Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats

scientific article published in January 1996

Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats is …
instance of (P31):
scholarly articleQ13442814

External links are
P698PubMed publication ID8569201

P2093author name stringKrajewski S
Reed JC
Cheng W
Anversa P
Kajstura J
Clark WA
Sonnenblick EH
Olivetti G
Reiss K
P433issue1
P921main subjectapoptotic processQ14599311
P304page(s)86-107
P577publication date1996-01-01
P1433published inLaboratory InvestigationQ6467260
P1476titleApoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats
P478volume74

Reverse relations

cites work (P2860)
Q46800364(99m)Tc-annexin V and (111)In-antimyosin antibody uptake in experimental myocardial infarction in rats
Q4468702118F-labelled annexin V: a PET tracer for apoptosis imaging
Q3396270120-Hydroxyeicosatetraenoic acid induces apoptosis in neonatal rat cardiomyocytes through mitochondrial-dependent pathways
Q27667526A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes
Q33836284A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury
Q33293545A novel dual staining method for identification of apoptotic cells reveals a modest apoptotic response in infarcted mouse myocardium
Q45143633AT2 receptor and apoptosis during AT1 receptor blockade in reperfused myocardial infarction in the rat.
Q38637311Abnormalities in Alternative Splicing of Apoptotic Genes and Cardiovascular Diseases
Q34997854Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy
Q40746819Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress
Q24606408Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice
Q53469228Administration of zinc complex of acetylsalicylic acid after the onset of myocardial injury protects the heart by upregulation of antioxidant enzymes.
Q47677058Age and ischemia differentially impact mitochondrial ultrastructure and function in a novel model of age-associated estrogen deficiency in the female rat heart
Q39870130Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart.
Q41811962Analysis of region specific gene expression patterns in the heart and systemic responses after experimental myocardial ischemia
Q35949609Angiogenic signal during cardiac repair
Q35043224Anti-apoptotic effect of benidipine, a long-lasting vasodilating calcium antagonist, in ischaemic/reperfused myocardial cells
Q42285436Antiapoptotic mechanisms of benidipine in the ischemic/reperfused heart
Q37397983Antineoplastic-related cardiotoxicity, morphofunctional aspects in a murine model: contribution of the new tool 2D-speckle tracking.
Q42078470Apoptosis after reperfused myocardial infarction: Role of angiotensin II.
Q36080910Apoptosis and oncosis in acute coronary syndromes: assessment and implications
Q81576039Apoptosis at a distance: remote activation of caspase-3 occurs early after myocardial infarction
Q41343462Apoptosis in cardiovascular disease
Q30846548Apoptosis in dilated cardiomyopathy
Q22242031Apoptosis in myocardial ischaemia and infarction
Q34629107Apoptosis in the cardiovascular system
Q41280990Apoptosis in the heart: when and why?
Q41307431Apoptosis induced by parasitic diseases
Q28511114Apoptosis repressor with a CARD domain (ARC) restrains Bax-mediated pathogenesis in dystrophic skeletal muscle
Q92617006Atractylodesin III maintains mitochondrial function and inhibits caspase-3 activity to reverse apoptosis of cardiomyocytes in AMI rats
Q95821296Atrial fibrillation and atrial fibrosis
Q36278847BNIP3 promotes calcium and calpain-dependent cell death
Q36234120Biochemical dysfunction in heart mitochondria exposed to ischaemia and reperfusion
Q64977982Blockade of RBP-J-Mediated Notch Signaling Pathway Exacerbates Cardiac Remodeling after Infarction by Increasing Apoptosis in Mice.
Q37650499Both castration and goserelin acetate ameliorate myocardial ischemia reperfusion injury and apoptosis in male rats
Q36933115CRYAB and HSPB2 deficiency alters cardiac metabolism and paradoxically confers protection against myocardial ischemia in aging mice
Q37986552Cardiac cell therapy: boosting mesenchymal stem cells effects
Q37221281Cardiac oxidative stress and remodeling following infarction: role of NADPH oxidase
Q35075553Cardiac remodeling and physical training post myocardial infarction
Q37836529Cardiomyocyte death: insights from molecular and microstructural magnetic resonance imaging
Q35657122Cardiomyocyte death: mechanisms and translational implications
Q42178032Cardioprotective effects of alpha-lipoic Acid on myocardial reperfusion injury: suppression of reactive oxygen species generation and activation of mitogen-activated protein kinase
Q33785805Cardiotrophin-1 (CT-1): a novel hypertrophic and cardioprotective agent
Q37567882Caspase inhibition protects against reovirus-induced myocardial injury in vitro and in vivo
Q42571029Cell death, dysglycemia and myocardial infarction
