| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Mark P Thomas | Q96099375 |
| Barry Potter | Q56559893 | ||
| P2860 | cites work | Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases | Q21284394 |
| Towards a proteome-scale map of the human protein–protein interaction network | Q21735930 | ||
| A probability-based approach for high-throughput protein phosphorylation analysis and site localization | Q21735934 | ||
| The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein | Q22010421 | ||
| Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases | Q22010845 | ||
| Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates | Q22010877 | ||
| Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. An expanding Nudt family | Q22253958 | ||
| Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cells | Q24291206 | ||
| Identification and characterization of a novel inositol hexakisphosphate kinase | Q24291558 | ||
| MgF(3)(-) as a transition state analog of phosphoryl transfer | Q24292944 | ||
| Toward an understanding of the protein interaction network of the human liver | Q24292988 | ||
| Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin | Q24295284 | ||
| Next-generation sequencing to generate interactome datasets | Q24300269 | ||
| The detection, purification, structural characterization, and metabolism of diphosphoinositol pentakisphosphate(s) and bisdiphosphoinositol tetrakisphosphate(s) | Q70578917 | ||
| Turnover of inositol polyphosphate pyrophosphates in pancreatoma cells | Q72952296 | ||
| Diphospho-myo-inositol phosphates in Dictyostelium and Polysphondylium: identification of a new bisdiphospho-myo-inositol tetrakisphosphate | Q74582960 | ||
| Crystal structure of inositol phosphate multikinase 2 and implications for substrate specificity | Q79271161 | ||
| Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates | Q42971039 | ||
| Diphospho-myo-inositol phosphates from Dictyostelium identified as D-6-diphospho-myo-inositol pentakisphosphate and D-5,6-bisdiphospho-myo-inositol tetrakisphosphate | Q42985531 | ||
| Inositol hexakisphosphate kinase-1 regulates behavioral responses via GSK3 signaling pathways | Q44273064 | ||
| Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions | Q44587829 | ||
| Signaling by higher inositol polyphosphates. Synthesis of bisdiphosphoinositol tetrakisphosphate ("InsP8") is selectively activated by hyperosmotic stress | Q45021750 | ||
| Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups | Q45345663 | ||
| When worlds collide: inositol pyrophosphates and phosphoinositides intersect at the plasma membrane | Q45538704 | ||
| Inositol pyrophosphates modulate hydrogen peroxide signalling. | Q45926680 | ||
| Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels | Q46774343 | ||
| Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra | Q46959590 | ||
| Inositol polyphosphates, diphosphoinositol polyphosphates and phosphatidylinositol polyphosphate lipids: structure, synthesis, and development of probes for studying biological activity | Q37780461 | ||
| The signaling role of inositol hexakisphosphate kinases (IP6Ks) | Q37805097 | ||
| Compartmentation of membrane processes and nucleotide dynamics in diffusion-restricted cardiac cell microenvironment | Q37894285 | ||
| The mammalian circadian timing system: synchronization of peripheral clocks | Q37969676 | ||
| The SOCS box-adapting proteins for ubiquitination and proteasomal degradation | Q37987879 | ||
| Defining signal transduction by inositol phosphates | Q37989042 | ||
| Inositol 1,4,5-trisphosphate and its receptors. | Q37997677 | ||
| Synthesis and biological actions of diphosphoinositol phosphates (inositol pyrophosphates), regulators of cell homeostasis | Q38040272 | ||
| Toward a systems-level understanding of the Hedgehog signaling pathway: defining the complex, robust, and fragile | Q38051564 | ||
| Inositol pyrophosphates: between signalling and metabolism | Q38110945 | ||
| Inhibition of clathrin assembly by high affinity binding of specific inositol polyphosphates to the synapse-specific clathrin assembly protein AP-3. | Q38299578 | ||
| SnapShot: Inositol phosphates | Q38429481 | ||
| The secret life of kinases: functions beyond catalysis | Q39077751 | ||
| Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions | Q39811057 | ||
| Characterization of a selective inhibitor of inositol hexakisphosphate kinases: use in defining biological roles and metabolic relationships of inositol pyrophosphates. | Q39885162 | ||
| Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic beta cells | Q40046011 | ||
| A non-catalytic role of choline kinase alpha is important in promoting cancer cell survival | Q40289536 | ||
| Apo2L/TRAIL induction and nuclear translocation of inositol hexakisphosphate kinase 2 during IFN-beta-induced apoptosis in ovarian carcinoma. | Q40474530 | ||
| Protocols for regulation and study of diphosphoinositol polyphosphates. | Q40519725 | ||
| Ectopic expression of murine diphosphoinositol polyphosphate phosphohydrolase 1 attenuates signaling through the ERK1/2 pathway | Q40542484 | ||
| Golgi coatomer binds, and forms K(+)-selective channels gated by, inositol polyphosphates. | Q41455472 | ||
| Inositol hexakisphosphate kinases induce cell death in Huntington disease | Q41820993 | ||
| Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling | Q41830941 | ||
| Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain | Q42053859 | ||
