| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0969-9961(03)00087-1 |
| P698 | PubMed publication ID | 13678668 |
| P2093 | author name string | Robert A Floyd | |
| Kenneth Hensley | |||
| Paula Grammas | |||
| Melinda West | |||
| Charles Stewart | |||
| Brian Gordon | |||
| Kelly S Williamson | |||
| Quentin N Pye | |||
| Ladan Hamdheydari | |||
| Shenyun Mou | |||
| Joe Fedynyshyn | |||
| Molina Mhatre | |||
| Scott Ferrell | |||
| Stuart West | |||
| P433 | issue | 1 | |
| P921 | main subject | amyotrophic lateral sclerosis | Q206901 |
| TNF | Q18032037 | ||
| P304 | page(s) | 74-80 | |
| P577 | publication date | 2003-10-01 | |
| P1433 | published in | Neurobiology of Disease | Q15716606 |
| P1476 | title | Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis | |
| P478 | volume | 14 |
| Q36125335 | A comparative review of cell culture systems for the study of microglial biology in Alzheimer's disease |
| Q34029114 | A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function |
| Q28080614 | A perspective on stem cell modeling of amyotrophic lateral sclerosis |
| Q79323190 | Absence of tumor necrosis factor-alpha does not affect motor neuron disease caused by superoxide dismutase 1 mutations |
| Q33354106 | Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice |
| Q46893498 | Adult glial precursor proliferation in mutant SOD1G93A mice |
| Q35562672 | Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity |
| Q42730558 | Amyotrophic Lateral Sclerosis, a Multisystem Pathology: Insights into the Role of TNFα. |
| Q46798019 | Amyotrophic lateral sclerosis. Current clinical trials and underlying pathomechanisms |
| Q35964723 | Amyotrophic lateral sclerosis: contemporary concepts in etiopathogenesis and pharmacotherapy |
| Q38918965 | An anthocyanin-enriched extract from strawberries delays disease onset and extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis |
| Q36909735 | Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. |
| Q33535799 | Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS. |
| Q59544323 | Chapter 4 Molecular mechanisms of motor neuron degeneration in amyotrophic lateral sclerosis |
| Q27303112 | Chronic administration of AMD3100 increases survival and alleviates pathology in SOD1(G93A) mice model of ALS |
| Q50703301 | Chronic over-expression of TGFβ1 alters hippocampal structure and causes learning deficits. |
| Q38663343 | Comparison of the Neuroprotective and Anti-Inflammatory Effects of the Anthocyanin Metabolites, Protocatechuic Acid and 4-Hydroxybenzoic Acid. |
| Q48961308 | DJ-1 changes in G93A-SOD1 transgenic mice: implications for oxidative stress in ALS. |
| Q35623419 | Death Receptors in the Selective Degeneration of Motoneurons in Amyotrophic Lateral Sclerosis |
| Q36373508 | Deletion of galectin-3 exacerbates microglial activation and accelerates disease progression and demise in a SOD1(G93A) mouse model of amyotrophic lateral sclerosis |
| Q35626206 | Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model |
| Q38322767 | Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases |
| Q33975101 | Differential gene expression in the axotomized facial motor nucleus of presymptomatic SOD1 mice |
| Q38262690 | Disease origin and progression in amyotrophic lateral sclerosis: an immunology perspective. |
| Q38765043 | Disruption of the astrocytic TNFR1-GDNF axis accelerates motor neuron degeneration and disease progression in amyotrophic lateral sclerosis. |
| Q45796087 | Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis. |
| Q35064952 | Early-stage treatment with Withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral sclerosis |
| Q37440127 | Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and presymptomatic mSOD1 mice. |
| Q37288200 | Efficacy of thalidomide for the treatment of amyotrophic lateral sclerosis: a phase II open label clinical trial |
| Q33689422 | Evaluating the levels of interleukin-1 family cytokines in sporadic amyotrophic lateral sclerosis. |
| Q41832311 | Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene |
| Q36511926 | Gender differences in neurological disease: role of estrogens and cytokines |
| Q36251872 | Gene expression profiling in peripheral blood mononuclear cells from patients with sporadic amyotrophic lateral sclerosis (sALS) |
| Q51064372 | Genetic validation of a therapeutic target in a mouse model of ALS. |
| Q37902077 | Glial cells in amyotrophic lateral sclerosis |
| Q38214532 | Glial cells in amyotrophic lateral sclerosis |
| Q35092672 | IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1. |
| Q38123758 | Immune-mediated mechanisms in the pathoprogression of amyotrophic lateral sclerosis |
| Q47613084 | Impact of peripheral immune status on central molecular responses to facial nerve axotomy |
| Q36565671 | Implications for the kynurenine pathway and quinolinic acid in amyotrophic lateral sclerosis. |
| Q45298602 | Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease |
| Q46382135 | Inhibition of the transforming growth factor-β/SMAD cascade mitigates the anti-neurogenic effects of the carbamate pesticide carbofuran |
| Q63976942 | Inhibition of tumour necrosis factor alpha in the R6/2 mouse model of Huntington’s disease by etanercept treatment |