Q41765213Cell penetrating peptide conjugated bioreducible polymer for siRNA delivery
Q35764091Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion
Q36635808Characterization of the structural and functional changes in the myocardium following focal ischemia-reperfusion injury
Q41832646Co-expression of POU4F2/Brn-3b with p53 may be important for controlling expression of pro-apoptotic genes in cardiomyocytes following ischaemic/hypoxic insults
Q46211547Combination of necroptosis and apoptosis inhibition enhances cardioprotection against myocardial ischemia-reperfusion injury
Q48116601Concepts of tissue injury and cell death in inflammation: a historical perspective
Q40218554Correlation between apoptosis and left ventricular remodeling in subacute phase of myocardial ischemia and reperfusion
Q33815808Cyclophilins and their possible role in the stress response
Q37575962Cyclosporin A in left ventricular remodeling after myocardial infarction
Q33863961Cytokines and their receptors in cardiovascular diseases--role of gp130 signalling pathway in cardiac myocyte growth and maintenance
Q35772306Deficiency of beta1 integrins results in increased myocardial dysfunction after myocardial infarction
Q57035159Divergent Effects of Cyclophilin-D Inhibition on the Female Rat Heart: Acute Versus Chronic Post-Myocardial Infarction
Q35695495Dose-dependent apoptotic and necrotic myocyte death induced by the beta2-adrenergic receptor agonist, clenbuterol
Q36437704Dual delivery of hepatocyte and vascular endothelial growth factors via a protease-degradable hydrogel improves cardiac function in rats
Q28345320Dynamic process of apoptosis in adult rat cardiomyocytes analyzed using 48-hour videomicroscopy and electron microscopy: beating and rate are associated with the apoptotic process
Q92572385E3-ubiquitin ligase TRIM6 aggravates myocardial ischemia/reperfusion injury via promoting STAT1-dependent cardiomyocyte apoptosis
Q33862492Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction
Q37222474Effect of carvedilol on cardiomyocyte apoptosis in a rat model of myocardial infarction: a role for toll-like receptor 4.
Q37956569Effect of erythropoiesis-stimulating agents in acute ST-segment elevation myocardial infarction: a systematic review
Q24813684Effect of the degree of ischaemic injury and reoxygenation time on the type of myocardial cell death in man: role of caspases
Q34088930Effects of ACE2 Inhibition in the Post-Myocardial Infarction Heart
Q40484694Effects of Shenqi Fuzheng injection on Fas/FasL protein expression levels in the cardiomyocytes of a mouse model of viral myocarditis
Q36977754Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction
Q37379734Enhanced expression of p53 and apoptosis induced by blockade of the vacuolar proton ATPase in cardiomyocytes
Q30498584Enhancing or eliminating signals for cell survival to treat disease.
Q26853220Epigenetic mechanisms underlying cardiac degeneration and regeneration
Q27334040Epoxyeicosatrienoic acid analogue mitigates kidney injury in a rat model of radiation nephropathy.
Q36389505Evans blue staining of cardiomyocytes induced by myocardial contrast echocardiography in rats: evidence for necrosis instead of apoptosis
Q35377410Exercise induced myocardial ischaemia does not cause increase in C-reactive protein concentration
Q50461855Exogenous midkine administration prevents cardiac remodeling in pacing-induced congestive heart failure of rabbits.
Q33656526Extracellular ubiquitin increases expression of angiogenic molecules and stimulates angiogenesis in cardiac microvascular endothelial cells
Q37518459Feasibility Study on Cardiac Arrhythmia Ablation Using High-Energy Heavy Ion Beams.
Q47377679Gene transfer of the pancaspase inhibitor P35 reduces myocardial infarct size and improves cardiac function
Q54472406Ginkgo biloba extract reducing myocardium cells apoptosis by regulating apoptotic related proteins expression in myocardium tissues.
Q37777353Granulocyte colony-stimulating factor for ischemic heart failure: should we use it?
Q42041495H11 has dose-dependent and dual hypertrophic and proapoptotic functions in cardiac myocytes.
Q35753015Hsp70 may protect cardiomyocytes from stress-induced injury by inhibiting Fas-mediated apoptosis
Q49721098Hyperpolarized [1,4-13C2]Fumarate Enables Magnetic Resonance-Based Imaging of Myocardial Necrosis
Q28577311Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.
Q33853515Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or a pH shift and is independent of p53.
Q42209981IL-17A promotes ventricular remodeling after myocardial infarction
Q39019273Immunohistochemical detection of early myocardial infarction: a systematic review
Q73304076Immunohistochemical study on tissue transglutaminase and copper-zinc superoxide dismutase in human myocardium: its relevance to apoptosis detected by the nick end labelling method