| Structural identification of the myo-inositol 1,4,5-trisphosphate-binding domain in rat brain inositol 1,4,5-trisphosphate 3-kinase | Q42159660 | ||
| Inositol diphosphate signaling regulates telomere length | Q42641267 | ||
| Turnover of inositol pentakisphosphates, inositol hexakisphosphate and diphosphoinositol polyphosphates in primary cultured hepatocytes | Q42745423 | ||
| Inositol hexakisphosphate kinases promote autophagy. | Q42872768 | ||
| Phospholipid scramblase 1 potentiates the antiviral activity of interferon | Q24301128 | ||
| Toward a confocal subcellular atlas of the human proteome | Q24301129 | ||
| A conserved family of enzymes that phosphorylate inositol hexakisphosphate | Q24301881 | ||
| Crystal structure of human diphosphoinositol phosphatase 1 | Q24311982 | ||
| Glycogen synthase kinase 3: more than a namesake | Q24315635 | ||
| Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach | Q24321897 | ||
| An empirical framework for binary interactome mapping | Q24322723 | ||
| A human protein-protein interaction network: a resource for annotating the proteome | Q24324450 | ||
| Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress | Q24337620 | ||
| A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase | Q24533397 | ||
| Roles of inositol phosphates and inositol pyrophosphates in development, cell signaling and nuclear processes | Q24599387 | ||
| The IntAct molecular interaction database in 2012 | Q24621004 | ||
| A quantitative atlas of mitotic phosphorylation | Q24646817 | ||
| Effect of inositol hexakisphosphate kinase 2 on transforming growth factor beta-activated kinase 1 and NF-kappaB activation | Q24670467 | ||
| Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics | Q24672792 | ||
| Structural insight into inositol pyrophosphate turnover | Q27011244 | ||
| How inositol pyrophosphates control cellular phosphate homeostasis? | Q27016220 | ||
| Structural Studies and Protein Engineering of Inositol Phosphate Multikinase | Q27671552 | ||
| First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase | Q27674034 | ||
| Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding | Q27675827 | ||
| Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | Q27864128 | ||
| The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis | Q27929981 | ||
| Regulation of inositol metabolism is fine-tuned by inositol pyrophosphates in Saccharomyces cerevisiae | Q27930426 | ||
| TOR, a central controller of cell growth | Q27933354 | ||
| The transcriptional regulator, Arg82, is a hybrid kinase with both monophosphoinositol and diphosphoinositol polyphosphate synthase activity | Q27937722 | ||
| Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases | Q27939197 | ||
| Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases | Q28116072 | ||
| Back in the water: the return of the inositol phosphates | Q28186774 | ||
| Genetic rationale for microheterogeneity of human diphosphoinositol polyphosphate phosphohydrolase type 2 | Q28190925 | ||
| Tumor necrosis factor receptor-associated factors (TRAFs) | Q28199382 | ||
| Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate | Q28205958 | ||
| RNA-quality control by the exosome | Q28251052 | ||
| Phosphatidylinositol synthase from mammalian tissues | Q28254715 | ||
| The IHPK1 gene is disrupted at the 3p21.31 breakpoint of t(3;9) in a family with type 2 diabetes mellitus | Q28268909 | ||
| Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in epithelial cells | Q28273547 | ||
| Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase | Q28280529 | ||
| Crystal structure of the catalytic core of inositol 1,4,5-trisphosphate 3-kinase | Q28280540 | ||
| Isolation of an erythrocyte membrane protein that mediates Ca2+-dependent transbilayer movement of phospholipid | Q28282149 | ||
| Synthesis and metabolism of bis-diphosphoinositol tetrakisphosphate in vitro and in vivo | Q28300864 | ||
| neo-inositol polyphosphates in the amoeba Entamoeba histolytica | Q28375010 | ||
| GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase | Q28571302 | ||
| Molecular cloning of a novel isoform of diphosphoinositol polyphosphate phosphohydrolase: a potential target of lithium therapy | Q28581718 | ||
| Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells | Q28585161 | ||
| The Lnx family proteins function as molecular scaffolds for Numb family proteins | Q28589634 | ||
| MYC on the path to cancer | Q29619979 | ||
| Inositol hexakisphosphate kinase-2 acts as an effector of the vertebrate Hedgehog pathway | Q30497487 | ||
| Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases | Q33836143 | ||
| An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase. | Q34137530 | ||
| The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment | Q34317637 | ||
| Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death | Q34366232 | ||
| Phosphorylation of proteins by inositol pyrophosphates | Q34377316 | ||
| p53-mediated apoptosis requires inositol hexakisphosphate kinase-2 | Q34397020 | ||
| Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate | Q34454650 | ||
| The Nudix hydrolase superfamily | Q34479614 | ||
| Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2. | Q34573044 | ||
| Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase | Q34664363 | ||
| Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event | Q34688142 | ||
| Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column. | Q34734854 | ||
| Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis | Q34741451 | ||
| Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma | Q35208535 | ||
| Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy | Q35882137 | ||
| Alterations in an inositol phosphate code through synergistic activation of a G protein and inositol phosphate kinases | Q36013418 | ||
| Inositol pyrophosphates: metabolism and signaling | Q36375032 | ||
| Inositol polyphosphate multikinase signaling in the regulation of metabolism | Q36403568 | ||
| Diphosphoinositol polyphosphates: what are the mechanisms? | Q36426176 | ||
| HSP90 regulates cell survival via inositol hexakisphosphate kinase-2. | Q36446083 | ||
| Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis | Q36497226 | ||
| Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair | Q36579532 | ||
| Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate | Q36631844 | ||
| Inositol pyrophosphates as mammalian cell signals | Q36886772 | ||
| Inositol polyphosphates: a new frontier for regulating gene expression | Q36974304 | ||
| Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity | Q37012024 | ||
| Diphosphoinositol polyphosphates: metabolic messengers? | Q37268113 | ||
| Understanding inositol pyrophosphate metabolism and function: kinetic characterization of the DIPPs | Q37416185 | ||
| Are inositol pyrophosphates signalling molecules? | Q37424939 | ||
| The RASSF proteins in cancer; from epigenetic silencing to functional characterization | Q37432498 | ||
| Inositol pyrophosphates: structure, enzymology and function | Q37588509 | ||
| PPIP5K1 modulates ligand competition between diphosphoinositol polyphosphates and PtdIns(3,4,5)P3 for polyphosphoinositide-binding domains | Q37596231 | ||
| Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor | Q37635615 | ||
| Receptor-dependent compartmentalization of PPIP5K1, a kinase with a cryptic polyphosphoinositide binding domain | Q37657049 | ||
| Migraine and epilepsy: a focus on overlapping clinical, pathophysiological, molecular, and therapeutic aspects | Q37760082 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | polyphosphate | Q420783 |
| acid anhydride hydrolases | Q4674070 | ||
| phosphatidylinositol phosphate | Q73227944 | ||
| phosphotransferases (phosphate group acceptor) | Q75009726 | ||
| P304 | page(s) | 14-33 | |
| P577 | publication date | 2014-01-01 | |
| P1433 | published in | FEBS Journal | Q1388041 |
| P1476 | title | The enzymes of human diphosphoinositol polyphosphate metabolism | |
| P478 | volume | 281 |
| Q36727366 | A Novel Inositol Pyrophosphate Phosphatase in Saccharomyces cerevisiae: Siw14 PROTEIN SELECTIVELY CLEAVES THE β-PHOSPHATE FROM 5-DIPHOSPHOINOSITOL PENTAKISPHOSPHATE (5PP-IP5). |
| Q92573512 | A synthetic cyclitol-nucleoside conjugate polyphosphate is a highly potent second messenger mimic |
| Q64933186 | A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate. |
| Q37020337 | Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice |
| Q47944803 | Development of a homogenous high-throughput assay for inositol hexakisphosphate kinase 1 activity |
| Q54349708 | Discovery of InsP6-kinases as InsP6-dephosphorylating enzymes provides a new mechanism of cytosolic InsP6 degradation driven by the cellular ATP/ADP ratio. |
| Q38433610 | Global IP6K1 deletion enhances temperature modulated energy expenditure which reduces carbohydrate and fat induced weight gain |
| Q38430822 | IP6K1 Reduces Mesenchymal Stem/Stromal Cell Fitness and Potentiates High Fat Diet-Induced Skeletal Involution. |
| Q48028376 | IP6K1 is essential for chromatoid body formation and temporal regulation of Tnp2 and Prm2 expression in mouse spermatids |
| Q59604012 | Inositol Pyrophosphates: Energetic, Omnipresent and Versatile Signalling Molecules |
| Q64074443 | Inositol hexakisphosphate increases the size of platelet aggregates |
| Q37394301 | Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport |
| Q43143870 | Inositol pyrophosphates regulate RNA polymerase I-mediated rRNA transcription in Saccharomyces cerevisiae |
| Q38485691 | Polyphosphate: A Morphogenetically Active Implant Material Serving as Metabolic Fuel for Bone Regeneration |
| Q48158466 | Prometabolites of 5-Diphospho-myo-inositol Pentakisphosphate. |
| Q47637691 | Protein kinase- and lipase inhibitors of inositide metabolism deplete IP7 indirectly in pancreatic β-cells: Off-target effects on cellular bioenergetics and direct effects on IP6K activity |
| Q27684754 | Synthesis of Densely Phosphorylated Bis-1,5-Diphospho-myo-Inositol Tetrakisphosphate and its Enantiomer by Bidirectional P-Anhydride Formation |
| Q92485789 | Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP7 |
| Q27683548 | Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery |
| Q36276824 | Synthetic tools for studying the chemical biology of InsP8. |
| Q90597925 | Targeting the Inositol Pyrophosphate Biosynthetic Enzymes in Metabolic Diseases |
| Q37502964 | The "Other" Inositols and Their Phosphates: Synthesis, Biology, and Medicine (with Recent Advances in myo-Inositol Chemistry). |
| Q26786441 | The emerging roles of inositol pyrophosphates in eukaryotic cell physiology |
| Q47250401 | The inositol pyrophosphate pathway in health and diseases |
| Q44875454 | Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants |
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