| human | Q5 |
| P269 | IdRef ID | 221583912 |
| P496 | ORCID iD | 0000-0001-8355-4065 |
| P3829 | Publons author ID | 2714946 |
| P1053 | ResearcherID | G-5873-2012 |
| P1153 | Scopus author ID | 16185252300 |
| P214 | VIAF ID | 301451607 |
| P166 | award received | Fellow of the American Association for the Advancement of Science | Q5442484 |
| P69 | educated at | George Washington University | Q432637 |
| P108 | employer | Harvard Medical School | Q49121 |
| Weill Cornell Medicine | Q3567094 | ||
| Boston Children's Hospital | Q1000479 | ||
| University of Connecticut School of Medicine | Q18706195 | ||
| P734 | family name | Hla | Q37194708 |
| Hla | Q37194708 | ||
| Hla | Q37194708 | ||
| P735 | given name | Timothy | Q15885954 |
| Timothy | Q15885954 | ||
| P106 | occupation | researcher | Q1650915 |
| P21 | sex or gender | male | Q6581097 |
| Q35126551 | 15-deoxy-delta(12,14)-PGJ(2) induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats |
| Q42717085 | A festschrift for J. Martyn Bailey, a biochemist extraordinaire |
| Q40777268 | Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis |
| Q45423411 | An engineered S1P chaperone attenuates hypertension and ischemic injury. |
| Q33945064 | An update on the biology of sphingosine 1-phosphate receptors. |
| Q46882679 | Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization |
| Q36620813 | Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis. |
| Q35962030 | Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma. |
| Q39514716 | Assessment of sphingosine-1-phosphate activity in biological samples by receptor internalization and adherens junction formation |
| Q42611931 | Bioluminescence imaging of G protein-coupled receptor activation in living mice. |
| Q28344848 | Bisphenol A diglycidyl ether (BADGE) is a PPARgamma agonist in an ECV304 cell line |
| Q35362267 | C16:0-ceramide signals insulin resistance |
| Q92402334 | CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration |
| Q46556864 | COX-2 inhibitors and genetic background reduce mammary tumorigenesis in cyclooxygenase-2 transgenic mice |
| Q27016109 | Cardiac and vascular effects of fingolimod: mechanistic basis and clinical implications |
| Q46123554 | Cell biology. The ABCs of lipophile transport |
| Q28143704 | Characterization of a novel sphingosine 1-phosphate receptor, Edg-8 |
| Q24312108 | Characterization of edg-2, a human homologue of the Xenopus maternal transcript G10 from endothelial cells |
| Q33890360 | Coexpression of phosphotyrosine-containing proteins, platelet-derived growth factor-B, and fibroblast growth factor-1 in situ in synovial tissues of patients with rheumatoid arthritis and Lewis rats with adjuvant or streptococcal cell wall arthritis |
| Q44912029 | Constitutive expression of the S1P1 receptor in adult tissues. |
| Q42334089 | Correction: TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1. |
| Q27863328 | Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition. |
| Q34132261 | Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids. |
| Q35574131 | Cyclooxygenase-2 modulates cellular growth and promotes tumorigenesis. |
| Q53359627 | Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma. |
| Q42507950 | Deafness and stria vascularis defects in S1P2 receptor-null mice. |
| Q33583306 | Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation |
| Q44837709 | Differential recovery of prostacyclin synthesis in cultured vascular endothelial vs. smooth muscle cells after inactivation of cyclooxygenase with aspirin |
| Q42450714 | Dissociation of basal turnover and cytokine-induced transcript stabilization of the human cyclooxygenase-2 mRNA by mutagenesis of the 3'-untranslated region |
| Q80065659 | Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity |
| Q34777377 | ELAVL1 modulates transcriptome-wide miRNA binding in murine macrophages |
| Q34793205 | ELAVL1 regulates alternative splicing of eIF4E transporter to promote postnatal angiogenesis |
| Q40034911 | EP2 and EP4 receptors regulate aromatase expression in human adipocytes and breast cancer cells. Evidence of a BRCA1 and p300 exchange |
| Q37609429 | Elavl1a regulates zebrafish erythropoiesis via posttranscriptional control of gata1. |
| Q35535621 | Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy |
| Q77841261 | Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2 |
| Q92976926 | Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy |
| Q27667968 | Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M |
| Q42741842 | Engagement of S1P₁-degradative mechanisms leads to vascular leak in mice |
| Q35140010 | Erythrocyte-derived sphingosine 1-phosphate is essential for vascular development |
| Q35925633 | Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina. |
| Q37452251 | Essential role of the RNA-binding protein HuR in progenitor cell survival in mice. |
| Q47798594 | Evaluation of strategies to improve village chicken production: controlled field trials to assess effects of Newcastle disease vaccination and altered chick rearing in Myanmar [corrected]. |
| Q53407074 | Expression of cyclooxygenase-2 in prostate carcinoma. |