Q35782103In situ apoptosis assay for the detection of early acute myocardial infarction
Q34717828In vivo gene delivery of XIAP protects against myocardial apoptosis and infarction following ischemia/reperfusion in conscious rabbits
Q82387591Induction of cardiomyocyte apoptosis by anti-cardiac myosin heavy chain antibodies in patients with acute myocardial infarction
Q91940252Influence of the plasminogen activator system on necrosis in acute myocardial infarction: analysis of urokinase- and urokinase receptor-knockout mouse models
Q42236378Inhibition of mitochondrial calcium-independent phospholipase A2 (iPLA2) attenuates mitochondrial phospholipid loss and is cardioprotective
Q35377119Interleukin 18 in acute myocardial infarction
Q37556429Interleukin-37 and Dendritic Cells Treated With Interleukin-37 Plus Troponin I Ameliorate Cardiac Remodeling After Myocardial Infarction
Q34497101Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury
Q36182799Involvement of AQP 1 in the cardio-protective effect of remifentanil post-conditioning in ischemia/reperfusion rats
Q28576800Involvement of GADD153 and cardiac ankyrin repeat protein in cardiac ischemia-reperfusion injury
Q36152106Involvement of UTP in protection of cardiomyocytes from hypoxic stress.
Q77418496Ischemic preconditioning attenuates apoptotic cell death associated with ischemia/reperfusion
Q34654773Lack of type XV collagen causes a skeletal myopathy and cardiovascular defects in mice
Q47395547Local delivery of soluble TNF-alpha receptor 1 gene reduces infarct size following ischemia/reperfusion injury in rats
Q37308645Matrix metalloproteinases: drug targets for myocardial infarction
Q50492371Mechanism of cell death of rat cardiac fibroblasts induced by serum depletion
Q35697472Mechanisms of apoptosis in the heart
Q37330076Mechanisms of cell death in heart disease
Q34234464Mesenchymal stromal cells: current understanding and clinical status
Q33713970Methotrexate carried in lipid core nanoparticles reduces myocardial infarction size and improves cardiac function in rats.
Q28280031Micronized purified flavonoid fraction in pretreating CABG patients
Q38019459Mitochondria in heart failure: the emerging role of mitochondrial dynamics
Q35492308Mitochondria to nucleus translocation of AIF in mice lacking Hsp70 during ischemia/reperfusion
Q90187491Mitochondrial and mitochondrial-independent pathways of myocardial cell death during ischaemia and reperfusion injury
Q37054218Mitochondrial centrality in heart failure
Q33596970Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach
Q36019004Molecular MRI of acute necrosis with a novel DNA-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium
Q37428313Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed-enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia
Q24814079Molecular and cellular mechanisms of cardiotoxicity
Q48221861Molecular imaging of cardiac remodelling after myocardial infarction
Q49835908Molecular tissue changes in early myocardial ischemia: from pathophysiology to the identification of new diagnostic markers.
Q36430856Morphological aspects of apoptosis in heart diseases
Q30438207Multimodality cardiovascular molecular imaging, Part II
Q77083012Myocardial DNA strand breaks are detected in biopsy tissues from patients with dilated cardiomyopathy
Q35213048Myocardial ischemia activates an injurious innate immune signaling via cardiac heat shock protein 60 and Toll-like receptor 4.
Q33712155Myocardial preconditioning: basic concepts and potential mechanisms.
Q39790463Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53
Q42194690Myocyte apoptosis occurs early during the development of pressure-overload hypertrophy in infant myocardium
Q37959805New roles for mitochondria in cell death in the reperfused myocardium
Q41375785Nipping at cardiac remodeling.
Q37465955Nogo-C regulates cardiomyocyte apoptosis during mouse myocardial infarction
Q35776857Noninvasive imaging of myocyte apoptosis following application of a stem cell-engineered delivery platform to acutely infarcted myocardium
Q53442597Nucleostemin exerts anti-apoptotic function via p53 signaling pathway in cardiomyocytes.
Q36800968Optimal time for mesenchymal stem cell transplantation in rats with myocardial infarction
Q37090521Over-expression of a modified bifunctional apoptosis regulator protects against cardiac injury and doxorubicin-induced cardiotoxicity in transgenic mice
Q42092061Overexpression of IAP-2 attenuates apoptosis and protects against myocardial ischemia/reperfusion injury in transgenic mice
Q92469263Overexpression of TGR5 alleviates myocardial ischemia/reperfusion injury via AKT/GSK-3β mediated inflammation and mitochondrial pathway
Q37373506Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy
Q36952671Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo
Q43233333Overexpression of the NHE1 isoform of the Na(+)/H (+) exchanger causes elevated apoptosis in isolated cardiomyocytes after hypoxia/reoxygenation challenge
Q50917391Persistence of apoptosis and inflammatory responses in the heart and bone marrow of mice following whole-body exposure to ²⁸Silicon (²⁸Si) ions.
Q37364441Prevention of ischemia/reperfusion-induced cardiac apoptosis and injury by melatonin is independent of glutathione peroxdiase 1.
Q37051197Programmed cell death in cardiac myocytes: strategies to maximize post-ischemic salvage.
Q53600996Protection against myocardial ischemia/reperfusion injury by short-term diabetes: enhancement of VEGF formation, capillary density, and activation of cell survival signaling.
Q33346851Protective effect of ultra low molecular weight heparin on glutamate-induced apoptosis in cortical cells
Q33678033Protein Kinases as Drug Development Targets for Heart Disease Therapy
Q28084341Quality control systems in cardiac aging
Q33559727RAGE modulates hypoxia/reoxygenation injury in adult murine cardiomyocytes via JNK and GSK-3beta signaling pathways.
Q43192890Reduction of cardiac cell death after helium postconditioning in rats: transcriptional analysis of cell death and survival pathways
Q46405553Reduction of myocardial infarct size by doxycycline: a role for plasmin inhibition
Q36281111Regression of pathological cardiac hypertrophy: signaling pathways and therapeutic targets
Q78130140Regulation of cardiomyocyte apoptosis in ischemic reperfused mouse heart by glutathione peroxidase
Q36980730Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase
Q34531697Resveratrol attenuates ischemia/reperfusion injury in neonatal cardiomyocytes and its underlying mechanism
Q64085233Retinol palmitate protects against myocardial ischemia/reperfusion injury via reducing oxidative stress and inhibiting apoptosis
Q46843785Shift toward greater pathologic post-myocardial infarction remodeling with loss of the adaptive hypertrophic signaling of alpha1 adrenergic receptors in mice.
Q52583529Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart.
Q36623740TNF-alpha is involved in activating DNA fragmentation in skeletal muscle
Q35113470Targeting extracellular DNA to deliver IGF-1 to the injured heart
Q42937750Tempero-spatial dissociation between the expression of Fas and apoptosis after coronary occlusion
Q53306185Temporal cardiac remodeling post-myocardial infarction: dynamics and prognostic implications in personalized medicine.
Q37039373The E-domain region of mechano-growth factor inhibits cellular apoptosis and preserves cardiac function during myocardial infarction
Q41110486The Effects of Diabetes Induction on the Rat Heart: Differences in Oxidative Stress, Inflammatory Cells, and Fibrosis between Subendocardial and Interstitial Myocardial Areas.
Q37117825The discovery of a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1) for ischemic heart: synthesis, activity and target identification
Q37240181The effect of dietary red palm oil on the functional recovery of the ischaemic/reperfused isolated rat heart: the involvement of the PI3-kinase signaling pathway
Q35987663The late phase of ischemic preconditioning induces a prosurvival genetic program that results in marked attenuation of apoptosis
Q91582380The long non-coding RNA TUG1-miR-9a-5p axis contributes to ischemic injuries by promoting cardiomyocyte apoptosis via targeting KLF5
Q37139791The magnitude and temporal dependence of apoptosis early after myocardial ischemia with or without reperfusion
Q53287018The protective effect of peony extract on acute myocardial infarction in rats
Q37194572The rationale for cardiomyocyte resuscitation in myocardial salvage
Q34954474The role and modulation of autophagy in experimental models of myocardial ischemia-reperfusion injury
Q34329506The role of apoptotic cell death in cardiovascular disease
Q37088298Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart
Q36915712Towards comprehensive cardiac repair and regeneration after myocardial infarction: Aspects to consider and proteins to deliver.
Q37362206Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death
Q96127259Uptake, efflux, and toxicity of inorganic and methyl mercury in the endothelial cells (EA.hy926)
Q35900913VEGFR1 (Flt-1+/-) gene knockout leads to the disruption of VEGF-mediated signaling through the nitric oxide/heme oxygenase pathway in ischemic preconditioned myocardium
Q78019259[Apoptosis--what is it? Significance in coronary heart disease and myocardial infarct]
Q52535812[Cell death in inflammatory heart muscle diseases--apoptosis or necrosis?].
Q34004496c-Kit+ bone marrow stem cells differentiate into functional cardiac myocytes.
Q37368100p53 and the hypoxia-induced apoptosis of cultured neonatal rat cardiac myocytes
Q42122625p53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation.

Search more.