| Q36565649 | Inter- and intracellular signaling in amyotrophic lateral sclerosis: role of p38 mitogen-activated protein kinase |
| Q35986943 | Interleukin-6 Deficiency Does Not Affect Motor Neuron Disease Caused by Superoxide Dismutase 1 Mutation |
| Q36934383 | Intraperitoneally administered IgG from patients with amyotrophic lateral sclerosis or from an immune-mediated goat model increase the levels of TNF-α, IL-6, and IL-10 in the spinal cord and serum of mice. |
| Q33500473 | Lenalidomide (Revlimid) administration at symptom onset is neuroprotective in a mouse model of amyotrophic lateral sclerosis |
| Q35123965 | Melittin restores proteasome function in an animal model of ALS |
| Q36104618 | Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis |
| Q37592030 | Microglia in ALS: the good, the bad, and the resting |
| Q35027903 | Motor neuron trophic factors: Therapeutic use in ALS? |
| Q36437332 | Motor neuron-immune interactions: the vicious circle of ALS. |
| Q80673128 | Mutant Cu/Zn-superoxide dismutase associated with amyotrophic lateral sclerosis destabilizes vascular endothelial growth factor mRNA and downregulates its expression |
| Q34922649 | Neuregulin upregulates microglial α7 nicotinic acetylcholine receptor expression in immortalized cell lines: implications for regulating neuroinflammation |
| Q37220361 | Neuroinflammation in Alzheimer's disease: mechanisms, pathologic consequences, and potential for therapeutic manipulation |
| Q26776339 | Neuroinflammation in motor neuron disease |
| Q24623266 | Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis |
| Q43482550 | Neuroprotective effects of estradiol on motoneurons in a model of rat spinal cord embryonic explants |
| Q50232848 | Optineurin suppression causes neuronal cell death via NF-κB pathway. |
| Q91555508 | Peripheral proinflammatory Th1/Th17 immune cell shift is linked to disease severity in amyotrophic lateral sclerosis |
| Q54456955 | Pleiotropic functions of TNF-alpha determine distinct IKKbeta-dependent hepatocellular fates in response to LPS. |
| Q50765060 | Premature death of TDP-43 (A315T) transgenic mice due to gastrointestinal complications prior to development of full neurological symptoms of amyotrophic lateral sclerosis. |
| Q25256714 | Primary glia expressing the G93A-SOD1 mutation present a neuroinflammatory phenotype and provide a cellular system for studies of glial inflammation |
| Q34640800 | Progress in therapy development for amyotrophic lateral sclerosis |
| Q21245232 | Progressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosis |
| Q33720580 | Proteomic identification of binding partners for the brain metabolite lanthionine ketimine (LK) and documentation of LK effects on microglia and motoneuron cell cultures |
| Q58125223 | RANTES levels are elevated in serum and cerebrospinal fluid in patients with amyotrophic lateral sclerosis |
| Q33742737 | Redox modifier genes and pathways in amyotrophic lateral sclerosis |
| Q30446460 | Redox proteomics in selected neurodegenerative disorders: from its infancy to future applications. |
| Q40726584 | Reduced levels of alpha-1-antitrypsin in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a novel approach for a potential treatment |
| Q36835575 | Role of zinc in ALS. |
| Q37894600 | SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments |
| Q38184230 | SQSTM1 mutations--bridging Paget disease of bone and ALS/FTLD. |
| Q45741772 | Spinal astrocytes stimulated by tumor necrosis factor-α and/or interferon-γ attenuate connexin 43-gap junction via c-jun terminal kinase activity |
| Q33838658 | Spinal but not cortical microglia acquire an atypical phenotype with high VEGF, galectin-3 and osteopontin, and blunted inflammatory responses in ALS rats |
| Q33919781 | Stem cell-derived motor neurons: applications and challenges in amyotrophic lateral sclerosis |
| Q36707203 | Systemic infections and inflammation affect chronic neurodegeneration |
| Q36981080 | Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis. |
| Q36968498 | T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS. |
| Q36330960 | Targeting TNF-α to elucidate and ameliorate neuroinflammation in neurodegenerative diseases |
| Q81791749 | Temporal profiles of neuronal degeneration, glial proliferation, and cell death in hNFL(+/+) and NFL(-/-) mice |
| Q35121026 | Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation |
| Q38390908 | Thalidomide causes sinus bradycardia in ALS. |
| Q90207854 | The Role of Sex and Sex Hormones in Neurodegenerative Diseases |
| Q40513595 | The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice |
| Q42165757 | Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice |
| Q35777281 | Transforming Growth Factor Beta (TGF-β) Is a Muscle Biomarker of Disease Progression in ALS and Correlates with Smad Expression |
| Q30464085 | Translational research involving oxidative stress and diseases of aging |
| Q42468205 | Tumor necrosis factor reduces cAMP production in rat microglia |
| Q58170329 | Two consecutive pregnancies in early and late stage of amyotrophic lateral sclerosis |
| Q36332951 | Type I Vs. Type II Cytokine Levels as a Function of SOD1 G93A Mouse Amyotrophic Lateral Sclerosis Disease Progression |
| Q45030474 | Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity. |
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