CRISPR-Cas Targeting of Host Genes as an Antiviral Strategy

scientific article published on 16 January 2018

CRISPR-Cas Targeting of Host Genes as an Antiviral Strategy is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3390/V10010040
P932PMC publication ID5795453
P698PubMed publication ID29337866

P2093author name stringXiao Yu
Shuliang Chen
Deyin Guo
P2860cites workGeminivirus disease complexes: the threat is spreading.Q51225581
C2c1-sgRNA Complex Structure Reveals RNA-Guided DNA Cleavage Mechanism.Q51252507
Generation of knockout mice by Cpf1-mediated gene targeting.Q51715364
HIV: Shock and kill.Q55056512
Guidelines for Confidentiality in Research on AIDSQ72416943
Genome-scale RNAi screen for host factors required for HIV replicationQ79769455
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virusQ21128797
Hepatitis B virus X protein upregulates HSP90alpha expression via activation of c-Myc in human hepatocarcinoma cell line, HepG2Q21245106
Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas SystemsQ21508512
HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled ReceptorQ22242268
Identification of a major co-receptor for primary isolates of HIV-1Q22251282
Newly identified host factors modulate HIV replicationQ22252434
HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiencyQ24300016
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria MarburgvirusQ24301153
LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cellsQ24304259
Identification of host proteins required for HIV infection through a functional genomic screenQ24306298
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMCQ24329089
Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infectionQ24329155
Ebola virus entry requires the cholesterol transporter Niemann-Pick C1Q24329246
Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infectionQ24336824
Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virusQ24337838
Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo studyQ40668686
Lentivirus pre-packed with Cas9 protein for safer gene editingQ40725476
CRISPR/Cas9 produces anti-hepatitis B virus effect in hepatoma cells and transgenic mouseQ40726923
Inhibition of hepatitis B virus by the CRISPR/Cas9 system via targeting the conserved regions of the viral genomeQ41026337
Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cellsQ41265657
SAMHD1: a new contributor to HIV-1 restriction in resting CD4+ T-cells.Q41384553
Harnessing the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated Cas9 system to disrupt the hepatitis B virusQ41503381
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detectionQ41558629
Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonucleaseQ41566723
Establishing a CRISPR-Cas-like immune system conferring DNA virus resistance in plants.Q41573592
CRISPR/Cas9-mediated genome editing of Epstein-Barr virus in human cells.Q41601689
Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm.Q41676229
Cells nonproductively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: a molecular model for latencyQ41730261
Phase 2 Placebo-Controlled Trial of Two Vaccines to Prevent Ebola in LiberiaQ41918936
Chaperone activation of the hepadnaviral reverse transcriptase for template RNA binding is established by the Hsp70 and stimulated by the Hsp90 systemQ41933522
Expanding CRISPR/Cas9 Genome Editing Capacity in Zebrafish Using SaCas9.Q42130461
Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.Q42152380
Study of accuracy of colposcopy in VIA and HPV detection-based cervical cancer screening programQ42177590
Establishment of three new genera in the family Geminiviridae: Becurtovirus, Eragrovirus and TurncurtovirusQ42229655
In vitro activity of cepharanthine hydrochloride against clinical wild-type and lamivudine-resistant hepatitis B virus isolatesQ42720808
Impact of human papillomavirus (HPV)-6/11/16/18 vaccine on all HPV-associated genital diseases in young womenQ43655015
Ebola virus disease: an update on post-exposure prophylaxisQ44106299
Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.Q45396940
Human immunodeficiency virus type 1 restriction by human-rhesus chimeric tripartite motif 5alpha (TRIM 5alpha) in CD34(+) cell-derived macrophages in vitro and in T cells in vivo in severe combined immunodeficient (SCID-hu) mice transplanted with huQ45397087
Gamma-adaptin, a novel ubiquitin-interacting adaptor, and Nedd4 ubiquitin ligase control hepatitis B virus maturationQ45414100
Genome modification of CXCR4 by Staphylococcus aureus Cas9 renders cells resistance to HIV-1 infectionQ45874506
Targeting TRIM5α in HIV Cure Strategies for the CRISPR-Cas9 Era.Q45875539
RNA targeting with CRISPR-Cas13.Q46092009
RNA editing with CRISPR-Cas13.Q47410076
Angiotensin-converting enzyme 2 protects from severe acute lung failureQ47768368
Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cellsQ48210394
Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infectionQ33854184
A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.Q33906477
Generation of marker-free transgenic plants concurrently resistant to a DNA geminivirus and a RNA tospovirusQ33912700
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection.Q34025414
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complexQ34042665
