Pramlintide regulation of extracellular matrix (ECM) and apoptosis through mitochondrial-dependent pathways in human nucleus pulposus cells.

scientific article published in December 2017

Pramlintide regulation of extracellular matrix (ECM) and apoptosis through mitochondrial-dependent pathways in human nucleus pulposus cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/0394632017747500
P932PMC publication ID5849218
P698PubMed publication ID29256292

P2093author name stringWei Liu
Kun Wang
Shuai Li
Cao Yang
Zengwu Shao
Yu Song
Xianzhe Liu
Suyun Li
Xinghuo Wu
Wenbin Hua
Yunkun Zhang
P2860cites workPrevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blockedQ24318845
Matrix metalloproteinasesQ28140451
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosisQ29616513
Mitochondrial control of cell deathQ29617739
Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistryQ29618605
Superoxide flashes: early mitochondrial signals for oxidative stress-induced apoptosisQ30503211
Oxygen and lactate concentrations measured in vivo in the intervertebral discs of patients with scoliosis and back painQ32127020
Cadmium induces Ca2+ mediated, calpain-1/caspase-3-dependent apoptosis in primary cultured rat proximal tubular cellsQ32178244
Role of mitochondrial pathway in compression-induced apoptosis of nucleus pulposus cellsQ34185342
Amylin replacement with pramlintide as an adjunct to insulin therapy in type 1 and type 2 diabetes mellitus: a physiological approach toward improved metabolic controlQ34319280
Effects of low oxygen concentrations and metabolic inhibitors on proteoglycan and protein synthesis rates in the intervertebral discQ34506672
GLP-1R and amylin agonism in metabolic disease: complementary mechanisms and future opportunitiesQ36153247
Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degenerationQ36579434
AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stressQ36713683
Matrix synthesis and degradation in human intervertebral disc degeneration.Q36883824
Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc.Q37350940
Cadmium induces intracellular Ca2+- and H2O2-dependent apoptosis through JNK- and p53-mediated pathways in skin epidermal cell lineQ37478131
Rottlerin-induced autophagy leads to the apoptosis in breast cancer stem cells: molecular mechanisms.Q37556841
Hypoxic regulation of nucleus pulposus cell survival: from niche to notchQ37687706
Intervertebral disk nutrition: a review of factors influencing concentrations of nutrients and metabolitesQ37938103
Potential crosstalk of Ca2+-ROS-dependent mechanism involved in apoptosis of Kasumi-1 cells mediated by heme oxygenase-1 small interfering RNA.Q38955549
Herbacetin induces apoptosis in HepG2 cells: Involvements of ROS and PI3K/Akt pathwayQ39260049
Nutrition of the intervertebral disc: solute transport and metabolismQ39345516
Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastomaQ39374075
Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: implications in degenerative disc diseaseQ39475834
2001 Volvo Award Winner in Basic Science Studies: Effect of nutrient supply on the viability of cells from the nucleus pulposus of the intervertebral discQ39586800
Primary cilia regulate mTORC1 activity and cell size through Lkb1.Q39640418
IL-1β induces apoptosis and autophagy via mitochondria pathway in human degenerative nucleus pulposus cellsQ41917826
Involvement of a region near valine-69 of tissue inhibitor of metalloproteinases (TIMP)-1 in the interaction with matrix metalloproteinase 3 (stromelysin 1).Q41970870
Phenotypic characteristics of the nucleus pulposus: expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2.Q44055318
The influence of diabetes mellitus on lumbar intervertebral disk herniationQ44185241
Effects of pramlintide on postprandial glucose excursions and measures of oxidative stress in patients with type 1 diabetesQ45285721
Pyrroloquinoline quinone protects nucleus pulposus cells from hydrogen peroxide-induced apoptosis by inhibiting the mitochondria-mediated pathwayQ46821074
Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironmentQ46891204
Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition.Q48869814
Lumbar discectomy and the diabetic patient: incidence and outcome.Q53488284
Analysis of aging and degeneration of the human intervertebral disc. Comparison of surgical specimens with normal controls.Q54140305
Changes in proteoglycans of intervertebral disc in diabetic patients. A possible cause of increased back painQ74528667
In situ oxygen utilization in the rat intervertebral discQ79852992
Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral diskQ80177979
Primer on pramlintide, an amylin analogQ83798786
Diabetes mellitus as a risk factor for the development of lumbar spinal stenosisQ84181321
Effect of hyperglycemia on apoptosis of notochordal cells and intervertebral disc degeneration in diabetic ratsQ84967415
P921main subjectextracellular matrixQ193825
P304page(s)394632017747500
P577publication date2017-12-19
P1433published inInternational Journal of Immunopathology and PharmacologyQ15752195
P1476titlePramlintide regulation of extracellular matrix (ECM) and apoptosis through mitochondrial-dependent pathways in human nucleus pulposus cells
P478volume31

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Q92925351Neuroprotective Effects of the Amylin Analog, Pramlintide, on Alzheimer's Disease Are Associated with Oxidative Stress Regulation Mechanismscites workP2860

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