Noxa/HSP27 complex delays degradation of ubiquitylated IkBα in airway epithelial cells to reduce pulmonary inflammation.

scientific article published on 24 January 2018

Noxa/HSP27 complex delays degradation of ubiquitylated IkBα in airway epithelial cells to reduce pulmonary inflammation. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MI.2017.117
P932PMC publication ID5976511
P698PubMed publication ID29363670

P50authorHitendra ChandQ38642014
Yohannes TesfaigziQ58492448
P2093author name stringC Zhang
J T Jones
M G Wathelet
J Xiang
B Dickey
C M Evans
Y A Mebratu
P2860cites workBH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alphaQ24303563
Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis.Q24529124
The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cellsQ24650702
HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradationQ24679412
The recognition of ubiquitinated proteins by the proteasomeQ26748001
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosisQ28144256
NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinaseQ28144326
Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B activationQ28182501
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxaQ28204059
Identification and characterization of hic-5/ARA55 as an hsp27 binding proteinQ28215667
Size matters: of the small HSP27 and its large oligomersQ28215719
The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cellsQ28246738
Deacetylation of p53 induces autophagy by suppressing Bmf expressionQ28510522
Dual role of proapoptotic BAD in insulin secretion and beta cell survivalQ28586275
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Nuclear factor-kappaB in cancer development and progressionQ29547879
BH3-only protein Bmf mediates apoptosis upon inhibition of CAP-dependent protein synthesisQ34191999
Heat shock protein B1-deficient mice display impaired wound healingQ35021738
The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cellsQ35121301
Anti-inflammatory properties of pro-inflammatory interferon-gammaQ35188637
Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infectionQ35441389
Suppression of heat shock protein 27 induces long-term dormancy in human breast cancerQ36001339
Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.Q36852678
The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNgamma-induced cell death.Q36955702
How interferon-gamma keeps autoimmune diseases in check.Q37262514
Apoptosis versus cell differentiation: role of heat shock proteins HSP90, HSP70 and HSP27Q37375811
Heat shock protein-27 protects human bronchial epithelial cells against oxidative stress-mediated apoptosis: possible implication in asthma.Q37490459
Noxa: at the tip of the balance between life and death.Q37566236
The biology of innate lymphoid cellsQ38319907
Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E.Q39747931
Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruptionQ40443440
Immortalization and transformation of primary human airway epithelial cells by gene transfer.Q40722115
Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activationQ41120985
Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation.Q41846014
Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells.Q42065869
Conditional expression of genes in the respiratory epithelium in transgenic mice: cautionary notes and toward building a better mouse trapQ43080106
IFNγ induces monopoiesis and inhibits neutrophil development during inflammationQ44581464
Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain.Q45086646
Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysemaQ46535470
Non-apoptotic role of BID in inflammation and innate immunity.Q50521157
Bax is crucial for IFN-gamma-induced resolution of allergen-induced mucus cell metaplasia.Q51698120
IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis.Q51719633
Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population.Q52547922
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responsesQ62819762
Dichotomic effects of IFN-gamma on the development of systemic lupus erythematosus-like syndrome in MRL-lpr / lpr miceQ64388661
IFN-gamma inhibits inflammatory cell recruitment and the evolution of bacterial cell wall-induced arthritisQ67982154
Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clonesQ70054755
Mucosal IFN-gamma gene transfer inhibits pulmonary allergic responses in miceQ71687712
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamiliesQ79370601
Analysis of eosinophil turnover in vivo reveals their active recruitment to and prolonged survival in the peritoneal cavityQ81317290
Heat shock protein 27 and cyclophilin A associate with the pathogenesis of COPDQ84129530
P433issue3
P921main subjectubiquitinationQ33059483
P304page(s)741-751
P577publication date2018-01-24
P1433published inMucosal ImmunologyQ15817743
P1476titleNoxa/HSP27 complex delays degradation of ubiquitylated IkBα in airway epithelial cells to reduce pulmonary inflammation
P478volume11

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