In vivo genome editing using Staphylococcus aureus Cas9Q34043628
Cas9-mediated targeting of viral RNA in eukaryotic cellsQ34043858
MX2 is an interferon-induced inhibitor of HIV-1 infectionQ24338311
SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by NefQ24338889
HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporationQ24338895
Hepatitis B virus large envelope protein interacts with gamma2-adaptin, a clathrin adaptor-related proteinQ24529521
A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletionQ24568052
RNA-guided human genome engineering via Cas9Q24598394
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by VpxQ24605940
Multiplex genome engineering using CRISPR/Cas systemsQ24609428
SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cellsQ24615124
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphatesQ24624362
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotesQ24625361
Ebola virus entry requires the host-programmed recognition of an intracellular receptorQ24629282
Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 proteinQ24635842
Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas systemQ24669821
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial ImmunityQ24669850
Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screensQ24705236
A CRISPR screen defines a signal peptide processing pathway required by flavivirusesQ24705237
Identification of Zika Virus and Dengue Virus Dependency Factors using Functional GenomicsQ24706780
Methods and clinical development of adenovirus-vectored vaccines against mucosal pathogensQ26750912
Application of CRISPR/Cas9 Technology to HBVQ26779150
CCR5 Targeted Cell Therapy for HIV and Prevention of Viral EscapeQ26801498
The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapyQ26849265
HIV-1 eradication strategies: design and assessmentQ26864933
Adenovirus vectors for gene therapy, vaccination and cancer gene therapyQ27001601
Epstein-barr virus sequence variation-biology and diseaseQ27003183
Novel mechanisms of EBV-induced oncogenesisQ27006524
CRISPR-Cas systems: Prokaryotes upgrade to adaptive immunityQ27014828
HIV-HCV co-infection: epidemiology, pathogenesis and therapeutic implicationsQ27026182
Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferaseQ27487986
CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 ReplicationQ27672646
Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4Q27678981
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNAQ27681727
CRISPR/Cas9-mediated viral interference in plantsQ34045362
Inactivation of the human papillomavirus E6 or E7 gene in cervical carcinoma cells by using a bacterial CRISPR/Cas RNA-guided endonuclease.Q34261483
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapyQ34290545
The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus.Q34318146
The spatio-temporal distribution dynamics of Ebola virus proteins and RNA in infected cellsQ34326340
A CRISPR/Cas system mediates bacterial innate immune evasion and virulenceQ34339102
Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B virusesQ34407460
The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In VivoQ34459390
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virusQ34478938
A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell DeathQ34485801
Inhibition of HSV-1 Replication by Gene Editing StrategyQ34521509
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.Q34522844
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effectorQ34529451
RNA-guided endonuclease provides a therapeutic strategy to cure latent herpesviridae infectionQ34583415
Towards an HIV cure: a global scientific strategyQ34640562
Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirusQ34655645
Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP).Q34693445
Removal of arginine 332 allows human TRIM5alpha to bind human immunodeficiency virus capsids and to restrict infectionQ34717834
Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9Q34727851
Targeting Hepatitis B Virus With CRISPR/Cas9.Q34745348
EBV-driven B-cell lymphoproliferative disorders: from biology, classification and differential diagnosis to clinical managementQ35040644
High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cellsQ35143589
A Dual-reporter system for real-time monitoring and high-throughput CRISPR/Cas9 library screening of the hepatitis C virusQ35157137
High-efficiency targeted editing of large viral genomes by RNA-guided nucleasesQ35161635
The CRISPR/Cas9 system inactivates latent HIV-1 proviral DNAQ35177829
Human papillomaviruses: targeting differentiating epithelial cells for malignant transformationQ35196630
Does Tyrosyl DNA Phosphodiesterase-2 Play a Role in Hepatitis B Virus Genome Repair?Q35664939
Identification of BST-2/tetherin-induced hepatitis B virus restriction and hepatocyte-specific BST-2 inactivationQ35792954
The Interferon-Inducible Protein Tetherin Inhibits Hepatitis B Virus Virion SecretionQ35973592
Dual gRNAs guided CRISPR/Cas9 system inhibits hepatitis B virus replicationQ35992385
Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNAQ35999041
Post-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle.Q36069580
The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2Q36152782
Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection.Q36181852
STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognitionQ27701410
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif proteinQ27860488
Replication of hepatitis C virusQ27860957
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNAQ27861124
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirusQ28188496
Characterization of a novel coronavirus associated with severe acute respiratory syndromeQ28202401
Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIVQ28235281
Development and applications of CRISPR-Cas9 for genome engineeringQ28241526
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injuryQ28260798
HIV entry and its inhibitionQ28273919
Update on acquired immune deficiency syndrome (AIDS)--United StatesQ28274386
Small CRISPR RNAs guide antiviral defense in prokaryotesQ28290898
RNA-guided gene activation by CRISPR-Cas9-based transcription factorsQ28295458
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNAQ28297640
Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantationQ28300338
CCR5 gene disruption via lentiviral vectors expressing Cas9 and single guided RNA renders cells resistant to HIV-1 infectionQ28542878
CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent InfectionsQ28552274
Nucleic acid detection with CRISPR-Cas13a/C2c2Q29385392
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study InvestigatorsQ29547281
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeysQ29547689
Tetherin inhibits retrovirus release and is antagonized by HIV-1 VpuQ29547836
Papillomaviruses and cancer: from basic studies to clinical applicationQ29614745
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantationQ29615068
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expressionQ29615784
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapyQ29615992
Genome-scale CRISPR-Cas9 knockout screening in human cellsQ29616044
Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replicationQ29616375
CRISPR RNA-guided activation of endogenous human genesQ29617072
Genetic screens in human cells using the CRISPR-Cas9 systemQ29617411
The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu proteinQ29619540
Diagnosis, management, and treatment of hepatitis CQ29620656
A CRISPR toolbox to study virus-host interactionsQ29994612
SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.Q30421200
A protein-tagging system for signal amplification in gene expression and fluorescence imagingQ30604320
Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletionQ33450556
Generation of human TRIM5alpha mutants with high HIV-1 restriction activityQ33548284
Characterization of human immunodeficiency virus type 1 populations containing CXCR4-using variants from recently infected individualsQ33685141
Efficient inhibition of hepatitis B virus infection by acylated peptides derived from the large viral surface proteinQ33717942
Heat stress cognate 70 host protein as a potential drug target against drug resistance in hepatitis B virusQ33826248
CRISPR/Cas9-The ultimate weapon to battle infectious diseases?Q36196813
The CXCL12/CXCR4 Signaling Pathway: A New Susceptibility Factor in Human Papillomavirus PathogenesisQ36213484
CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirsQ36250079
Crystal Structure of Staphylococcus aureus Cas9Q36348284
Molecular dissection of HBV evasion from restriction factor tetherin: A new perspective for antiviral cell therapyQ36355811
Change in coreceptor use correlates with disease progression in HIV-1--infected individualsQ36376800
Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activatorsQ36435381
CRISPR-mediated Activation of Latent HIV-1 ExpressionQ36675297
Specific Reactivation of Latent HIV-1 by dCas9-SunTag-VP64-mediated Guide RNA Targeting the HIV-1 PromoterQ36675349
Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor templateQ36684377
Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors.Q36828138
Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expressionQ36830303
Highly specific targeted mutagenesis in plants using Staphylococcus aureus Cas9Q36937761
The clinical applications of genome editing in HIV.Q36942032
Immune responses to AAV vectors: overcoming barriers to successful gene therapyQ36983740
A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif).Q37095343
Immunity to adeno-associated virus vectors in animals and humans: a continued challengeQ37127246
Efficient Production of Gene-Modified Mice using Staphylococcus aureus Cas9.Q37227736
Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human componentsQ37363070
The challenge of finding a cure for HIV infectionQ37407598
Brd4 Activates Early Viral Transcription upon Human Papillomavirus 18 Infection of Primary KeratinocytesQ37430517
A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T CellsQ37441674
Efficient targeted mutagenesis of rice and tobacco genomes using Cpf1 from Francisella novicidaQ37460202
Multiplex gene editing by CRISPR-Cpf1 using a single crRNA arrayQ37578175
Removal of Integrated Hepatitis B Virus DNA Using CRISPR-Cas9.Q37714431
Hsp90 is required for the activity of a hepatitis B virus reverse transcriptaseQ37729269
Human papillomavirus oncoproteins: pathways to transformationQ37769103
