scholarly article | Q13442814 |
P50 | author | Christopher Shaw | Q24005568 |
Caroline Vance | Q42649168 | ||
Eva So | Q85459143 | ||
George Chennell | Q88174775 | ||
P2093 | author name string | Gema Vizcay-Barrena | |
Jacqueline C Mitchell | |||
Caroline Memmi | |||
Leanne Allison | |||
P2860 | cites work | The Microprocessor complex mediates the genesis of microRNAs | Q24312976 |
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import | Q24630100 | ||
Neuromuscular Junctions as Key Contributors and Therapeutic Targets in Spinal Muscular Atrophy | Q26766502 | ||
Ultrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesis | Q26782995 | ||
Oxidative stress and mitochondrial damage: importance in non-SOD1 ALS | Q27023941 | ||
FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration | Q27342067 | ||
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis | Q28236796 | ||
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 | Q28236805 | ||
TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines | Q28284342 | ||
FUS Interacts with HSP60 to Promote Mitochondrial Damage | Q28547727 | ||
Delocalization of the multifunctional RNA splicing factor TLS/FUS in hippocampal neurones: exclusion from the nucleus and accumulation in dendritic granules and spine heads | Q28582163 | ||
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2. | Q30456334 | ||
Deficits in axonal transport precede ALS symptoms in vivo | Q30497554 | ||
Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion | Q30532680 | ||
Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models | Q30572264 | ||
Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice. | Q33700562 | ||
The ALS gene FUS regulates synaptic transmission at the Drosophila neuromuscular junction. | Q33784500 | ||
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. | Q34136342 | ||
Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions | Q34183099 | ||
FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations | Q34209561 | ||
Activity-dependent FUS dysregulation disrupts synaptic homeostasis | Q34480824 | ||
Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice | Q34664325 | ||
Early changes of neuromuscular transmission in the SOD1(G93A) mice model of ALS start long before motor symptoms onset | Q34989403 | ||
ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP. | Q35114564 | ||
Identification of a critical period for motor development in neonatal rats | Q35661953 | ||
Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS | Q35887683 | ||
Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats | Q36317708 | ||
Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons | Q36453024 | ||
ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function | Q36548825 | ||
Mitochondrial dynamics and bioenergetic dysfunction is associated with synaptic alterations in mutant SOD1 motor neurons | Q36593996 | ||
Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes | Q36709139 | ||
ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules | Q36908224 | ||
Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy | Q37294764 | ||
The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules | Q37379010 | ||
Defects in synapse structure and function precede motor neuron degeneration in Drosophila models of FUS-related ALS. | Q37381821 | ||
Mitochondrial dysfunction in amyotrophic lateral sclerosis. | Q37588819 | ||
Review: neuromuscular synaptic vulnerability in motor neurone disease: amyotrophic lateral sclerosis and spinal muscular atrophy | Q37702459 | ||
RNA processing pathways in amyotrophic lateral sclerosis | Q37720436 | ||
Mitochondrial dysfunction is a converging point of multiple pathological pathways in amyotrophic lateral sclerosis | Q37750234 | ||
The "dying-back" phenomenon of motor neurons in ALS. | Q37807909 | ||
Synaptic changes in Alzheimer's disease and its models | Q38017867 | ||
Mechanisms underlying synaptic vulnerability and degeneration in neurodegenerative disease | Q38071648 | ||
Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS. | Q38314794 | ||
Early synaptic dysfunction in Parkinson's disease: Insights from animal models. | Q38837604 | ||
Genetic epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis. | Q39069154 | ||
ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN. | Q39150934 | ||
Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations | Q39464446 | ||
FUS/TLS is a novel mediator of androgen-dependent cell-cycle progression and prostate cancer growth. | Q39618319 | ||
Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis | Q41842786 | ||
FUS regulates AMPA receptor function and FTLD/ALS-associated behaviour via GluA1 mRNA stabilization | Q41950782 | ||
ALS-FUS pathology revisited: singleton FUS mutations and an unusual case with both a FUS and TARDBP mutation | Q42003982 | ||
Neuromuscular junction protection for the potential treatment of amyotrophic lateral sclerosis | Q42285046 | ||
Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy | Q42732668 | ||
Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity. | Q43777123 | ||
Mitochondria, motor neurons and aging | Q44577873 | ||
Calcium channel agonists protect against neuromuscular dysfunction in a genetic model of TDP-43 mutation in ALS. | Q45929410 | ||
The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology. | Q46409672 | ||
Mutations in the 3' untranslated region of FUS causing FUS overexpression are associated with amyotrophic lateral sclerosis. | Q48021519 | ||
Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man | Q75310510 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 3 | |
P921 | main subject | neuromuscular junction | Q776995 |
P304 | page(s) | 463-474 | |
P577 | publication date | 2018-02-01 | |
P1433 | published in | Human Molecular Genetics | Q2720965 |
P1476 | title | Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUSWT transgenic mice | |
P478 | volume | 27 |
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