p53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation.

scientific article published on October 2013

p53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/EMMM.201202055
P932PMC publication ID3840484
P698PubMed publication ID24096875
P5875ResearchGate publication ID257463668

P50authorRajan GognaQ57080049
Mahmood KhanQ59677528
P2093author name stringPeriannan Kuppusamy
Esha Madan
Uttam Pati
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A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damageQ28138556
Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen speciesQ28209399
The ubiquitin ligase COP1 is a critical negative regulator of p53Q28258057
Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing pumaQ28281602
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Gallium compound GaQ(3) -induced Ca(2+) signalling triggers p53-dependent and -independent apoptosis in cancer cellsQ28387391
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p53: puzzle and paradigmQ29618407
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Leptin protects cardiomyocytes from serum-deprivation-induced apoptosis by increasing anti-oxidant defence.Q33608137
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Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability.Q34146784
Reperfusion injury induces apoptosis in rabbit cardiomyocytesQ34190792
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p53 activation mediates polyglutamine-expanded ataxin-3 upregulation of Bax expression in cerebellar and pontine nuclei neuronsQ82531291
Hyperbaric oxygen preconditioning improves myocardial function, reduces length of intensive care stay, and limits complications post coronary artery bypass graft surgeryQ82769972
Reactive oxygen species-mediated p53 core-domain modifications determine apoptotic or necrotic death in cancer cellsQ82826929
The cell cycle-regulated protein human GTSE-1 controls DNA damage-induced apoptosis by affecting p53 function.Q34197362
P53-mediated induction of Cox-2 counteracts p53- or genotoxic stress-induced apoptosisQ34207195
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The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogeneQ34462232
Intramyocardial injection of vascular endothelial growth factor-A165 plasmid followed by granulocyte-colony stimulating factor to induce angiogenesis in patients with severe chronic ischaemic heart disease.Q34545357
Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitorsQ34687445
p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loopQ34794097
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JNK targets p53 ubiquitination and degradation in nonstressed cellsQ35208651
CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumorsQ35289071
Role of apoptosis in reperfusion injuryQ35666886
Chaperoning of mutant p53 protein by wild-type p53 protein causes hypoxic tumor regressionQ35710194
The mitochondrial death pathway and cardiac myocyte apoptosisQ35946473
The thioredoxin system in retroviral infection and apoptosisQ36092819
The P53 pathway: what questions remain to be explored?Q36430168
Some p53-binding proteins that can function as arbiters of life and death.Q36436693
Outcomes of p53 activation--spoilt for choiceQ36678791
The ARF/oncogene pathway activates p53 acetylation within the DNA binding domainQ36833807
Pharmacological preconditioning with hyperbaric oxygen: can this therapy attenuate myocardial ischemic reperfusion injury and induce myocardial protection via nitric oxide?Q36998523
The dark side of a tumor suppressor: anti-apoptotic p53.Q37115437
Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heartQ37245118
Tied up in loops: positive and negative autoregulation of p53.Q37746500
Oxygen therapy for acute myocardial infarction-then and now. A century of uncertaintyQ37948167
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Redox modulation of p53 conformation and sequence-specific DNA binding in vitro.Q38315428
Correlation between inducible nitric oxide synthase and p53 expression for DMBA-induced hamster buccal-pouch carcinomasQ38481492
Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53Q39790463
Oxygen cycling in conjunction with stem cell transplantation induces NOS3 expression leading to attenuation of fibrosis and improved cardiac functionQ39923212
Regulation of p53 by activated protein kinase C-delta during nitric oxide-induced dopaminergic cell deathQ40346478
p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis.Q40571016
Transcriptional activation of the human glutathione peroxidase promoter by p53.Q40960162
A novel p53-inducible gene coding for a microtubule-localized protein with G2-phase-specific expressionQ41011656
Acetylation of the p53 DNA-binding domain regulates apoptosis inductionQ43019120
Apoptosis induced by capsaicin and resveratrol in colon carcinoma cells requires nitric oxide production and caspase activation.Q43257200
Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosisQ45345472
Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in ratsQ47341587
Oxygen therapy in myocardial infarction: an historical perspectiveQ53202744
P433issue11
P304page(s)1662-1683
P577publication date2013-10-01
P1433published inEMBO Molecular MedicineQ15817279
P1476titlep53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation
P478volume5

Reverse relations

cites work (P2860)
Q41832646Co-expression of POU4F2/Brn-3b with p53 may be important for controlling expression of pro-apoptotic genes in cardiomyocytes following ischaemic/hypoxic insults
Q36170947Depletion of Tip60 from In Vivo Cardiomyocytes Increases Myocyte Density, Followed by Cardiac Dysfunction, Myocyte Fallout and Lethality
Q90401953Expression of miRNAs-122, -192 and -499 in end stage renal disease associated with acute myocardial infarction
Q90185014HIF-transcribed p53 chaperones HIF-1α
Q90346658NGS-identified circulating miR-375 as a potential regulating component of myocardial infarction associated network
Q36282692No Evidence of Myocardial Oxygen Deprivation in Nonischemic Heart Failure.
Q60927794The Crosstalk between Acetylation and Phosphorylation: Emerging New Roles for HDAC Inhibitors in the Heart
Q49571721The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53.
Q51415426Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.

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