Oxidative stress and mitochondrial impairment after treatment with anti-HIV drugs: clinical implicationsQ37970464
Developing strategies for HIV-1 eradicationQ38032363
Geminiviruses: masters at redirecting and reprogramming plant processesQ38150077
Dynamic Epstein-Barr virus gene expression on the path to B-cell transformationQ38174306
The immunology of Epstein-Barr virus-induced diseaseQ38364278
Delivery and Specificity of CRISPR-Cas9 Genome Editing Technologies for Human Gene Therapy.Q38525774
Highly efficient homology-driven genome editing in human T cells by combining zinc-finger nuclease mRNA and AAV6 donor delivery.Q38530599
CRISPR/Cas9-based tools for targeted genome editing and replication control of HBV.Q38618922
Complete Spectrum of CRISPR/Cas9-induced Mutations on HBV cccDNA.Q38769680
Two Distant Catalytic Sites Are Responsible for C2c2 RNase ActivitiesQ38770695
Potent and Targeted Activation of Latent HIV-1 Using the CRISPR/dCas9 Activator ComplexQ38818673
Inhibition of HIV-1 infection of primary CD4+ T-cells by gene editing of CCR5 using adenovirus-delivered CRISPR/Cas9.Q38889625
Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication.Q38890817
A CRISPR-Cpf1 system for efficient genome editing and transcriptional repression in plants.Q38955410
In vitro and in vivo growth suppression of human papillomavirus 16-positive cervical cancer cells by CRISPR/Cas9.Q38973597
TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanismQ38983286
Host cell restriction factors that limit transcription and replication of human papillomavirus.Q39013547
Cyclosporin A inhibits hepatitis B and hepatitis D virus entry by cyclophilin-independent interference with the NTCP receptorQ39051196
Generation of an HIV resistant T-cell line by targeted "stacking" of restriction factorsQ39203103
CRISPR/Cas9: at the cutting edge of hepatology.Q39294371
A decade of discovery: CRISPR functions and applicationsQ39350951
Cpf1 Is A Versatile Tool for CRISPR Genome Editing Across Diverse Species of CyanobacteriaQ39613576
Simultaneous Knockout of CXCR4 and CCR5 Genes in CD4+ T Cells via CRISPR/Cas9 Confers Resistance to Both X4- and R5-Tropic Human Immunodeficiency Virus Type 1 InfectionQ39619539
Heat shock protein 90 facilitates formation of the HBV capsid via interacting with the HBV core protein dimers.Q39624638
Genome editing of the HIV co-receptors CCR5 and CXCR4 by CRISPR-Cas9 protects CD4+ T cells from HIV-1 infectionQ40042102
The gRNA-miRNA-gRNA Ternary Cassette Combining CRISPR/Cas9 with RNAi Approach Strongly Inhibits Hepatitis B Virus ReplicationQ40070996
A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host FactorQ40081243
The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases.Q40101206
CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In VivoQ40192805
CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency FactorsQ40205659
In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal ModelsQ40263108
Hepatitis B Virus-Infected HepG2hNTCP Cells Serve as a Novel Immunological Tool To Analyze the Antiviral Efficacy of CD8+ T Cells In VitroQ40280446
The Deacetylase SIRT1 Regulates the Replication Properties of Human Papillomavirus 16 E1 and E2.Q40301195
A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo.Q40360360
PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas EndonucleaseQ40406605
Down-regulation of microRNA-146a is associated with high-risk human papillomavirus infection and epidermal growth factor receptor overexpression in penile squamous cell carcinoma.Q40462022
KLF13 regulates the differentiation-dependent human papillomavirus life cycle in keratinocytes through STAT5 and IL-8.Q40500885
CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X.Q40580426
CRISPR/Cas9-Mediated Immunity to Geminiviruses: Differential Interference and Evasion.Q40659541
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectregulation of gene expressionQ411391
CRISPRQ412563
viral infectious diseaseQ1928978
gene editingQ65363531
biomedical investigative techniqueQ66648976
host microbial interactionQ68260314
CRISPR-Cas systemsQ71149179
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)40
P577publication date2018-01-16
P1433published inVirusesQ7935305
P1476titleCRISPR-Cas Targeting of Host Genes as an Antiviral Strategy
P478volume10

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cites work (P2860)
Q64060697Application of CRISPR/Cas9-Based Gene Editing in HIV-1/AIDS Therapy
Q91970445Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
Q64923390CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4+ T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4+ T cell enrichment in humanized mice.
Q55333943Cell Line Techniques and Gene Editing Tools for Antibody Production: A Review.
Q52431359Genome scale screening identification of SaCas9/gRNAs for targeting HIV-1 provirus and suppression of HIV-1 infection.
Q55190209HIV-1 inhibition in cells with CXCR4 mutant genome created by CRISPR-Cas9 and piggyBac recombinant technologies.
Q90061988Special Issue: Applications of CRISPR Technology in Virology 2018
Q92814609The Revival of the Battle between David and Goliath in the Enteric Viruses and Microbiota Struggle: Potential Implication for Celiac Disease

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