| Q40763807 | Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation |
| Q42026885 | Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient |
| Q35804361 | FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function. |
| Q43605488 | Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2. |
| Q36762973 | Fine-tuning S1P therapeutics |
| Q36236992 | Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development |
| Q43260980 | Galpha(q)-mediated plasma membrane translocation of sphingosine kinase-1 and cross-activation of S1P receptors. |
| Q37193633 | Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis |
| Q36228986 | Genomic insights into mediator lipidomics. |
| Q36623447 | HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1 to limit vascular inflammation |
| Q35862820 | HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation |
| Q42801752 | HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism |
| Q52035056 | HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice. |
| Q92964438 | Identification of ApoA4 as a sphingosine 1-phosphate chaperone in ApoM- and albumin-deficient mice |
| Q46693636 | Immunology. Dietary factors and immunological consequences |
| Q40181150 | Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor |
| Q35596079 | In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis. |
| Q34565310 | Individual variation of human S1P₁ coding sequence leads to heterogeneity in receptor function and drug interactions |
| Q30438371 | Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2 |
| Q41980679 | Induction of chemokine (C-C motif) ligand 2 by sphingosine-1-phosphate signaling in neuroblastoma |
| Q28505206 | Induction of cyclooxygenase-2 in macrophages by catalase: role of NF-kappaB and PI3K signaling pathways |
| Q34808316 | Induction of cyclooxygenase-2 in monocyte/macrophage by mucins secreted from colon cancer cells. |
| Q71736211 | Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: a potential mechanism for inflammatory angiogenesis |
| Q28297849 | Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN |
| Q73642418 | Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis |
| Q34748080 | Inhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation. |
| Q30429523 | International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature |
| Q28201589 | International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature |
| Q34205259 | Intestinal epithelial HuR modulates distinct pathways of proliferation and apoptosis and attenuates small intestinal and colonic tumor development |
| Q40711739 | Intimal smooth muscle cells as a target for peroxisome proliferator-activated receptor-gamma ligand therapy |
| Q35242288 | Knock out of S1P3 receptor signaling attenuates inflammation and fibrosis in bleomycin-induced lung injury mice model |
| Q40685221 | Leptomycin B, an inhibitor of the nuclear export receptor CRM1, inhibits COX-2 expression |
| Q92418250 | Lysolipid receptor cross-talk regulates lymphatic endothelial junctions in lymph nodes |
| Q42540355 | Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist |
| Q28208260 | Lysophospholipids--receptor revelations |
| Q41943814 | Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics |
| Q35904529 | Maternal or zygotic sphingosine kinase is required to regulate zebrafish cardiogenesis |
| Q28295523 | Molecular characterization of the 5.2 KB isoform of the human cyclooxygenase-1 transcript |
| Q45396255 | Mortality rates adjusted for unobserved deaths and associations with Newcastle disease virus serology among unvaccinated village chickens in Myanmar |
| Q27315147 | Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure |
| Q80022540 | Normal acute and chronic inflammatory responses in sphingosine kinase 1 knockout mice |
| Q34764480 | Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland |
| Q40917355 | Overexpression of cyclooxygenase-2 induces cell cycle arrest. Evidence for a prostaglandin-independent mechanism |
| Q73693790 | Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice |
| Q37144609 | PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer. |
| Q24555751 | PTEN as an effector in the signaling of antimigratory G protein-coupled receptor |
| Q42789241 | Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice |
| Q34227743 | Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability. |
| Q35844027 | Physiological and pathological actions of sphingosine 1-phosphate. |
| Q40680453 | Platelet-derived growth factor (PDGF)-induced chemotaxis does not require the G protein-coupled receptor S1P1 in murine embryonic fibroblasts and vascular smooth muscle cells |
| Q42583666 | Plugging vascular leak by sphingosine kinase from bone marrow progenitor cells |
| Q38203145 | Post-transcriptional gene regulation by HuR and microRNAs in angiogenesis |
| Q80138091 | Prostaglandins & other lipid mediators: a new phase, a new team |
| Q64377639 | Protein kinase Calpha and sphingosine 1-phosphate-dependent signaling in endothelial cell |
| Q42946822 | Ramping up RANTES in the acute response to arterial injury |
| Q70059641 | Reconstituted U1 small nuclear ribonucleoprotein complex restores 5' splice site cleavage activity |
