosphate as a potent ligand
Q50337340Role of auxilin in uncoating clathrin-coated vesicles
Q41734067Sorting out adaptors
Q44419037Stimulation of L-type Ca2+ channels by inositol pentakis- and hexakisphosphates in rat vascular smooth muscle cells
Q28293468Synaptic vesicle size and number are regulated by a clathrin adaptor protein required for endocytosis
Q38796988Synthesis of an inositol hexakisphosphate (IP6) affinity probe to study the interactome from a colon cancer cell line.
Q35191034The monomeric clathrin assembly protein, AP180, regulates contractile vacuole size in Dictyostelium discoideum
Q34365911The pathway for the production of inositol hexakisphosphate in human cells
Q24300393The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase
Q24314354The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family
Q77631236The versatility of inositol phosphates as cellular signals
Q24647131UNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesicles
Q28909703Unusual structural organization of the endocytic proteins AP180 and epsin 1
Q43001094myo-Inositol hexakisphosphate is a major component of an extracellular structure in the parasitic cestode Echinococcus granulosus

Search more.