Understanding the regulation of APOBEC3 expression: Current evidence and much to learn.

scientific article published on 15 December 2017

Understanding the regulation of APOBEC3 expression: Current evidence and much to learn. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JLB.2MR0717-310R
P698PubMed publication ID29345375

P50authorLaura FantuzziQ56333769
Daniela Angela CovinoQ56810178
Maria Cristina GauzziQ56810183
P2860cites workLambda interferon inhibits human immunodeficiency virus type 1 infection of macrophagesQ24650069
Induction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti-HIV-1 activityQ24677778
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif proteinQ27860488
Surfing the p53 networkQ28032484
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpointsQ28266170
DNA replication stress mediates APOBEC3 family mutagenesis in breast cancerQ28830105
HIV-1 Gag-virus-like particles inhibit HIV-1 replication in dendritic cells and T cells through IFN-α-dependent upregulation of APOBEC3G and 3F.Q30418622
Differences in APOBEC3G expression in CD4+ T helper lymphocyte subtypes modulate HIV-1 infectivityQ33406252
Reassessing the role of APOBEC3G in human immunodeficiency virus type 1 infection of quiescent CD4+ T-cellsQ33419833
The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cellsQ33615181
17β-estradiol protects primary macrophages against HIV infection through induction of interferon-alphaQ33631612
CCR6 ligands inhibit HIV by inducing APOBEC3G.Q33697355
APOBEC3B, a molecular driver of mutagenesis in human cancersQ33743603
Human Beta Defensin 2 Selectively Inhibits HIV-1 in Highly Permissive CCR6⁺CD4⁺ T Cells.Q33753961
Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stressQ33997846
A common path to innate immunity to HIV-1 induced by Toll-like receptor ligands in primary human macrophagesQ34014512
Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restrictionQ34020228
APOBEC3A is a specific inhibitor of the early phases of HIV-1 infection in myeloid cells.Q34037651
Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoformsQ34107265
Interferon-alpha Induces High Expression of APOBEC3G and STAT-1 in Vitro and in VivoQ34205642
IFN-λ3 inhibits HIV infection of macrophages through the JAK-STAT pathwayQ34256897
Evidence for APOBEC3B mutagenesis in multiple human cancersQ34357412
Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancersQ34491947
NFAT and IRF Proteins Regulate Transcription of the Anti-HIV Gene, APOBEC3GQ34509329
Endogenous CCL2 neutralization restricts HIV-1 replication in primary human macrophages by inhibiting viral DNA accumulationQ35041156
Structural variants of IFNα preferentially promote antiviral functionsQ35197399
APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophagesQ35543248
Target cell-mediated editing of HIV-1 cDNA by APOBEC3 proteins in human macrophages.Q35599400
DNA damage tumor suppressor genes and genomic instabilityQ35755997
APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cellsQ45397134
IRF-4 expression in the human myeloid lineage: up-regulation during dendritic cell differentiation and inhibition by 1alpha,25-dihydroxyvitamin D3.Q46437047
The nerve growth factor reduces APOBEC3G synthesis and enhances HIV-1 transcription and replication in human primary macrophages.Q54621358
Myeloid differentiation and susceptibility to HIV-1 are linked to APOBEC3 expressionQ35850696
Apoptosis and genomic instabilityQ35876010
APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infectionQ36228190
The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancersQ36244879
Transcriptional regulation of APOBEC3 antiviral immunity through the CBF-β/RUNX axisQ36276957
Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G.Q36328929
The antiviral factor APOBEC3G enhances the recognition of HIV-infected primary T cells by natural killer cells.Q36490746
APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replicationQ36506737
RIG-I activation inhibits HIV replication in macrophagesQ37022843
Double-stranded RNA analog poly(I:C) inhibits human immunodeficiency virus amplification in dendritic cells via type I interferon-mediated activation of APOBEC3G.Q37033387
Functional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses.Q37073310
Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cellsQ37122075
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancersQ37211712
Defining APOBEC3 expression patterns in human tissues and hematopoietic cell subsetsQ37333883
Interleukin-27 inhibition of HIV-1 involves an intermediate induction of type I interferonQ37334618
IFN-ε protects primary macrophages against HIV infectionQ37469163
The interface between the innate interferon response and expression of host retroviral restriction factorsQ37772341
Innate immune evasion strategies by human immunodeficiency virus type 1.Q38139934
Advances in anti-viral immune defence: revealing the importance of the IFN JAK/STAT pathway.Q38692134
Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription FactorQ38721814
Classical NF-κB pathway is responsible for APOBEC3B expression in cancer cells.Q38748945
Modulating APOBEC expression enhances DNA vaccine immunogenicityQ38870396
Identification of APOBEC3B promoter elements responsible for activation by human papillomavirus type 16 E6.Q38896105
Interferon epsilon promotes HIV restriction at multiple steps of viral replicationQ39043504
Increased APOBEC3B Predicts Worse Outcomes in Lung Cancer: A Comprehensive Retrospective StudyQ39852184
Sp1 and Sp3 regulate basal transcription of the human APOBEC3G geneQ40129583
Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cellsQ40207497
Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replicationQ40275011
The Cytidine Deaminase APOBEC3 Family Is Subject to Transcriptional Regulation by p53.Q40319984
Plastic restriction of HIV-1 replication in human macrophages derived from M1/M2 polarized monocytes.Q40473707
Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumorsQ40513376
Transcriptional regulation of APOBEC3G, a cytidine deaminase that hypermutates human immunodeficiency virusQ40527917
Increased expression with differential subcellular location of cytidine deaminase APOBEC3G in human CD4(+) T-cell activation and dendritic cell maturation.Q40751332
High APOBEC3B expression is a predictor of recurrence in patients with low-risk clear cell renal cell carcinomaQ41688195
The role of cytidine deaminases on innate immune responses against human viral infections.Q41812539
Differential expression of HIV-1 interfering factors in monocyte-derived macrophages stimulated with polarizing cytokines or interferonsQ42010307
B-Myb Induces APOBEC3B Expression Leading to Somatic Mutation in Multiple CancersQ42253948
IFN-α induces APOBEC3G, F, and A in immature dendritic cells and limits HIV-1 spread to CD4+ T cells.Q42274165
APOBEC3B mutagenesis in cancerQ42396092
The interferon-induced expression of APOBEC3G in human blood-brain barrier exerts a potent intrinsic immunity to block HIV-1 entry to central nervous systemQ42545124
Alpha interferon potently enhances the anti-human immunodeficiency virus type 1 activity of APOBEC3G in resting primary CD4 T cellsQ42799017
M1 polarization of human monocyte-derived macrophages restricts pre and postintegration steps of HIV-1 replication.Q43837736
P433issue3
P304page(s)433-444
P577publication date2017-12-15
P1433published inJournal of Leukocyte BiologyQ1524048
P1476titleUnderstanding the regulation of APOBEC3 expression: Current evidence and much to learn
P478volume103

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