| Q38339080 | Recovery of mitogenic activity of a growth factor mutant with a nuclear translocation sequence. |
| Q69906336 | Recovery of prostacyclin synthesis in human vascular endothelial cells following intermittent or continuous exposure to indomethacin |
| Q34442283 | Regulation of a vascular plexus by gata4 is mediated in zebrafish through the chemokine sdf1a |
| Q34310949 | Regulation of limb development by the sphingosine 1-phosphate receptor S1p1/EDG-1 occurs via the hypoxia/VEGF axis. |
| Q35551835 | Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors |
| Q64378573 | Regulation of vascular endothelial cell growth factor expression in mouse mammary tumor cells by the EP2 subtype of the prostaglandin E2 receptor |
| Q37415111 | Regulation of vascular physiology and pathology by the S1P2 receptor subtype. |
| Q24563464 | Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference |
| Q38324717 | Role of guanine nucleotide exchange factor P-Rex-2b in sphingosine 1-phosphate-induced Rac1 activation and cell migration in endothelial cells. |
| Q36409037 | S1P and the birth of platelets. |
| Q27000974 | S1P control of endothelial integrity |
| Q30434737 | S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor |
| Q41855132 | S1P/S1P2 signaling induces cyclooxygenase-2 expression in Wilms tumor |
| Q40405662 | S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate |
| Q73525194 | Selective inhibition of cyclooxygenase-2 with antisense oligodeoxynucleotide restricts induction of rat adjuvant-induced arthritis |
| Q40854466 | Serum withdrawal-induced post-transcriptional stabilization of cyclooxygenase-2 mRNA in MDA-MB-231 mammary carcinoma cells requires the activity of the p38 stress-activated protein kinase |
| Q80837423 | Signaling through 3',5'-cyclic adenosine monophosphate and phosphoinositide-3 kinase induces sodium/iodide symporter expression in breast cancer |
| Q40428950 | SnapShot: Bioactive lysophospholipids |
| Q30425699 | Sphingolipid modulation of angiogenic factor expression in neuroblastoma |
| Q26992148 | Sphingolipid signaling in metabolic disorders |
| Q39398031 | Sphingosine 1-phosphate (S1P)/S1P receptor 1 signaling regulates receptor activator of NF-κB ligand (RANKL) expression in rheumatoid arthritis. |
| Q37845624 | Sphingosine 1-phosphate (S1P): Physiology and the effects of S1P receptor modulation. |
| Q43559665 | Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells |
| Q37909176 | Sphingosine 1-phosphate in coagulation and inflammation. |
| Q36561924 | Sphingosine 1-phosphate receptor signaling regulates proper embryonic vascular patterning. |
| Q29013537 | Sphingosine 1-phosphate receptors |
| Q26852942 | Sphingosine 1-phosphate signalling |
| Q89855423 | Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta |
| Q40310155 | Sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 signaling in rheumatoid synovium: regulation of synovial proliferation and inflammatory gene expression. |
| Q90780837 | Sphingosine 1-phosphate: Lipid signaling in pathology and therapy |
| Q34094319 | Sphingosine interaction with acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) regulates PP2A activity and cyclooxygenase (COX)-2 expression in human endothelial cells. |
| Q36026708 | Sphingosine kinase 1 is a critical component of the copper-dependent FGF1 export pathway |
| Q37289270 | Sphingosine kinases are not required for inflammatory responses in macrophages |
| Q27011857 | Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond |
| Q41570690 | Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis |
| Q46896285 | Sphingosine-1-phosphate signaling regulates lamellipodia localization of cortactin complexes in endothelial cells |
| Q33697778 | Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger? |
| Q35839016 | Structural and functional characteristics of S1P receptors. |
| Q36624553 | TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1 |
| Q73075512 | TWEAK is an endothelial cell growth and chemotactic factor that also potentiates FGF-2 and VEGF-A mitogenic activity |
| Q34175167 | The BCL6 RD2 domain governs commitment of activated B cells to form germinal centers |
| Q40427696 | The G protein-coupled receptor S1P2 regulates Rho/Rho kinase pathway to inhibit tumor cell migration |
| Q47963945 | The RNA-binding protein HuR regulates the expression of cyclooxygenase-2. |
| Q81057981 | The dawn of lipidomics |
| Q38342712 | The immediate-early gene product MAD-3/EDG-3/IkappaB alpha is an endogenous modulator of fibroblast growth factor-1 (FGF-1) dependent human endothelial cell growth. |
| Q54215788 | Treatment with the immunomodulator FTY720 (fingolimod) significantly reduces renal inflammation in murine unilateral ureteral obstruction. |
| Q73596269 | Tumorigenic transformation of immortalized ECV endothelial cells by cyclooxygenase-1 overexpression |
| Q43251117 | Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells. |
| Q22010773 | Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate |
| Q33378571 | Vascular endothelium as a contributor of plasma sphingosine 1-phosphate |
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